4JGFA

Crystal structure of the cataract-causing p23t gamma d-crystallin mutant
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
171
structure length
171
Chain Sequence
GKITLYEDRGFQGRHYECSSDHTNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRRGDYADHQQWMGLSDSVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNEIHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVID
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Structural protein
source organism Homo sapiens
publication title Crystal structure of the cataract-causing P23T gamma D-crystallin mutant.
pubmed doi rcsb
molecule keywords Gamma-crystallin D
total genus 43
structure length 171
sequence length 171
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-03-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00030 Crystall Beta/Gamma crystallin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.20.10 Mainly Beta Sandwich Gamma-B Crystallin; domain 1 Crystallins 4jgfA02
2.60.20.10 Mainly Beta Sandwich Gamma-B Crystallin; domain 1 Crystallins 4jgfA01
1AMMA 1OKIA 2JDFA 3LWKA 1BD7A 1AG4A 2B1OA 2BV2A 2M3CA 4FD9A 2K1XA 3QK3A 1I5IA 1GAMA 3HZ2A 4IAUA 1YHPA 3HZBA 1A45A 2NBRA 1NPSA 1ZWOA 1PRRA 1ZWMA 1ZGTA 1PRSA 2KFBA 3SO0A 5HT9A 3SNZA 1YTQA 2A5MA 1DSLA 2KP5A 1GCSA 2K1WA 2DADA 4W9BA 4EL6A 4JGFA 1ELPA 1ZIRA 1A7HA 1M8UA 2M3TA 3ENUA 3ENTA 4NI3A 3SNYA 3SO1A 1H4AX 1A5DA 1ZIEA 4AKAA 2G98A 3I9HA 4GCRA 1HA4A 3CW3A 2M3UA 1HDFA 4PSRA 4PSPA 5HT8A 4W9AA 2BB2A 1HK0X 2V2UA 3IAJA 4GR7A 1BLBA 1ZIQA 1E7NA 2JDGA
chains in the Genus database with same CATH superfamily
1AMMA 3QK3A 1GH5A 2NBRA 3SO0A 2K1WA 3UJZA 1ZIRA 1A7HA 1M8UA 2M3TA 3ENUA 3SO1A 1A5DA 1ZIEA 3I9HA 3CW3A 4PSRA 2V2UA 1E7NA 2JDGA 2JDFA 1BD7A 2B1OA 2M3CA 4FD9A 2K1XA 4IAUA 1NPSA 1ZWMA 1PRSA 3SNZA 1WKTA 2A5MA 2KP5A 1GCSA 4JGFA 3ENTA 4NI3A 2G98A 1BHUA 2M3UA 5HT8A 2BB2A 3IAJA 1OKIA 1AG4A 2BV2A 1I5IA 1YHPA 3HZBA 1BLBA 1ZWOA 2KFBA 1DSLA 3SNYA 4AKAA 1H4AX 4GCRA 1HDFA 4PSPA 4W9AA 3HZ2A 3LWKA 1GAMA 1A45A 1PRRA 1ZGTA 1G6EA 5HT9A 1YTQA 1F53A 4EL6A 2DADA 1C01A 1ELPA 1HA4A 4GR7A 1HK0X 4W9BA 1ZIQA
chains in the Genus database with same CATH topology
1AMMA 1OKIA 2JDFA 3LWKA 1BD7A 1AG4A 2B1OA 2BV2A 2M3CA 4FD9A 2K1XA 3QK3A 1I5IA 1GAMA 3HZ2A 4IAUA 1YHPA 3HZBA 1A45A 2NBRA 1NPSA 1ZWOA 1PRRA 1ZWMA 1ZGTA 1PRSA 2KFBA 3SO0A 5HT9A 3SNZA 1YTQA 2A5MA 1DSLA 2KP5A 1GCSA 2K1WA 2DADA 4W9BA 4EL6A 4JGFA 1ELPA 1ZIRA 1A7HA 1M8UA 2M3TA 3ENUA 3ENTA 4NI3A 3SNYA 3SO1A 1H4AX 1A5DA 1ZIEA 4AKAA 2G98A 3I9HA 4GCRA 1HA4A 3CW3A 2M3UA 1HDFA 4PSRA 4PSPA 5HT8A 4W9AA 2BB2A 1HK0X 2V2UA 3IAJA 4GR7A 1BLBA 1ZIQA 1E7NA 2JDGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AMM A;  1OKI A;  2JDF A;  3LWK A;  1BD7 A;  1AG4 A;  2B1O A;  2BV2 A;  2M3C A;  4FD9 A;  2K1X A;  3QK3 A;  1I5I A;  1GAM A;  3HZ2 A;  4IAU A;  1YHP A;  3HZB A;  1A45 A;  2NBR A;  1NPS A;  1ZWO A;  1PRR A;  1ZWM A;  1ZGT A;  1PRS A;  2KFB A;  3SO0 A;  5HT9 A;  3SNZ A;  1YTQ A;  2A5M A;  1DSL A;  2KP5 A;  1GCS A;  2K1W A;  2DAD A;  4W9B A;  4EL6 A;  4JGF A;  1ELP A;  1ZIR A;  1A7H A;  1M8U A;  2M3T A;  3ENU A;  3ENT A;  4NI3 A;  3SNY A;  3SO1 A;  1H4A X;  1A5D A;  1ZIE A;  4AKA A;  2G98 A;  3I9H A;  4GCR A;  1HA4 A;  3CW3 A;  2M3U A;  1HDF A;  4PSR A;  4PSP A;  5HT8 A;  4W9A A;  2BB2 A;  1HK0 X;  2V2U A;  3IAJ A;  4GR7 A;  1BLB A;  1ZIQ A;  1E7N A;  2JDG A; 
#chains in the Genus database with same CATH topology
 1AMM A;  3QK3 A;  1GH5 A;  2NBR A;  3SO0 A;  2K1W A;  3UJZ A;  1ZIR A;  1A7H A;  1M8U A;  2M3T A;  3ENU A;  3SO1 A;  1A5D A;  1ZIE A;  3I9H A;  3CW3 A;  4PSR A;  2V2U A;  1E7N A;  2JDG A;  2JDF A;  1BD7 A;  2B1O A;  2M3C A;  4FD9 A;  2K1X A;  4IAU A;  1NPS A;  1ZWM A;  1PRS A;  3SNZ A;  1WKT A;  2A5M A;  2KP5 A;  1GCS A;  4JGF A;  3ENT A;  4NI3 A;  2G98 A;  1BHU A;  2M3U A;  5HT8 A;  2BB2 A;  3IAJ A;  1OKI A;  1AG4 A;  2BV2 A;  1I5I A;  1YHP A;  3HZB A;  1BLB A;  1ZWO A;  2KFB A;  1DSL A;  3SNY A;  4AKA A;  1H4A X;  4GCR A;  1HDF A;  4PSP A;  4W9A A;  3HZ2 A;  3LWK A;  1GAM A;  1A45 A;  1PRR A;  1ZGT A;  1G6E A;  5HT9 A;  1YTQ A;  1F53 A;  4EL6 A;  2DAD A;  1C01 A;  1ELP A;  1HA4 A;  4GR7 A;  1HK0 X;  4W9B A;  1ZIQ A; 
#chains in the Genus database with same CATH homology
 1AMM A;  1OKI A;  2JDF A;  3LWK A;  1BD7 A;  1AG4 A;  2B1O A;  2BV2 A;  2M3C A;  4FD9 A;  2K1X A;  3QK3 A;  1I5I A;  1GAM A;  3HZ2 A;  4IAU A;  1YHP A;  3HZB A;  1A45 A;  2NBR A;  1NPS A;  1ZWO A;  1PRR A;  1ZWM A;  1ZGT A;  1PRS A;  2KFB A;  3SO0 A;  5HT9 A;  3SNZ A;  1YTQ A;  2A5M A;  1DSL A;  2KP5 A;  1GCS A;  2K1W A;  2DAD A;  4W9B A;  4EL6 A;  4JGF A;  1ELP A;  1ZIR A;  1A7H A;  1M8U A;  2M3T A;  3ENU A;  3ENT A;  4NI3 A;  3SNY A;  3SO1 A;  1H4A X;  1A5D A;  1ZIE A;  4AKA A;  2G98 A;  3I9H A;  4GCR A;  1HA4 A;  3CW3 A;  2M3U A;  1HDF A;  4PSR A;  4PSP A;  5HT8 A;  4W9A A;  2BB2 A;  1HK0 X;  2V2U A;  3IAJ A;  4GR7 A;  1BLB A;  1ZIQ A;  1E7N A;  2JDG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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