4JGF | Genus

Total Genus 43

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	43
sequence length	171
structure length	171
Chain Sequence	GKITLYEDRGFQGRHYECSSDHTNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRRGDYADHQQWMGLSDSVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNEIHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVID

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Structural protein
source organism	Homo sapiens
publication title	Crystal structure of the cataract-causing P23T gamma D-crystallin mutant. pubmed doi rcsb
molecule keywords	Gamma-crystallin D
total genus	43
structure length	171
sequence length	171
chains with identical sequence	B
ec nomenclature
pdb deposition date	2013-03-01

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00030	Crystall	Beta/Gamma crystallin

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.60.20.10	Mainly Beta	Sandwich	Gamma-B Crystallin; domain 1	Crystallins	4jgfA02
2.60.20.10	Mainly Beta	Sandwich	Gamma-B Crystallin; domain 1	Crystallins	4jgfA01

4EL6A 1ELPA 4GR7A 1OKIA 1AG4A 1A7HA 1GCSA 3QK3A 1ZIQA 1HA4A 4W9AA 3ENUA 2JDFA 2M3CA 4GCRA 4IAUA 3SNYA 1GAMA 1ZIRA 1ZGTA 2B1OA 1AMMA 3SNZA 1NPSA 3HZBA 1A5DA 3SO0A 5HT9A 1ZWOA 2KP5A 3LWKA 4JGFA 2DADA 4AKAA 1ZIEA 2M3TA 3SO1A 1E7NA 2A5MA 2G98A 1HK0X 1DSLA 2BV2A 2K1WA 2KFBA 2NBRA 5HT8A 1BD7A 1I5IA 1BLBA 1M8UA 1A45A 4W9BA 1ZWMA 2K1XA 1HDFA 2M3UA 4PSPA 2V2UA 4FD9A 4NI3A 1PRSA 2JDGA 3ENTA 1PRRA 3I9HA 3CW3A 3IAJA 2BB2A 1H4AX 1YTQA 4PSRA 1YHPA 3HZ2A
chains in the Genus database with same CATH superfamily

4GR7A 1AG4A 1GAMA 1ZGTA 4JGFA 2A5MA 1HK0X 1DSLA 2K1WA 2KFBA 1BD7A 1BLBA 4W9BA 1HDFA 3I9HA 1H4AX 4EL6A 1OKIA 3QK3A 1ZIQA 1HA4A 4W9AA 3ENUA 2M3CA 4IAUA 3SNYA 1A5DA 3UJZA 2KP5A 1BHUA 3LWKA 2DADA 2M3TA 1E7NA 1G6EA 1I5IA 1A45A 1F53A 2M3UA 1PRRA 1YTQA 1YHPA 1GCSA 1ZIRA 5HT9A 3SO0A 1ZWOA 4AKAA 1ZIEA 2G98A 1M8UA 1ZWMA 4PSPA 1PRSA 2JDGA 3ENTA 3CW3A 1C01A 2BB2A 2JDFA 1GH5A 1ELPA 1A7HA 4GCRA 2B1OA 1AMMA 3SNZA 1NPSA 3HZBA 3SO1A 2BV2A 2NBRA 5HT8A 1WKTA 2K1XA 4FD9A 4NI3A 3IAJA 4PSRA 2V2UA 3HZ2A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4EL6 A;  1ELP A;  4GR7 A;  1OKI A;  1AG4 A;  1A7H A;  1GCS A;  3QK3 A;  1ZIQ A;  1HA4 A;  4W9A A;  3ENU A;  2JDF A;  2M3C A;  4GCR A;  4IAU A;  3SNY A;  1GAM A;  1ZIR A;  1ZGT A;  2B1O A;  1AMM A;  3SNZ A;  1NPS A;  3HZB A;  1A5D A;  3SO0 A;  5HT9 A;  1ZWO A;  2KP5 A;  3LWK A;  4JGF A;  2DAD A;  4AKA A;  1ZIE A;  2M3T A;  3SO1 A;  1E7N A;  2A5M A;  2G98 A;  1HK0 X;  1DSL A;  2BV2 A;  2K1W A;  2KFB A;  2NBR A;  5HT8 A;  1BD7 A;  1I5I A;  1BLB A;  1M8U A;  1A45 A;  4W9B A;  1ZWM A;  2K1X A;  1HDF A;  2M3U A;  4PSP A;  2V2U A;  4FD9 A;  4NI3 A;  1PRS A;  2JDG A;  3ENT A;  1PRR A;  3I9H A;  3CW3 A;  3IAJ A;  2BB2 A;  1H4A X;  1YTQ A;  4PSR A;  1YHP A;  3HZ2 A; 
#chains in the Genus database with same CATH topology
 4GR7 A;  1AG4 A;  1GAM A;  1ZGT A;  4JGF A;  2A5M A;  1HK0 X;  1DSL A;  2K1W A;  2KFB A;  1BD7 A;  1BLB A;  4W9B A;  1HDF A;  3I9H A;  1H4A X;  4EL6 A;  1OKI A;  3QK3 A;  1ZIQ A;  1HA4 A;  4W9A A;  3ENU A;  2M3C A;  4IAU A;  3SNY A;  1A5D A;  3UJZ A;  2KP5 A;  1BHU A;  3LWK A;  2DAD A;  2M3T A;  1E7N A;  1G6E A;  1I5I A;  1A45 A;  1F53 A;  2M3U A;  1PRR A;  1YTQ A;  1YHP A;  1GCS A;  1ZIR A;  5HT9 A;  3SO0 A;  1ZWO A;  4AKA A;  1ZIE A;  2G98 A;  1M8U A;  1ZWM A;  4PSP A;  1PRS A;  2JDG A;  3ENT A;  3CW3 A;  1C01 A;  2BB2 A;  2JDF A;  1GH5 A;  1ELP A;  1A7H A;  4GCR A;  2B1O A;  1AMM A;  3SNZ A;  1NPS A;  3HZB A;  3SO1 A;  2BV2 A;  2NBR A;  5HT8 A;  1WKT A;  2K1X A;  4FD9 A;  4NI3 A;  3IAJ A;  4PSR A;  2V2U A;  3HZ2 A; 
#chains in the Genus database with same CATH homology
 4EL6 A;  1ELP A;  4GR7 A;  1OKI A;  1AG4 A;  1A7H A;  1GCS A;  3QK3 A;  1ZIQ A;  1HA4 A;  4W9A A;  3ENU A;  2JDF A;  2M3C A;  4GCR A;  4IAU A;  3SNY A;  1GAM A;  1ZIR A;  1ZGT A;  2B1O A;  1AMM A;  3SNZ A;  1NPS A;  3HZB A;  1A5D A;  3SO0 A;  5HT9 A;  1ZWO A;  2KP5 A;  3LWK A;  4JGF A;  2DAD A;  4AKA A;  1ZIE A;  2M3T A;  3SO1 A;  1E7N A;  2A5M A;  2G98 A;  1HK0 X;  1DSL A;  2BV2 A;  2K1W A;  2KFB A;  2NBR A;  5HT8 A;  1BD7 A;  1I5I A;  1BLB A;  1M8U A;  1A45 A;  4W9B A;  1ZWM A;  2K1X A;  1HDF A;  2M3U A;  4PSP A;  2V2U A;  4FD9 A;  4NI3 A;  1PRS A;  2JDG A;  3ENT A;  1PRR A;  3I9H A;  3CW3 A;  3IAJ A;  2BB2 A;  1H4A X;  1YTQ A;  4PSR A;  1YHP A;  3HZ2 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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4JGFA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations