4PNK | Genus

Total Genus 15

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	15
sequence length	62
structure length	62
Chain Sequence	ASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFS

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 62 atoms

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62 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Identification and structure-function analysis of subfamily selective g protein-coupled receptor kinase inhibitors. pubmed doi rcsb
molecule keywords	Beta-adrenergic receptor kinase 1
molecule tags	Transferase/transferase inhibitor
source organism	Homo sapiens
total genus	15
structure length	62
sequence length	62
ec nomenclature
pdb deposition date	2014-05-23

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
G	PF00631	G-gamma	GGL domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
4.10.260.10	Few Secondary Structures	Irregular	G Protein Gi Gamma 2	Transducin (heterotrimeric G protein), gamma chain	4pnkG00

3V5WG 1B9XB 3AH8G 1B9YB 1XHMB 5HE1G 5HE3G 3KRWG 1GP2G 5TDHG 2PBIA 4PNKG 5HE0G 1TBGE 5HE2G 3CIKG 1GG2G 1GOTG 3KRXG 3PVUG 3PSCG 4MK0G 1OMWG 5KDOG 2TRCG 4KFMG 1A0RG 3SN6G 3PVWG 2BCJG
chains in the Genus database with same CATH superfamily

3V5WG 1B9XB 3AH8G 1B9YB 1XHMB 5HE1G 5HE3G 3KRWG 1GP2G 5TDHG 2PBIA 4PNKG 1HFES 5HE0G 1TBGE 5HE2G 3CIKG 1GG2G 1GOTG 3KRXG 3PVUG 3PSCG 4MK0G 1OMWG 5KDOG 2TRCG 4KFMG 1A0RG 3SN6G 1IOJA 3PVWG 2BCJG
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3V5W G;  1B9X B;  3AH8 G;  1B9Y B;  1XHM B;  5HE1 G;  5HE3 G;  3KRW G;  1GP2 G;  5TDH G;  2PBI A;  4PNK G;  5HE0 G;  1TBG E;  5HE2 G;  3CIK G;  1GG2 G;  1GOT G;  3KRX G;  3PVU G;  3PSC G;  4MK0 G;  1OMW G;  5KDO G;  2TRC G;  4KFM G;  1A0R G;  3SN6 G;  3PVW G;  2BCJ G; 
#chains in the Genus database with same CATH topology
 3V5W G;  1B9X B;  3AH8 G;  1B9Y B;  1XHM B;  5HE1 G;  5HE3 G;  3KRW G;  1GP2 G;  5TDH G;  2PBI A;  4PNK G;  1HFE S;  5HE0 G;  1TBG E;  5HE2 G;  3CIK G;  1GG2 G;  1GOT G;  3KRX G;  3PVU G;  3PSC G;  4MK0 G;  1OMW G;  5KDO G;  2TRC G;  4KFM G;  1A0R G;  3SN6 G;  1IOJ A;  3PVW G;  2BCJ G; 
#chains in the Genus database with same CATH homology
 3V5W G;  1B9X B;  3AH8 G;  1B9Y B;  1XHM B;  5HE1 G;  5HE3 G;  3KRW G;  1GP2 G;  5TDH G;  2PBI A;  4PNK G;  5HE0 G;  1TBG E;  5HE2 G;  3CIK G;  1GG2 G;  1GOT G;  3KRX G;  3PVU G;  3PSC G;  4MK0 G;  1OMW G;  5KDO G;  2TRC G;  4KFM G;  1A0R G;  3SN6 G;  3PVW G;  2BCJ G;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4PNKG

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations