4PNKG

G protein-coupled receptor kinase 2 in complex with gsk180736a
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
62
structure length
62
Chain Sequence
ASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification and structure-function analysis of subfamily selective g protein-coupled receptor kinase inhibitors.
pubmed doi rcsb
molecule keywords Beta-adrenergic receptor kinase 1
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
total genus 15
structure length 62
sequence length 62
ec nomenclature
pdb deposition date 2014-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
G PF00631 G-gamma GGL domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 4pnkG00
3PVWG 3PSCG 4KFMG 1B9XB 3CIKG 1GOTG 3KRXG 1GP2G 3PVUG 3KRWG 1OMWG 1A0RG 3AH8G 5KDOG 1B9YB 5HE2G 2TRCG 5HE0G 3SN6G 1TBGE 2PBIA 1GG2G 2BCJG 5HE1G 5TDHG 3V5WG 4MK0G 5HE3G 4PNKG 1XHMB
chains in the Genus database with same CATH superfamily
3PVWG 3PSCG 4KFMG 1B9XB 3CIKG 1GOTG 3KRXG 1GP2G 3PVUG 3KRWG 1OMWG 1A0RG 1IOJA 3AH8G 5KDOG 1B9YB 5HE2G 2TRCG 5HE0G 3SN6G 1TBGE 2PBIA 1GG2G 2BCJG 1HFES 5HE1G 5TDHG 3V5WG 4MK0G 5HE3G 4PNKG 1XHMB
chains in the Genus database with same CATH topology
3PVWG 3PSCG 4KFMG 1B9XB 3CIKG 1GOTG 3KRXG 1GP2G 3PVUG 3KRWG 1OMWG 1A0RG 3AH8G 5KDOG 1B9YB 5HE2G 2TRCG 5HE0G 3SN6G 1TBGE 2PBIA 1GG2G 2BCJG 5HE1G 5TDHG 3V5WG 4MK0G 5HE3G 4PNKG 1XHMB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PVW G;  3PSC G;  4KFM G;  1B9X B;  3CIK G;  1GOT G;  3KRX G;  1GP2 G;  3PVU G;  3KRW G;  1OMW G;  1A0R G;  3AH8 G;  5KDO G;  1B9Y B;  5HE2 G;  2TRC G;  5HE0 G;  3SN6 G;  1TBG E;  2PBI A;  1GG2 G;  2BCJ G;  5HE1 G;  5TDH G;  3V5W G;  4MK0 G;  5HE3 G;  4PNK G;  1XHM B; 
#chains in the Genus database with same CATH topology
 3PVW G;  3PSC G;  4KFM G;  1B9X B;  3CIK G;  1GOT G;  3KRX G;  1GP2 G;  3PVU G;  3KRW G;  1OMW G;  1A0R G;  1IOJ A;  3AH8 G;  5KDO G;  1B9Y B;  5HE2 G;  2TRC G;  5HE0 G;  3SN6 G;  1TBG E;  2PBI A;  1GG2 G;  2BCJ G;  1HFE S;  5HE1 G;  5TDH G;  3V5W G;  4MK0 G;  5HE3 G;  4PNK G;  1XHM B; 
#chains in the Genus database with same CATH homology
 3PVW G;  3PSC G;  4KFM G;  1B9X B;  3CIK G;  1GOT G;  3KRX G;  1GP2 G;  3PVU G;  3KRW G;  1OMW G;  1A0R G;  3AH8 G;  5KDO G;  1B9Y B;  5HE2 G;  2TRC G;  5HE0 G;  3SN6 G;  1TBG E;  2PBI A;  1GG2 G;  2BCJ G;  5HE1 G;  5TDH G;  3V5W G;  4MK0 G;  5HE3 G;  4PNK G;  1XHM B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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