4GX7A

Vibrio cholerae cytolysin beta-prism domain with methyl-alpha-mannose bound
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
132
structure length
132
Chain Sequence
MSSPILGYTQGKMNQQRVGQDNRLYVRAGAAIDALGSASDLLVGGNGGSLSSVDLSGVKSITATSGDFQYGGQQLVALTFTYQDGRQQTVGSKAYVTNAHEDRFDLPDAAKITQLKIWADDWLVKGVQFDLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Vibrio cholerae Cytolysin Recognizes the Heptasaccharide Core of Complex N-Glycans with Nanomolar Affinity.
pubmed doi rcsb
molecule tags Toxin
source organism Vibrio cholerae
molecule keywords Cytolysin and hemolysin HlyA Pore-forming toxin
total genus 27
structure length 132
sequence length 132
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2012-09-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16458 Beta-prism_lec Beta-prism lectin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.100.10.30 Mainly Beta Aligned Prism Vitelline Membrane Outer Layer Protein I, subunit A Jacalin-like lectin domain 4gx7A00
1C3MA 4PITA 1VBPA 4R6QA 1JACA 3APAA 1C3NA 4AK4A 2BMZA 1UGXA 4WOGA 3MITA 4MQ0A 1KU8A 2NUOA 1WS4C 1UGWA 1KUJA 1WS5C 3VY7A 5J4TA 3LL2A 2GUCA 3VY6A 1M26A 3VZEA 2HYQA 5BN6E 3LLYA 3R50A 4R6PA 5EXGA 4PIKA 1UGYA 3VZFA 1WS4A 4R6NA 1JOTA 3LL1A 4GX7A 1TOQA 4PIFA 4PIUA 5AV7A 3VZGA 1XEZA 1TP8A 1XXRA 1PXDA 1X1VA 2HYRA 1ZGRA 2GUEA 2JZ4A 3R52A 1J4TA 2BN0A 1UH1A 1C3KA 4AKCA 2GUXA 3LM1A 1UH0A 2GTYA 3WOBA 3AQGA 4R6RA 1WS5A 3P8SA 3WOCA 3MIUA 3R51A 3O44A 1XXQA 4DDNA 1J4SA 1J4UA 5J50A 2NU5A 5J51A 3LL0A 2GUDA 3LKYA 4AKBA 5JM1A 3LLZA 2BMYA 1UGYC 5J4XA 1VBOA 1UGWC 4AKDA 1ZGSA 3MIVA 4R6OA 1OUWA
chains in the Genus database with same CATH superfamily
1C3MA 4PITA 4QX1A 1VBPA 4R6QA 1JACA 3APAA 1C3NA 4QX0A 4ARXA 4AK4A 2BMZA 1UGXA 1I5PA 4WOGA 3MITA 4MQ0A 1KU8A 2NUOA 4QX2A 1WS4C 1UGWA 1KUJA 1WS5C 3VY7A 4MOAA 5J4TA 3LL2A 2GUCA 3VY6A 1M26A 3VZEA 2HYQA 5BN6E 2C9KA 3LLYA 3R50A 4R6PA 4D8MA 1DLCA 5EXGA 3EB7A 4PIKA 1UGYA 3VZFA 1CIYA 1WS4A 1JOTA 3LL1A 4GX7A 4R6NA 1TOQA 4PIFA 4W8JA 4PIUA 5AV7A 3VZGA 1XEZA 1TP8A 3TOWA 1XXRA 1PXDA 1X1VA 2HYRA 1ZGRA 2GUEA 2JZ4A 3R52A 1J4TA 2BN0A 1UH1A 1C3KA 4AKCA 2GUXA 3LM1A 1UH0A 2GTYA 3WOBA 3AQGA 4R6RA 1WS5A 3P8SA 3WOCA 1JI6A 3MIUA 1W99A 3R51A 3O44A 1XXQA 4DDNA 1J4SA 1J4UA 5J50A 1VMOA 2NU5A 5J51A 3LL0A 2GUDA 3LKYA 4QX3A 4AKBA 5JM1A 3LLZA 2BMYA 1UGYC 5J4XA 1VBOA 4ARYA 1UGWC 4AKDA 1ZGSA 3MIVA 2QP2A 4R6OA 1OUWA
chains in the Genus database with same CATH topology
1C3MA 4PITA 1VBPA 4R6QA 1JACA 3APAA 1C3NA 4AK4A 2BMZA 1UGXA 4WOGA 3MITA 4MQ0A 1KU8A 2NUOA 1WS4C 1UGWA 1KUJA 1WS5C 3VY7A 5J4TA 3LL2A 2GUCA 3VY6A 1M26A 3VZEA 2HYQA 5BN6E 3LLYA 3R50A 4R6PA 5EXGA 4PIKA 1UGYA 3VZFA 1WS4A 4R6NA 1JOTA 3LL1A 4GX7A 1TOQA 4PIFA 4PIUA 5AV7A 3VZGA 1XEZA 1TP8A 1XXRA 1PXDA 1X1VA 2HYRA 1ZGRA 2GUEA 2JZ4A 3R52A 1J4TA 2BN0A 1UH1A 1C3KA 4AKCA 2GUXA 3LM1A 1UH0A 2GTYA 3WOBA 3AQGA 4R6RA 1WS5A 3P8SA 3WOCA 3MIUA 3R51A 3O44A 1XXQA 4DDNA 1J4SA 1J4UA 5J50A 2NU5A 5J51A 3LL0A 2GUDA 3LKYA 4AKBA 5JM1A 3LLZA 2BMYA 1UGYC 5J4XA 1VBOA 1UGWC 4AKDA 1ZGSA 3MIVA 4R6OA 1OUWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1C3M A;  4PIT A;  1VBP A;  4R6Q A;  1JAC A;  3APA A;  1C3N A;  4AK4 A;  2BMZ A;  1UGX A;  4WOG A;  3MIT A;  4MQ0 A;  1KU8 A;  2NUO A;  1WS4 C;  1UGW A;  1KUJ A;  1WS5 C;  3VY7 A;  5J4T A;  3LL2 A;  2GUC A;  3VY6 A;  1M26 A;  3VZE A;  2HYQ A;  5BN6 E;  3LLY A;  3R50 A;  4R6P A;  5EXG A;  4PIK A;  1UGY A;  3VZF A;  1WS4 A;  4R6N A;  1JOT A;  3LL1 A;  4GX7 A;  1TOQ A;  4PIF A;  4PIU A;  5AV7 A;  3VZG A;  1XEZ A;  1TP8 A;  1XXR A;  1PXD A;  1X1V A;  2HYR A;  1ZGR A;  2GUE A;  2JZ4 A;  3R52 A;  1J4T A;  2BN0 A;  1UH1 A;  1C3K A;  4AKC A;  2GUX A;  3LM1 A;  1UH0 A;  2GTY A;  3WOB A;  3AQG A;  4R6R A;  1WS5 A;  3P8S A;  3WOC A;  3MIU A;  3R51 A;  3O44 A;  1XXQ A;  4DDN A;  1J4S A;  1J4U A;  5J50 A;  2NU5 A;  5J51 A;  3LL0 A;  2GUD A;  3LKY A;  4AKB A;  5JM1 A;  3LLZ A;  2BMY A;  1UGY C;  5J4X A;  1VBO A;  1UGW C;  4AKD A;  1ZGS A;  3MIV A;  4R6O A;  1OUW A; 
#chains in the Genus database with same CATH topology
 1C3M A;  4PIT A;  4QX1 A;  1VBP A;  4R6Q A;  1JAC A;  3APA A;  1C3N A;  4QX0 A;  4ARX A;  4AK4 A;  2BMZ A;  1UGX A;  1I5P A;  4WOG A;  3MIT A;  4MQ0 A;  1KU8 A;  2NUO A;  4QX2 A;  1WS4 C;  1UGW A;  1KUJ A;  1WS5 C;  3VY7 A;  4MOA A;  5J4T A;  3LL2 A;  2GUC A;  3VY6 A;  1M26 A;  3VZE A;  2HYQ A;  5BN6 E;  2C9K A;  3LLY A;  3R50 A;  4R6P A;  4D8M A;  1DLC A;  5EXG A;  3EB7 A;  4PIK A;  1UGY A;  3VZF A;  1CIY A;  1WS4 A;  1JOT A;  3LL1 A;  4GX7 A;  4R6N A;  1TOQ A;  4PIF A;  4W8J A;  4PIU A;  5AV7 A;  3VZG A;  1XEZ A;  1TP8 A;  3TOW A;  1XXR A;  1PXD A;  1X1V A;  2HYR A;  1ZGR A;  2GUE A;  2JZ4 A;  3R52 A;  1J4T A;  2BN0 A;  1UH1 A;  1C3K A;  4AKC A;  2GUX A;  3LM1 A;  1UH0 A;  2GTY A;  3WOB A;  3AQG A;  4R6R A;  1WS5 A;  3P8S A;  3WOC A;  1JI6 A;  3MIU A;  1W99 A;  3R51 A;  3O44 A;  1XXQ A;  4DDN A;  1J4S A;  1J4U A;  5J50 A;  1VMO A;  2NU5 A;  5J51 A;  3LL0 A;  2GUD A;  3LKY A;  4QX3 A;  4AKB A;  5JM1 A;  3LLZ A;  2BMY A;  1UGY C;  5J4X A;  1VBO A;  4ARY A;  1UGW C;  4AKD A;  1ZGS A;  3MIV A;  2QP2 A;  4R6O A;  1OUW A; 
#chains in the Genus database with same CATH homology
 1C3M A;  4PIT A;  1VBP A;  4R6Q A;  1JAC A;  3APA A;  1C3N A;  4AK4 A;  2BMZ A;  1UGX A;  4WOG A;  3MIT A;  4MQ0 A;  1KU8 A;  2NUO A;  1WS4 C;  1UGW A;  1KUJ A;  1WS5 C;  3VY7 A;  5J4T A;  3LL2 A;  2GUC A;  3VY6 A;  1M26 A;  3VZE A;  2HYQ A;  5BN6 E;  3LLY A;  3R50 A;  4R6P A;  5EXG A;  4PIK A;  1UGY A;  3VZF A;  1WS4 A;  4R6N A;  1JOT A;  3LL1 A;  4GX7 A;  1TOQ A;  4PIF A;  4PIU A;  5AV7 A;  3VZG A;  1XEZ A;  1TP8 A;  1XXR A;  1PXD A;  1X1V A;  2HYR A;  1ZGR A;  2GUE A;  2JZ4 A;  3R52 A;  1J4T A;  2BN0 A;  1UH1 A;  1C3K A;  4AKC A;  2GUX A;  3LM1 A;  1UH0 A;  2GTY A;  3WOB A;  3AQG A;  4R6R A;  1WS5 A;  3P8S A;  3WOC A;  3MIU A;  3R51 A;  3O44 A;  1XXQ A;  4DDN A;  1J4S A;  1J4U A;  5J50 A;  2NU5 A;  5J51 A;  3LL0 A;  2GUD A;  3LKY A;  4AKB A;  5JM1 A;  3LLZ A;  2BMY A;  1UGY C;  5J4X A;  1VBO A;  1UGW C;  4AKD A;  1ZGS A;  3MIV A;  4R6O A;  1OUW A; 
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similar chains in the Genus database (?% sequence similarity)
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