4H10B

Intermolecular recognition revealed by the complex structure of human clock-bmal1 basic helix-loop-helix domains with e-box dna
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
63
structure length
63
Chain Sequence
KDKAKRVSRNKSEKKRRDQFNVLIKELGSMLPGNARKMDKSTVLQKSIDFLRKHKEITAWLEH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic helix-loop-helix domains with E-box DNA.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords Aryl hydrocarbon receptor nuclear translocator-like protein
total genus 24
structure length 63
sequence length 63
ec nomenclature ec 2.3.1.48: Histone acetyltransferase.
pdb deposition date 2012-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 4h10B00
4F3LB 2YPAB 1UKLC 2QL2A 2QL2B 5I50A 4ATKA 2MH3A 2YPAA 4ATHA 1NKPA 3U5VA 1NKPB 1HLOA 1AM9A 3MUJA 5EYOA 2YPBA 2YPBB 4ATIA 1A0AA 4H10A 5I4ZA 4H10B 1AN4A 1MDYB 1NLWA 1NLWB 2LFHA 1AN2A 4AYAA 1MDYA 4F3LA 1R05A
chains in the Genus database with same CATH superfamily
4F3LB 2YPAB 1UKLC 2QL2A 2QL2B 5I50A 4ATKA 2MH3A 2YPAA 4ATHA 1NKPA 3U5VA 1NKPB 1HLOA 1AM9A 3MUJA 5EYOA 2YPBA 2YPBB 4ATIA 1A0AA 1ZZAA 1K1FA 5I4ZA 4H10A 4H10B 1AN4A 1MDYB 1NLWA 1NLWB 2LFHA 1AN2A 4AYAA 1MDYA 4F3LA 1R05A
chains in the Genus database with same CATH topology
4F3LB 2YPAB 1UKLC 2QL2A 2QL2B 5I50A 4ATKA 2MH3A 2YPAA 4ATHA 1NKPA 3U5VA 1NKPB 1HLOA 1AM9A 3MUJA 5EYOA 2YPBA 2YPBB 4ATIA 1A0AA 4H10A 5I4ZA 4H10B 1AN4A 1MDYB 1NLWA 1NLWB 2LFHA 1AN2A 4AYAA 1MDYA 4F3LA 1R05A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4F3L B;  2YPA B;  1UKL C;  2QL2 A;  2QL2 B;  5I50 A;  4ATK A;  2MH3 A;  2YPA A;  4ATH A;  1NKP A;  3U5V A;  1NKP B;  1HLO A;  1AM9 A;  3MUJ A;  5EYO A;  2YPB A;  2YPB B;  4ATI A;  1A0A A;  4H10 A;  5I4Z A;  4H10 B;  1AN4 A;  1MDY B;  1NLW A;  1NLW B;  2LFH A;  1AN2 A;  4AYA A;  1MDY A;  4F3L A;  1R05 A; 
#chains in the Genus database with same CATH topology
 4F3L B;  2YPA B;  1UKL C;  2QL2 A;  2QL2 B;  5I50 A;  4ATK A;  2MH3 A;  2YPA A;  4ATH A;  1NKP A;  3U5V A;  1NKP B;  1HLO A;  1AM9 A;  3MUJ A;  5EYO A;  2YPB A;  2YPB B;  4ATI A;  1A0A A;  1ZZA A;  1K1F A;  5I4Z A;  4H10 A;  4H10 B;  1AN4 A;  1MDY B;  1NLW A;  1NLW B;  2LFH A;  1AN2 A;  4AYA A;  1MDY A;  4F3L A;  1R05 A; 
#chains in the Genus database with same CATH homology
 4F3L B;  2YPA B;  1UKL C;  2QL2 A;  2QL2 B;  5I50 A;  4ATK A;  2MH3 A;  2YPA A;  4ATH A;  1NKP A;  3U5V A;  1NKP B;  1HLO A;  1AM9 A;  3MUJ A;  5EYO A;  2YPB A;  2YPB B;  4ATI A;  1A0A A;  4H10 A;  5I4Z A;  4H10 B;  1AN4 A;  1MDY B;  1NLW A;  1NLW B;  2LFH A;  1AN2 A;  4AYA A;  1MDY A;  4F3L A;  1R05 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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