4PNKG

G protein-coupled receptor kinase 2 in complex with gsk180736a
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
62
structure length
62
Chain Sequence
ASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification and structure-function analysis of subfamily selective g protein-coupled receptor kinase inhibitors.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
molecule keywords Beta-adrenergic receptor kinase 1
total genus 15
structure length 62
sequence length 62
ec nomenclature
pdb deposition date 2014-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
G PF00631 G-gamma GGL domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 4pnkG00
3AH8G 5HE0G 2PBIA 3KRXG 4MK0G 1OMWG 4PNKG 1A0RG 5HE3G 1TBGE 5HE2G 1GP2G 1GOTG 1GG2G 5HE1G 2BCJG 3KRWG 3CIKG 5TDHG 3V5WG 3PVUG 1XHMB 5KDOG 1B9YB 4KFMG 3PSCG 3SN6G 3PVWG 2TRCG 1B9XB
chains in the Genus database with same CATH superfamily
3AH8G 5HE0G 2PBIA 3KRXG 4MK0G 1OMWG 4PNKG 1A0RG 5HE3G 1TBGE 5HE2G 1IOJA 1GP2G 1GOTG 1GG2G 5HE1G 2BCJG 3KRWG 3CIKG 5TDHG 3V5WG 3PVUG 1XHMB 5KDOG 1B9YB 4KFMG 3PSCG 3SN6G 3PVWG 1HFES 2TRCG 1B9XB
chains in the Genus database with same CATH topology
3AH8G 5HE0G 2PBIA 3KRXG 4MK0G 1OMWG 4PNKG 1A0RG 5HE3G 1TBGE 5HE2G 1GP2G 1GOTG 1GG2G 5HE1G 2BCJG 3KRWG 3CIKG 5TDHG 3V5WG 3PVUG 1XHMB 5KDOG 1B9YB 4KFMG 3PSCG 3SN6G 3PVWG 2TRCG 1B9XB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AH8 G;  5HE0 G;  2PBI A;  3KRX G;  4MK0 G;  1OMW G;  4PNK G;  1A0R G;  5HE3 G;  1TBG E;  5HE2 G;  1GP2 G;  1GOT G;  1GG2 G;  5HE1 G;  2BCJ G;  3KRW G;  3CIK G;  5TDH G;  3V5W G;  3PVU G;  1XHM B;  5KDO G;  1B9Y B;  4KFM G;  3PSC G;  3SN6 G;  3PVW G;  2TRC G;  1B9X B; 
#chains in the Genus database with same CATH topology
 3AH8 G;  5HE0 G;  2PBI A;  3KRX G;  4MK0 G;  1OMW G;  4PNK G;  1A0R G;  5HE3 G;  1TBG E;  5HE2 G;  1IOJ A;  1GP2 G;  1GOT G;  1GG2 G;  5HE1 G;  2BCJ G;  3KRW G;  3CIK G;  5TDH G;  3V5W G;  3PVU G;  1XHM B;  5KDO G;  1B9Y B;  4KFM G;  3PSC G;  3SN6 G;  3PVW G;  1HFE S;  2TRC G;  1B9X B; 
#chains in the Genus database with same CATH homology
 3AH8 G;  5HE0 G;  2PBI A;  3KRX G;  4MK0 G;  1OMW G;  4PNK G;  1A0R G;  5HE3 G;  1TBG E;  5HE2 G;  1GP2 G;  1GOT G;  1GG2 G;  5HE1 G;  2BCJ G;  3KRW G;  3CIK G;  5TDH G;  3V5W G;  3PVU G;  1XHM B;  5KDO G;  1B9Y B;  4KFM G;  3PSC G;  3SN6 G;  3PVW G;  2TRC G;  1B9X B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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