5DQEA

Crystal structure of human transcription factor tead2 in complex with bromo-fenamic acid
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
225
structure length
193
Chain Sequence
GLGTARLQLVEFSAFVEPQRHLFVHISQLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERGAQHHIYRLVR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic Strategy.
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords Transcriptional enhancer factor TEF-4
total genus 47
structure length 193
sequence length 225
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF17725 YBD YAP binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.50.80 Mainly Beta Distorted Sandwich Coagulation Factor XIII; Chain A, domain 1 Coagulation Factor XIII; Chain A, domain 1 5dqeA00
3JUAA 5EMVA 3KYSA 5HGUA 5EMWA 4RE1A 4LN0A 5DQEA 3L15A 5DQ8A
chains in the Genus database with same CATH superfamily
4MAHA 4ALEA 3GQQA 4EISB 4GOKC 5L7KA 2YOYA 2VTCA 4FMRA 5E80A 4ALRA 1FSTA 5EMWA 2JI0A 5EMVA 3T5IA 2JHWA 1KSJB 2BXWA 5ACJA 5TB5B 4OY8A 5HNOA 4ALTA 4JV8B 2BENA 4MAIA 2LHSA 1HH4D 2JHZA 4ALQA 3RBQA 4D7UA 1KMTA 1DOAB 5AA7A 1FT3A 5DQ8A 4JVFB 2R5OA 5FTZA 4JVBB 4A02A 4D7VA 4RE1A 5ACHA 5ACGA 5DQEA 2JHYA 4JHPB 5ACFA 3EIIA 4EISA 3EJAA 2JHTA 5IJUA 4JV6B 1RHOA 5F2UA 1FT0A 2XWXA 1KSGB 4EIRA 1GDFA 1AJWA 1KSHB 2YETA 4F38B 5E8FA 1QVYA 3ZUDA 3L15A 4B5QA 4QI8A 5HNPA 5HGUA 3T5GB 1FSOA 5FOHA 4GOJC 3UAMA 2YOXA 4ALCA 2YOWA 2BEMA 4GBOA 5ACIA 4OY6A 1DS6B 3JUAA 2JHUA 3KYSA 4ALSA 2JHSA 4LN0A 2JHXA 4OY7A 2JHVA 5TARB 5FJQA
chains in the Genus database with same CATH topology
4MAHA 5ACGA 3ZUDA 4EISB 5DQEA 3L15A 4B5QA 4MAIA 4QI8A 5ACFA 2VTCA 4FMRA 5HGUA 3EIIA 5EMWA 4EISA 3EJAA 5FOHA 4D7UA 5EMVA 5ACIA 5DQ8A 4EIRA 5ACJA 3JUAA 4D7VA 3KYSA 4RE1A 4LN0A 5ACHA 2YETA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3JUA A;  5EMV A;  3KYS A;  5HGU A;  5EMW A;  4RE1 A;  4LN0 A;  5DQE A;  3L15 A;  5DQ8 A; 
#chains in the Genus database with same CATH topology
 4MAH A;  4ALE A;  3GQQ A;  4EIS B;  4GOK C;  5L7K A;  2YOY A;  2VTC A;  4FMR A;  5E80 A;  4ALR A;  1FST A;  5EMW A;  2JI0 A;  5EMV A;  3T5I A;  2JHW A;  1KSJ B;  2BXW A;  5ACJ A;  5TB5 B;  4OY8 A;  5HNO A;  4ALT A;  4JV8 B;  2BEN A;  4MAI A;  2LHS A;  1HH4 D;  2JHZ A;  4ALQ A;  3RBQ A;  4D7U A;  1KMT A;  1DOA B;  5AA7 A;  1FT3 A;  5DQ8 A;  4JVF B;  2R5O A;  5FTZ A;  4JVB B;  4A02 A;  4D7V A;  4RE1 A;  5ACH A;  5ACG A;  5DQE A;  2JHY A;  4JHP B;  5ACF A;  3EII A;  4EIS A;  3EJA A;  2JHT A;  5IJU A;  4JV6 B;  1RHO A;  5F2U A;  1FT0 A;  2XWX A;  1KSG B;  4EIR A;  1GDF A;  1AJW A;  1KSH B;  2YET A;  4F38 B;  5E8F A;  1QVY A;  3ZUD A;  3L15 A;  4B5Q A;  4QI8 A;  5HNP A;  5HGU A;  3T5G B;  1FSO A;  5FOH A;  4GOJ C;  3UAM A;  2YOX A;  4ALC A;  2YOW A;  2BEM A;  4GBO A;  5ACI A;  4OY6 A;  1DS6 B;  3JUA A;  2JHU A;  3KYS A;  4ALS A;  2JHS A;  4LN0 A;  2JHX A;  4OY7 A;  2JHV A;  5TAR B;  5FJQ A; 
#chains in the Genus database with same CATH homology
 4MAH A;  5ACG A;  3ZUD A;  4EIS B;  5DQE A;  3L15 A;  4B5Q A;  4MAI A;  4QI8 A;  5ACF A;  2VTC A;  4FMR A;  5HGU A;  3EII A;  5EMW A;  4EIS A;  3EJA A;  5FOH A;  4D7U A;  5EMV A;  5ACI A;  5DQ8 A;  4EIR A;  5ACJ A;  3JUA A;  4D7V A;  3KYS A;  4RE1 A;  4LN0 A;  5ACH A;  2YET A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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