5EYOA

The crystal structure of the max bhlh domain in complex with 5-carboxyl cytosine dna
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
87
structure length
87
Chain Sequence
HMADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords Protein max
total genus 37
structure length 87
sequence length 87
chains with identical sequence C
ec nomenclature
pdb deposition date 2015-11-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 5eyoA00
2YPAA 1NLWB 3MUJA 2QL2B 4ATKA 1NKPB 1NLWA 4ATIA 4H10B 2QL2A 1AM9A 1NKPA 5I4ZA 2MH3A 5EYOA 1AN2A 4AYAA 4H10A 1A0AA 1MDYB 1UKLC 2YPBB 1MDYA 3U5VA 1HLOA 1AN4A 4F3LB 2YPBA 2LFHA 4ATHA 2YPAB 1R05A 4F3LA 5I50A
chains in the Genus database with same CATH superfamily
2YPAA 1NLWB 3MUJA 1ZZAA 2QL2B 4ATKA 1NKPB 1NLWA 4ATIA 4H10B 2QL2A 1AM9A 1NKPA 5I4ZA 2MH3A 5EYOA 1AN2A 4AYAA 4H10A 1A0AA 1MDYB 1K1FA 1UKLC 2YPBB 1MDYA 3U5VA 1HLOA 1AN4A 4F3LB 2YPBA 2LFHA 4ATHA 2YPAB 1R05A 4F3LA 5I50A
chains in the Genus database with same CATH topology
2YPAA 1NLWB 3MUJA 2QL2B 4ATKA 1NKPB 1NLWA 4ATIA 4H10B 2QL2A 1AM9A 1NKPA 5I4ZA 2MH3A 5EYOA 1AN2A 4AYAA 4H10A 1A0AA 1MDYB 1UKLC 2YPBB 1MDYA 3U5VA 1HLOA 1AN4A 4F3LB 2YPBA 2LFHA 4ATHA 2YPAB 1R05A 4F3LA 5I50A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YPA A;  1NLW B;  3MUJ A;  2QL2 B;  4ATK A;  1NKP B;  1NLW A;  4ATI A;  4H10 B;  2QL2 A;  1AM9 A;  1NKP A;  5I4Z A;  2MH3 A;  5EYO A;  1AN2 A;  4AYA A;  4H10 A;  1A0A A;  1MDY B;  1UKL C;  2YPB B;  1MDY A;  3U5V A;  1HLO A;  1AN4 A;  4F3L B;  2YPB A;  2LFH A;  4ATH A;  2YPA B;  1R05 A;  4F3L A;  5I50 A; 
#chains in the Genus database with same CATH topology
 2YPA A;  1NLW B;  3MUJ A;  1ZZA A;  2QL2 B;  4ATK A;  1NKP B;  1NLW A;  4ATI A;  4H10 B;  2QL2 A;  1AM9 A;  1NKP A;  5I4Z A;  2MH3 A;  5EYO A;  1AN2 A;  4AYA A;  4H10 A;  1A0A A;  1MDY B;  1K1F A;  1UKL C;  2YPB B;  1MDY A;  3U5V A;  1HLO A;  1AN4 A;  4F3L B;  2YPB A;  2LFH A;  4ATH A;  2YPA B;  1R05 A;  4F3L A;  5I50 A; 
#chains in the Genus database with same CATH homology
 2YPA A;  1NLW B;  3MUJ A;  2QL2 B;  4ATK A;  1NKP B;  1NLW A;  4ATI A;  4H10 B;  2QL2 A;  1AM9 A;  1NKP A;  5I4Z A;  2MH3 A;  5EYO A;  1AN2 A;  4AYA A;  4H10 A;  1A0A A;  1MDY B;  1UKL C;  2YPB B;  1MDY A;  3U5V A;  1HLO A;  1AN4 A;  4F3L B;  2YPB A;  2LFH A;  4ATH A;  2YPA B;  1R05 A;  4F3L A;  5I50 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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