5F2UA

Structure of fully modified farnesylated inpp5e peptide in complex with pde6d
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
149
structure length
149
Chain Sequence
SAKDERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSTEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLLVSTSRVRLFYV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title PDE6delta-mediated sorting of INPP5E into the cilium is determined by cargo-carrier affinity.
pubmed doi rcsb
molecule tags Lipid binding protein
source organism Homo sapiens
molecule keywords Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodie
total genus 48
structure length 149
sequence length 149
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF05351 GMP_PDE_delta GMP-PDE, delta subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.50.40 Mainly Beta Distorted Sandwich Coagulation Factor XIII; Chain A, domain 1 GMP phosphodiesterase, delta subunit 5f2uA00
5TB5B 1KSJB 4JV8B 1KSGB 5L7KA 3T5IA 3GQQA 5TARB 1KSHB 5F2UA 4JV6B 4JVBB 4JVFB 4GOJC 5E8FA 4JHPB 3RBQA 3T5GB 5E80A 4GOKC
chains in the Genus database with same CATH superfamily
1FT3A 4A02A 4FMRA 5ACIA 4ALTA 5IJUA 4D7VA 4F38B 5HNOA 2LHSA 2XWXA 1QVYA 3L15A 4ALSA 5E8FA 1FT0A 5FJQA 4GBOA 4MAIA 1KSGB 3ZUDA 3GQQA 5TARB 5EMVA 2JHSA 4JV6B 4JVBB 3UAMA 1DOAB 2JHYA 2JHTA 3RBQA 2YOWA 3T5GB 2BEMA 5DQEA 2VTCA 4B5QA 2BENA 5TB5B 4EISA 4OY6A 2JHUA 4JV8B 4ALRA 3JUAA 1HH4D 5F2UA 5FOHA 4EISB 2JI0A 5HNPA 4JVFB 4MAHA 4ALQA 2JHXA 5DQ8A 1FSOA 4OY8A 4GOJC 5EMWA 2YETA 2JHZA 4QI8A 2JHVA 1GDFA 5AA7A 2BXWA 3KYSA 5E80A 2YOXA 1KMTA 5HGUA 4GOKC 5ACGA 4D7UA 4OY7A 3EJAA 1KSJB 5L7KA 4LN0A 3T5IA 3EIIA 2R5OA 4EIRA 2YOYA 2JHWA 4ALCA 5ACJA 5FTZA 5ACFA 1DS6B 1RHOA 1AJWA 1FSTA 4JHPB 5ACHA 4ALEA 4RE1A 1KSHB
chains in the Genus database with same CATH topology
5TB5B 1KSJB 4JV8B 1KSGB 5L7KA 3T5IA 3GQQA 5TARB 1KSHB 5F2UA 4JV6B 4JVBB 4JVFB 4GOJC 5E8FA 4JHPB 3RBQA 3T5GB 5E80A 4GOKC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5TB5 B;  1KSJ B;  4JV8 B;  1KSG B;  5L7K A;  3T5I A;  3GQQ A;  5TAR B;  1KSH B;  5F2U A;  4JV6 B;  4JVB B;  4JVF B;  4GOJ C;  5E8F A;  4JHP B;  3RBQ A;  3T5G B;  5E80 A;  4GOK C; 
#chains in the Genus database with same CATH topology
 1FT3 A;  4A02 A;  4FMR A;  5ACI A;  4ALT A;  5IJU A;  4D7V A;  4F38 B;  5HNO A;  2LHS A;  2XWX A;  1QVY A;  3L15 A;  4ALS A;  5E8F A;  1FT0 A;  5FJQ A;  4GBO A;  4MAI A;  1KSG B;  3ZUD A;  3GQQ A;  5TAR B;  5EMV A;  2JHS A;  4JV6 B;  4JVB B;  3UAM A;  1DOA B;  2JHY A;  2JHT A;  3RBQ A;  2YOW A;  3T5G B;  2BEM A;  5DQE A;  2VTC A;  4B5Q A;  2BEN A;  5TB5 B;  4EIS A;  4OY6 A;  2JHU A;  4JV8 B;  4ALR A;  3JUA A;  1HH4 D;  5F2U A;  5FOH A;  4EIS B;  2JI0 A;  5HNP A;  4JVF B;  4MAH A;  4ALQ A;  2JHX A;  5DQ8 A;  1FSO A;  4OY8 A;  4GOJ C;  5EMW A;  2YET A;  2JHZ A;  4QI8 A;  2JHV A;  1GDF A;  5AA7 A;  2BXW A;  3KYS A;  5E80 A;  2YOX A;  1KMT A;  5HGU A;  4GOK C;  5ACG A;  4D7U A;  4OY7 A;  3EJA A;  1KSJ B;  5L7K A;  4LN0 A;  3T5I A;  3EII A;  2R5O A;  4EIR A;  2YOY A;  2JHW A;  4ALC A;  5ACJ A;  5FTZ A;  5ACF A;  1DS6 B;  1RHO A;  1AJW A;  1FST A;  4JHP B;  5ACH A;  4ALE A;  4RE1 A;  1KSH B; 
#chains in the Genus database with same CATH homology
 5TB5 B;  1KSJ B;  4JV8 B;  1KSG B;  5L7K A;  3T5I A;  3GQQ A;  5TAR B;  1KSH B;  5F2U A;  4JV6 B;  4JVB B;  4JVF B;  4GOJ C;  5E8F A;  4JHP B;  3RBQ A;  3T5G B;  5E80 A;  4GOK C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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