5F2UA

Structure of fully modified farnesylated inpp5e peptide in complex with pde6d
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
149
structure length
149
Chain Sequence
SAKDERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSTEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLLVSTSRVRLFYV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title PDE6delta-mediated sorting of INPP5E into the cilium is determined by cargo-carrier affinity.
pubmed doi rcsb
molecule tags Lipid binding protein
source organism Homo sapiens
molecule keywords Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodie
total genus 48
structure length 149
sequence length 149
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF05351 GMP_PDE_delta GMP-PDE, delta subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.50.40 Mainly Beta Distorted Sandwich Coagulation Factor XIII; Chain A, domain 1 GMP phosphodiesterase, delta subunit 5f2uA00
1KSJB 1KSHB 3RBQA 4JV6B 5TB5B 4GOKC 3GQQA 4JHPB 5TARB 5E8FA 3T5GB 5L7KA 5E80A 1KSGB 4GOJC 4JVFB 5F2UA 4JVBB 4JV8B 3T5IA
chains in the Genus database with same CATH superfamily
3ZUDA 3RBQA 4B5QA 5TB5B 4OY8A 2YOYA 5FTZA 2LHSA 5TARB 3T5GB 3EJAA 5L7KA 1AJWA 2JHZA 5IJUA 3KYSA 2YETA 4OY6A 5ACFA 4ALRA 2VTCA 5EMVA 1FT3A 5DQEA 4ALTA 3JUAA 4FMRA 1HH4D 1KSHB 2JHUA 4GBOA 2JHVA 2JI0A 5E8FA 4EISA 4ALSA 2BENA 5E80A 1FT0A 1KSGB 2R5OA 4ALCA 5F2UA 4A02A 2BXWA 4F38B 2BEMA 4JV8B 4QI8A 3T5IA 5EMWA 1KSJB 4ALEA 4RE1A 1RHOA 4GOKC 3GQQA 1DOAB 4JHPB 4EISB 5ACIA 2JHTA 2XWXA 1QVYA 1KMTA 5AA7A 1FSOA 2JHSA 2YOWA 4GOJC 3EIIA 4JVBB 3UAMA 3L15A 2JHYA 5FJQA 5ACJA 1FSTA 4JV6B 4LN0A 4D7VA 5DQ8A 2JHWA 5HGUA 4MAHA 4EIRA 5ACHA 4D7UA 4ALQA 5HNOA 1GDFA 4JVFB 5ACGA 5HNPA 1DS6B 4MAIA 5FOHA 4OY7A 2YOXA 2JHXA
chains in the Genus database with same CATH topology
1KSJB 1KSHB 3RBQA 4JV6B 5TB5B 4GOKC 3GQQA 4JHPB 5TARB 5E8FA 3T5GB 5L7KA 5E80A 1KSGB 4GOJC 4JVFB 5F2UA 4JVBB 4JV8B 3T5IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KSJ B;  1KSH B;  3RBQ A;  4JV6 B;  5TB5 B;  4GOK C;  3GQQ A;  4JHP B;  5TAR B;  5E8F A;  3T5G B;  5L7K A;  5E80 A;  1KSG B;  4GOJ C;  4JVF B;  5F2U A;  4JVB B;  4JV8 B;  3T5I A; 
#chains in the Genus database with same CATH topology
 3ZUD A;  3RBQ A;  4B5Q A;  5TB5 B;  4OY8 A;  2YOY A;  5FTZ A;  2LHS A;  5TAR B;  3T5G B;  3EJA A;  5L7K A;  1AJW A;  2JHZ A;  5IJU A;  3KYS A;  2YET A;  4OY6 A;  5ACF A;  4ALR A;  2VTC A;  5EMV A;  1FT3 A;  5DQE A;  4ALT A;  3JUA A;  4FMR A;  1HH4 D;  1KSH B;  2JHU A;  4GBO A;  2JHV A;  2JI0 A;  5E8F A;  4EIS A;  4ALS A;  2BEN A;  5E80 A;  1FT0 A;  1KSG B;  2R5O A;  4ALC A;  5F2U A;  4A02 A;  2BXW A;  4F38 B;  2BEM A;  4JV8 B;  4QI8 A;  3T5I A;  5EMW A;  1KSJ B;  4ALE A;  4RE1 A;  1RHO A;  4GOK C;  3GQQ A;  1DOA B;  4JHP B;  4EIS B;  5ACI A;  2JHT A;  2XWX A;  1QVY A;  1KMT A;  5AA7 A;  1FSO A;  2JHS A;  2YOW A;  4GOJ C;  3EII A;  4JVB B;  3UAM A;  3L15 A;  2JHY A;  5FJQ A;  5ACJ A;  1FST A;  4JV6 B;  4LN0 A;  4D7V A;  5DQ8 A;  2JHW A;  5HGU A;  4MAH A;  4EIR A;  5ACH A;  4D7U A;  4ALQ A;  5HNO A;  1GDF A;  4JVF B;  5ACG A;  5HNP A;  1DS6 B;  4MAI A;  5FOH A;  4OY7 A;  2YOX A;  2JHX A; 
#chains in the Genus database with same CATH homology
 1KSJ B;  1KSH B;  3RBQ A;  4JV6 B;  5TB5 B;  4GOK C;  3GQQ A;  4JHP B;  5TAR B;  5E8F A;  3T5G B;  5L7K A;  5E80 A;  1KSG B;  4GOJ C;  4JVF B;  5F2U A;  4JVB B;  4JV8 B;  3T5I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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