5HE0G

Bovine grk2 in complex with gbetagamma subunits and ccg215022
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
60
structure length
60
Chain Sequence
NTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Bos taurus
molecule keywords Beta-adrenergic receptor kinase 1
total genus 15
structure length 60
sequence length 60
ec nomenclature
pdb deposition date 2016-01-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
G PF00631 G-gamma GGL domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 5he0G00
1XHMB 3PVWG 2TRCG 3PVUG 2PBIA 1GOTG 4MK0G 1B9XB 1TBGE 5HE0G 5HE3G 1B9YB 5KDOG 3AH8G 1OMWG 4PNKG 3CIKG 3KRWG 3V5WG 5TDHG 3PSCG 5HE1G 1A0RG 5HE2G 4KFMG 3SN6G 1GP2G 3KRXG 1GG2G 2BCJG
chains in the Genus database with same CATH superfamily
1XHMB 3PVWG 2TRCG 3PVUG 2PBIA 1GOTG 4MK0G 1B9XB 1TBGE 5HE0G 5HE3G 1B9YB 5KDOG 1IOJA 3AH8G 1OMWG 1HFES 4PNKG 3CIKG 3KRWG 3V5WG 5TDHG 3PSCG 5HE1G 1A0RG 5HE2G 4KFMG 3SN6G 1GP2G 3KRXG 1GG2G 2BCJG
chains in the Genus database with same CATH topology
1XHMB 3PVWG 2TRCG 3PVUG 2PBIA 1GOTG 4MK0G 1B9XB 1TBGE 5HE0G 5HE3G 1B9YB 5KDOG 3AH8G 1OMWG 4PNKG 3CIKG 3KRWG 3V5WG 5TDHG 3PSCG 5HE1G 1A0RG 5HE2G 4KFMG 3SN6G 1GP2G 3KRXG 1GG2G 2BCJG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XHM B;  3PVW G;  2TRC G;  3PVU G;  2PBI A;  1GOT G;  4MK0 G;  1B9X B;  1TBG E;  5HE0 G;  5HE3 G;  1B9Y B;  5KDO G;  3AH8 G;  1OMW G;  4PNK G;  3CIK G;  3KRW G;  3V5W G;  5TDH G;  3PSC G;  5HE1 G;  1A0R G;  5HE2 G;  4KFM G;  3SN6 G;  1GP2 G;  3KRX G;  1GG2 G;  2BCJ G; 
#chains in the Genus database with same CATH topology
 1XHM B;  3PVW G;  2TRC G;  3PVU G;  2PBI A;  1GOT G;  4MK0 G;  1B9X B;  1TBG E;  5HE0 G;  5HE3 G;  1B9Y B;  5KDO G;  1IOJ A;  3AH8 G;  1OMW G;  1HFE S;  4PNK G;  3CIK G;  3KRW G;  3V5W G;  5TDH G;  3PSC G;  5HE1 G;  1A0R G;  5HE2 G;  4KFM G;  3SN6 G;  1GP2 G;  3KRX G;  1GG2 G;  2BCJ G; 
#chains in the Genus database with same CATH homology
 1XHM B;  3PVW G;  2TRC G;  3PVU G;  2PBI A;  1GOT G;  4MK0 G;  1B9X B;  1TBG E;  5HE0 G;  5HE3 G;  1B9Y B;  5KDO G;  3AH8 G;  1OMW G;  4PNK G;  3CIK G;  3KRW G;  3V5W G;  5TDH G;  3PSC G;  5HE1 G;  1A0R G;  5HE2 G;  4KFM G;  3SN6 G;  1GP2 G;  3KRX G;  1GG2 G;  2BCJ G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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