5HE2G

Bovine grk2 in complex with gbetagamma subunits and ccg224406
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
58
structure length
58
Chain Sequence
NTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors.
pubmed doi rcsb
molecule keywords Beta-adrenergic receptor kinase 1
molecule tags Transferase/transferase inhibitor
source organism Bos taurus
total genus 15
structure length 58
sequence length 58
ec nomenclature
pdb deposition date 2016-01-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
G PF00631 G-gamma GGL domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 5he2G00
3KRXG 5HE0G 5HE3G 5HE2G 1B9YB 4KFMG 3PSCG 3V5WG 1GG2G 3CIKG 3PVWG 5TDHG 2BCJG 1TBGE 1OMWG 3KRWG 4PNKG 1XHMB 1B9XB 1GOTG 3SN6G 2PBIA 2TRCG 5HE1G 4MK0G 5KDOG 3AH8G 1A0RG 3PVUG 1GP2G
chains in the Genus database with same CATH superfamily
3KRXG 5HE0G 5HE3G 5HE2G 1HFES 1B9YB 4KFMG 3PSCG 3V5WG 1GG2G 3CIKG 3PVWG 5TDHG 2BCJG 1TBGE 1OMWG 3KRWG 4PNKG 1XHMB 1B9XB 1GOTG 3SN6G 2PBIA 2TRCG 5HE1G 4MK0G 5KDOG 3AH8G 1A0RG 1IOJA 3PVUG 1GP2G
chains in the Genus database with same CATH topology
3KRXG 5HE0G 5HE3G 5HE2G 1B9YB 4KFMG 3PSCG 3V5WG 1GG2G 3CIKG 3PVWG 5TDHG 2BCJG 1TBGE 1OMWG 3KRWG 4PNKG 1XHMB 1B9XB 1GOTG 3SN6G 2PBIA 2TRCG 5HE1G 4MK0G 5KDOG 3AH8G 1A0RG 3PVUG 1GP2G
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KRX G;  5HE0 G;  5HE3 G;  5HE2 G;  1B9Y B;  4KFM G;  3PSC G;  3V5W G;  1GG2 G;  3CIK G;  3PVW G;  5TDH G;  2BCJ G;  1TBG E;  1OMW G;  3KRW G;  4PNK G;  1XHM B;  1B9X B;  1GOT G;  3SN6 G;  2PBI A;  2TRC G;  5HE1 G;  4MK0 G;  5KDO G;  3AH8 G;  1A0R G;  3PVU G;  1GP2 G; 
#chains in the Genus database with same CATH topology
 3KRX G;  5HE0 G;  5HE3 G;  5HE2 G;  1HFE S;  1B9Y B;  4KFM G;  3PSC G;  3V5W G;  1GG2 G;  3CIK G;  3PVW G;  5TDH G;  2BCJ G;  1TBG E;  1OMW G;  3KRW G;  4PNK G;  1XHM B;  1B9X B;  1GOT G;  3SN6 G;  2PBI A;  2TRC G;  5HE1 G;  4MK0 G;  5KDO G;  3AH8 G;  1A0R G;  1IOJ A;  3PVU G;  1GP2 G; 
#chains in the Genus database with same CATH homology
 3KRX G;  5HE0 G;  5HE3 G;  5HE2 G;  1B9Y B;  4KFM G;  3PSC G;  3V5W G;  1GG2 G;  3CIK G;  3PVW G;  5TDH G;  2BCJ G;  1TBG E;  1OMW G;  3KRW G;  4PNK G;  1XHM B;  1B9X B;  1GOT G;  3SN6 G;  2PBI A;  2TRC G;  5HE1 G;  4MK0 G;  5KDO G;  3AH8 G;  1A0R G;  3PVU G;  1GP2 G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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