5HE2G

Bovine grk2 in complex with gbetagamma subunits and ccg224406
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
58
structure length
58
Chain Sequence
NTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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connected with : NaN
publication title Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors.
pubmed doi rcsb
molecule keywords Beta-adrenergic receptor kinase 1
molecule tags Transferase/transferase inhibitor
source organism Bos taurus
total genus 15
structure length 58
sequence length 58
ec nomenclature
pdb deposition date 2016-01-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
G PF00631 G-gamma GGL domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 5he2G00
5TDHG 2TRCG 1GOTG 3AH8G 3PVWG 3KRXG 2PBIA 1A0RG 5HE1G 3PVUG 3KRWG 5HE3G 1GG2G 4KFMG 1TBGE 1B9YB 3V5WG 5HE0G 4MK0G 5HE2G 5KDOG 1XHMB 3CIKG 3SN6G 1OMWG 1GP2G 4PNKG 3PSCG 2BCJG 1B9XB
chains in the Genus database with same CATH superfamily
5TDHG 2TRCG 1GOTG 3AH8G 3PVWG 3KRXG 2PBIA 1A0RG 5HE1G 3PVUG 3KRWG 5HE3G 1GG2G 4KFMG 1TBGE 1B9YB 1HFES 3V5WG 5HE0G 4MK0G 5HE2G 5KDOG 1XHMB 3CIKG 3SN6G 1OMWG 1IOJA 1GP2G 4PNKG 3PSCG 2BCJG 1B9XB
chains in the Genus database with same CATH topology
5TDHG 2TRCG 1GOTG 3AH8G 3PVWG 3KRXG 2PBIA 1A0RG 5HE1G 3PVUG 3KRWG 5HE3G 1GG2G 4KFMG 1TBGE 1B9YB 3V5WG 5HE0G 4MK0G 5HE2G 5KDOG 1XHMB 3CIKG 3SN6G 1OMWG 1GP2G 4PNKG 3PSCG 2BCJG 1B9XB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5TDH G;  2TRC G;  1GOT G;  3AH8 G;  3PVW G;  3KRX G;  2PBI A;  1A0R G;  5HE1 G;  3PVU G;  3KRW G;  5HE3 G;  1GG2 G;  4KFM G;  1TBG E;  1B9Y B;  3V5W G;  5HE0 G;  4MK0 G;  5HE2 G;  5KDO G;  1XHM B;  3CIK G;  3SN6 G;  1OMW G;  1GP2 G;  4PNK G;  3PSC G;  2BCJ G;  1B9X B; 
#chains in the Genus database with same CATH topology
 5TDH G;  2TRC G;  1GOT G;  3AH8 G;  3PVW G;  3KRX G;  2PBI A;  1A0R G;  5HE1 G;  3PVU G;  3KRW G;  5HE3 G;  1GG2 G;  4KFM G;  1TBG E;  1B9Y B;  1HFE S;  3V5W G;  5HE0 G;  4MK0 G;  5HE2 G;  5KDO G;  1XHM B;  3CIK G;  3SN6 G;  1OMW G;  1IOJ A;  1GP2 G;  4PNK G;  3PSC G;  2BCJ G;  1B9X B; 
#chains in the Genus database with same CATH homology
 5TDH G;  2TRC G;  1GOT G;  3AH8 G;  3PVW G;  3KRX G;  2PBI A;  1A0R G;  5HE1 G;  3PVU G;  3KRW G;  5HE3 G;  1GG2 G;  4KFM G;  1TBG E;  1B9Y B;  3V5W G;  5HE0 G;  4MK0 G;  5HE2 G;  5KDO G;  1XHM B;  3CIK G;  3SN6 G;  1OMW G;  1GP2 G;  4PNK G;  3PSC G;  2BCJ G;  1B9X B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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