5HE3G

Bovine grk2 in complex with gbetagamma subunits and ccg224411
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
58
structure length
58
Chain Sequence
TASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFRE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Bos taurus
molecule keywords Beta-adrenergic receptor kinase 1
total genus 14
structure length 58
sequence length 58
ec nomenclature
pdb deposition date 2016-01-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
G PF00631 G-gamma GGL domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 5he3G00
1GP2G 4MK0G 3KRXG 3AH8G 4KFMG 5KDOG 3PVWG 3KRWG 2TRCG 1XHMB 1A0RG 2PBIA 1GG2G 5HE2G 3PVUG 4PNKG 1B9YB 5HE0G 1GOTG 5HE3G 5TDHG 3CIKG 3PSCG 1OMWG 3SN6G 3V5WG 5HE1G 1TBGE 2BCJG 1B9XB
chains in the Genus database with same CATH superfamily
1GP2G 4MK0G 1HFES 3KRXG 3AH8G 4KFMG 5KDOG 1IOJA 3PVWG 3KRWG 2TRCG 1XHMB 1A0RG 2PBIA 1GG2G 5HE2G 3PVUG 4PNKG 1B9YB 5HE0G 1GOTG 5HE3G 5TDHG 3CIKG 3PSCG 1OMWG 3SN6G 3V5WG 5HE1G 1TBGE 2BCJG 1B9XB
chains in the Genus database with same CATH topology
1GP2G 4MK0G 3KRXG 3AH8G 4KFMG 5KDOG 3PVWG 3KRWG 2TRCG 1XHMB 1A0RG 2PBIA 1GG2G 5HE2G 3PVUG 4PNKG 1B9YB 5HE0G 1GOTG 5HE3G 5TDHG 3CIKG 3PSCG 1OMWG 3SN6G 3V5WG 5HE1G 1TBGE 2BCJG 1B9XB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GP2 G;  4MK0 G;  3KRX G;  3AH8 G;  4KFM G;  5KDO G;  3PVW G;  3KRW G;  2TRC G;  1XHM B;  1A0R G;  2PBI A;  1GG2 G;  5HE2 G;  3PVU G;  4PNK G;  1B9Y B;  5HE0 G;  1GOT G;  5HE3 G;  5TDH G;  3CIK G;  3PSC G;  1OMW G;  3SN6 G;  3V5W G;  5HE1 G;  1TBG E;  2BCJ G;  1B9X B; 
#chains in the Genus database with same CATH topology
 1GP2 G;  4MK0 G;  1HFE S;  3KRX G;  3AH8 G;  4KFM G;  5KDO G;  1IOJ A;  3PVW G;  3KRW G;  2TRC G;  1XHM B;  1A0R G;  2PBI A;  1GG2 G;  5HE2 G;  3PVU G;  4PNK G;  1B9Y B;  5HE0 G;  1GOT G;  5HE3 G;  5TDH G;  3CIK G;  3PSC G;  1OMW G;  3SN6 G;  3V5W G;  5HE1 G;  1TBG E;  2BCJ G;  1B9X B; 
#chains in the Genus database with same CATH homology
 1GP2 G;  4MK0 G;  3KRX G;  3AH8 G;  4KFM G;  5KDO G;  3PVW G;  3KRW G;  2TRC G;  1XHM B;  1A0R G;  2PBI A;  1GG2 G;  5HE2 G;  3PVU G;  4PNK G;  1B9Y B;  5HE0 G;  1GOT G;  5HE3 G;  5TDH G;  3CIK G;  3PSC G;  1OMW G;  3SN6 G;  3V5W G;  5HE1 G;  1TBG E;  2BCJ G;  1B9X B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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