5I4ZA

Structure of apo omomyc
Total Genus 30
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
74
structure length
74
Chain Sequence
RRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAETQKLISEIDLLRKQNEQLKHKLEQLRNSCA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors.
pubmed doi rcsb
molecule keywords Myc proto-oncogene protein
molecule tags Transcription
source organism Homo sapiens
total genus 30
structure length 74
sequence length 74
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-02-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00010 HLH Helix-loop-helix DNA-binding domain
A PF02344 Myc-LZ Myc leucine zipper domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 5i4zA00
5I4ZA 1AM9A 1MDYB 5EYOA 2YPBA 1AN2A 4ATKA 2YPAB 4AYAA 2QL2A 4ATIA 4H10A 1NKPA 1A0AA 2LFHA 2YPBB 4F3LA 1NLWA 3MUJA 2QL2B 1NKPB 4H10B 1AN4A 2MH3A 3U5VA 4F3LB 1UKLC 4ATHA 1MDYA 1NLWB 1HLOA 5I50A 2YPAA 1R05A
chains in the Genus database with same CATH superfamily
5I4ZA 1AM9A 1MDYB 5EYOA 2YPBA 1AN2A 4ATKA 2YPAB 4AYAA 2QL2A 4ATIA 4H10A 1NKPA 1A0AA 2LFHA 2YPBB 4F3LA 1NLWA 3MUJA 2QL2B 1NKPB 4H10B 1AN4A 2MH3A 3U5VA 4F3LB 1K1FA 1UKLC 4ATHA 1MDYA 1NLWB 1HLOA 5I50A 2YPAA 1R05A 1ZZAA
chains in the Genus database with same CATH topology
5I4ZA 1AM9A 1MDYB 5EYOA 2YPBA 1AN2A 4ATKA 2YPAB 4AYAA 2QL2A 4ATIA 4H10A 1NKPA 1A0AA 2LFHA 2YPBB 4F3LA 1NLWA 3MUJA 2QL2B 1NKPB 4H10B 1AN4A 2MH3A 3U5VA 4F3LB 1UKLC 4ATHA 1MDYA 1NLWB 1HLOA 5I50A 2YPAA 1R05A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5I4Z A;  1AM9 A;  1MDY B;  5EYO A;  2YPB A;  1AN2 A;  4ATK A;  2YPA B;  4AYA A;  2QL2 A;  4ATI A;  4H10 A;  1NKP A;  1A0A A;  2LFH A;  2YPB B;  4F3L A;  1NLW A;  3MUJ A;  2QL2 B;  1NKP B;  4H10 B;  1AN4 A;  2MH3 A;  3U5V A;  4F3L B;  1UKL C;  4ATH A;  1MDY A;  1NLW B;  1HLO A;  5I50 A;  2YPA A;  1R05 A; 
#chains in the Genus database with same CATH topology
 5I4Z A;  1AM9 A;  1MDY B;  5EYO A;  2YPB A;  1AN2 A;  4ATK A;  2YPA B;  4AYA A;  2QL2 A;  4ATI A;  4H10 A;  1NKP A;  1A0A A;  2LFH A;  2YPB B;  4F3L A;  1NLW A;  3MUJ A;  2QL2 B;  1NKP B;  4H10 B;  1AN4 A;  2MH3 A;  3U5V A;  4F3L B;  1K1F A;  1UKL C;  4ATH A;  1MDY A;  1NLW B;  1HLO A;  5I50 A;  2YPA A;  1R05 A;  1ZZA A; 
#chains in the Genus database with same CATH homology
 5I4Z A;  1AM9 A;  1MDY B;  5EYO A;  2YPB A;  1AN2 A;  4ATK A;  2YPA B;  4AYA A;  2QL2 A;  4ATI A;  4H10 A;  1NKP A;  1A0A A;  2LFH A;  2YPB B;  4F3L A;  1NLW A;  3MUJ A;  2QL2 B;  1NKP B;  4H10 B;  1AN4 A;  2MH3 A;  3U5V A;  4F3L B;  1UKL C;  4ATH A;  1MDY A;  1NLW B;  1HLO A;  5I50 A;  2YPA A;  1R05 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...