5I4ZA

Structure of apo omomyc
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
74
structure length
74
Chain Sequence
RRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAETQKLISEIDLLRKQNEQLKHKLEQLRNSCA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors.
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords Myc proto-oncogene protein
total genus 30
structure length 74
sequence length 74
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-02-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00010 HLH Helix-loop-helix DNA-binding domain
A PF02344 Myc-LZ Myc leucine zipper domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 5i4zA00
3U5VA 4H10B 1NLWA 3MUJA 4AYAA 4F3LB 2YPBA 1AN4A 1AN2A 2MH3A 2QL2B 1NKPA 2YPAB 1HLOA 5EYOA 1MDYA 5I4ZA 4H10A 1NLWB 1UKLC 2YPBB 2LFHA 5I50A 4ATHA 4F3LA 1AM9A 1NKPB 2QL2A 4ATKA 4ATIA 1A0AA 1R05A 2YPAA 1MDYB
chains in the Genus database with same CATH superfamily
3U5VA 4H10B 1NLWA 3MUJA 4AYAA 4F3LB 2YPBA 1AN4A 1AN2A 2MH3A 2QL2B 1NKPA 2YPAB 1HLOA 5EYOA 1ZZAA 1MDYA 5I4ZA 4H10A 1NLWB 1UKLC 2YPBB 2LFHA 5I50A 4ATHA 4F3LA 1AM9A 1NKPB 2QL2A 4ATKA 4ATIA 1A0AA 1K1FA 1R05A 2YPAA 1MDYB
chains in the Genus database with same CATH topology
3U5VA 4H10B 1NLWA 3MUJA 4AYAA 4F3LB 2YPBA 1AN4A 1AN2A 2MH3A 2QL2B 1NKPA 2YPAB 1HLOA 5EYOA 1MDYA 5I4ZA 4H10A 1NLWB 1UKLC 2YPBB 2LFHA 5I50A 4ATHA 4F3LA 1AM9A 1NKPB 2QL2A 4ATKA 4ATIA 1A0AA 1R05A 2YPAA 1MDYB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3U5V A;  4H10 B;  1NLW A;  3MUJ A;  4AYA A;  4F3L B;  2YPB A;  1AN4 A;  1AN2 A;  2MH3 A;  2QL2 B;  1NKP A;  2YPA B;  1HLO A;  5EYO A;  1MDY A;  5I4Z A;  4H10 A;  1NLW B;  1UKL C;  2YPB B;  2LFH A;  5I50 A;  4ATH A;  4F3L A;  1AM9 A;  1NKP B;  2QL2 A;  4ATK A;  4ATI A;  1A0A A;  1R05 A;  2YPA A;  1MDY B; 
#chains in the Genus database with same CATH topology
 3U5V A;  4H10 B;  1NLW A;  3MUJ A;  4AYA A;  4F3L B;  2YPB A;  1AN4 A;  1AN2 A;  2MH3 A;  2QL2 B;  1NKP A;  2YPA B;  1HLO A;  5EYO A;  1ZZA A;  1MDY A;  5I4Z A;  4H10 A;  1NLW B;  1UKL C;  2YPB B;  2LFH A;  5I50 A;  4ATH A;  4F3L A;  1AM9 A;  1NKP B;  2QL2 A;  4ATK A;  4ATI A;  1A0A A;  1K1F A;  1R05 A;  2YPA A;  1MDY B; 
#chains in the Genus database with same CATH homology
 3U5V A;  4H10 B;  1NLW A;  3MUJ A;  4AYA A;  4F3L B;  2YPB A;  1AN4 A;  1AN2 A;  2MH3 A;  2QL2 B;  1NKP A;  2YPA B;  1HLO A;  5EYO A;  1MDY A;  5I4Z A;  4H10 A;  1NLW B;  1UKL C;  2YPB B;  2LFH A;  5I50 A;  4ATH A;  4F3L A;  1AM9 A;  1NKP B;  2QL2 A;  4ATK A;  4ATI A;  1A0A A;  1R05 A;  2YPA A;  1MDY B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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