5I50A

Structure of omomyc bound to double-stranded dna
Total Genus 41
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
92
structure length
92
Chain Sequence
MATEENVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAETQKLISEIDLLRKQNEQLKHKLEQLRNSCA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors.
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords Myc proto-oncogene protein
total genus 41
structure length 92
sequence length 92
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-02-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00010 HLH Helix-loop-helix DNA-binding domain
A PF02344 Myc-LZ Myc leucine zipper domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 5i50A00
4F3LA 2YPAA 4ATKA 4H10A 1NKPB 1HLOA 1MDYA 2YPBA 1NLWA 1AN2A 2LFHA 1UKLC 1AN4A 4AYAA 1A0AA 2QL2B 1AM9A 1NKPA 5I50A 2YPAB 4F3LB 4ATHA 4H10B 1R05A 5I4ZA 5EYOA 2MH3A 4ATIA 1NLWB 1MDYB 2YPBB 3MUJA 3U5VA 2QL2A
chains in the Genus database with same CATH superfamily
4F3LA 2YPAA 4ATKA 1ZZAA 4H10A 1NKPB 1HLOA 1K1FA 1MDYA 2YPBA 1NLWA 1AN2A 2LFHA 1UKLC 1AN4A 4AYAA 1A0AA 2QL2B 1AM9A 1NKPA 5I50A 2YPAB 4F3LB 4ATHA 4H10B 1R05A 5I4ZA 5EYOA 2MH3A 4ATIA 1NLWB 1MDYB 2YPBB 3MUJA 3U5VA 2QL2A
chains in the Genus database with same CATH topology
4F3LA 2YPAA 4ATKA 4H10A 1NKPB 1HLOA 1MDYA 2YPBA 1NLWA 1AN2A 2LFHA 1UKLC 1AN4A 4AYAA 1A0AA 2QL2B 1AM9A 1NKPA 5I50A 2YPAB 4F3LB 4ATHA 4H10B 1R05A 5I4ZA 5EYOA 2MH3A 4ATIA 1NLWB 1MDYB 2YPBB 3MUJA 3U5VA 2QL2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4F3L A;  2YPA A;  4ATK A;  4H10 A;  1NKP B;  1HLO A;  1MDY A;  2YPB A;  1NLW A;  1AN2 A;  2LFH A;  1UKL C;  1AN4 A;  4AYA A;  1A0A A;  2QL2 B;  1AM9 A;  1NKP A;  5I50 A;  2YPA B;  4F3L B;  4ATH A;  4H10 B;  1R05 A;  5I4Z A;  5EYO A;  2MH3 A;  4ATI A;  1NLW B;  1MDY B;  2YPB B;  3MUJ A;  3U5V A;  2QL2 A; 
#chains in the Genus database with same CATH topology
 4F3L A;  2YPA A;  4ATK A;  1ZZA A;  4H10 A;  1NKP B;  1HLO A;  1K1F A;  1MDY A;  2YPB A;  1NLW A;  1AN2 A;  2LFH A;  1UKL C;  1AN4 A;  4AYA A;  1A0A A;  2QL2 B;  1AM9 A;  1NKP A;  5I50 A;  2YPA B;  4F3L B;  4ATH A;  4H10 B;  1R05 A;  5I4Z A;  5EYO A;  2MH3 A;  4ATI A;  1NLW B;  1MDY B;  2YPB B;  3MUJ A;  3U5V A;  2QL2 A; 
#chains in the Genus database with same CATH homology
 4F3L A;  2YPA A;  4ATK A;  4H10 A;  1NKP B;  1HLO A;  1MDY A;  2YPB A;  1NLW A;  1AN2 A;  2LFH A;  1UKL C;  1AN4 A;  4AYA A;  1A0A A;  2QL2 B;  1AM9 A;  1NKP A;  5I50 A;  2YPA B;  4F3L B;  4ATH A;  4H10 B;  1R05 A;  5I4Z A;  5EYO A;  2MH3 A;  4ATI A;  1NLW B;  1MDY B;  2YPB B;  3MUJ A;  3U5V A;  2QL2 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...