5II0A

Crystal structure of the human calcitonin receptor ectodomain in complex with a truncated salmon calcitonin analogue
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
99
structure length
99
Chain Sequence
LYVVGRKKMMDAQYKCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFKHPENNRTWSNYTMCNAFT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Type II Turn of Receptor-bound Salmon Calcitonin Revealed by X-ray Crystallography.
pubmed doi rcsb
molecule tags Hormone
source organism Homo sapiens
molecule keywords Calcitonin receptor
total genus 22
structure length 99
sequence length 99
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2016-03-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02793 HRM Hormone receptor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.1240.10 Few Secondary Structures Irregular Hormone receptor fold GPCR, family 2, extracellular hormone receptor domain 5ii0A00
4ZGMA 3EHTA 2L27A 4LF3C 1U34A 3N7SA 4HJ0A 4DLOA 3C4MA 4ERSA 5II0A 3EHUA 3L2JA 3IOLA 2QKHA 2JODA 2JNCA 3EHSA 3C5TA 3AQFB 2JNDA 3H3GA 3N7PA 3C59A 2XDGA 3N7RA 4DLQA
chains in the Genus database with same CATH superfamily
4ZGMA 3EHTA 2L27A 4LF3C 1U34A 3N7SA 4HJ0A 4DLOA 3C4MA 4ERSA 5II0A 3EHUA 3L2JA 3IOLA 2QKHA 2JODA 2JNCA 3EHSA 3C5TA 3AQFB 2JNDA 3H3GA 3N7PA 3C59A 2XDGA 3N7RA 4DLQA
chains in the Genus database with same CATH topology
4ZGMA 3EHTA 2L27A 4LF3C 1U34A 3N7SA 4HJ0A 4DLOA 3C4MA 4ERSA 5II0A 3EHUA 3L2JA 3IOLA 2QKHA 2JODA 2JNCA 3EHSA 3C5TA 3AQFB 2JNDA 3H3GA 3N7PA 3C59A 2XDGA 3N7RA 4DLQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZGM A;  3EHT A;  2L27 A;  4LF3 C;  1U34 A;  3N7S A;  4HJ0 A;  4DLO A;  3C4M A;  4ERS A;  5II0 A;  3EHU A;  3L2J A;  3IOL A;  2QKH A;  2JOD A;  2JNC A;  3EHS A;  3C5T A;  3AQF B;  2JND A;  3H3G A;  3N7P A;  3C59 A;  2XDG A;  3N7R A;  4DLQ A; 
#chains in the Genus database with same CATH topology
 4ZGM A;  3EHT A;  2L27 A;  4LF3 C;  1U34 A;  3N7S A;  4HJ0 A;  4DLO A;  3C4M A;  4ERS A;  5II0 A;  3EHU A;  3L2J A;  3IOL A;  2QKH A;  2JOD A;  2JNC A;  3EHS A;  3C5T A;  3AQF B;  2JND A;  3H3G A;  3N7P A;  3C59 A;  2XDG A;  3N7R A;  4DLQ A; 
#chains in the Genus database with same CATH homology
 4ZGM A;  3EHT A;  2L27 A;  4LF3 C;  1U34 A;  3N7S A;  4HJ0 A;  4DLO A;  3C4M A;  4ERS A;  5II0 A;  3EHU A;  3L2J A;  3IOL A;  2QKH A;  2JOD A;  2JNC A;  3EHS A;  3C5T A;  3AQF B;  2JND A;  3H3G A;  3N7P A;  3C59 A;  2XDG A;  3N7R A;  4DLQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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