5J6CA

Fmn-dependent nitroreductase (cdr20291_0767) from clostridium difficile r20291
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
173
structure length
173
Chain Sequence
MIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSKGLRTWEFIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAASYIQLQAHELGLGSCWIQVRNRMYDDNIEADKYIREELKVPSKYSVECIISIGYSDEEKKAYNDSDLDYKKVHFNNF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of two nitroreductases from hypervirulent Clostridium difficile and functionally related interactions with the antibiotic metronidazole.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Peptoclostridium difficile (strain r20291)
molecule keywords Putative reductase
total genus 50
structure length 173
sequence length 173
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-04-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00881 Nitroreductase Nitroreductase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.109.10 Alpha Beta 3-Layer(aba) Sandwich NADH Oxidase NADH Oxidase 5j6cA00
3TNZA 4G8SA 3K6HA 2HAYA 3OF4A 4BNBA 1ICRA 2WZWA 1OO6A 3GB5A 3GE6A 1ICVA 3BM1A 1VFRA 2ISKA 4DN2A 3N2SA 3GE5A 3GFDA 3BM2A 2ISJA 1YWQA 3X22A 2YMVA 3KOQA 1KQCA 3GBHA 3EOFA 4XOOA 2BKJA 5HDJA 3H4OA 3EK3A 4XOQA 2R01A 2WQFA 4BN6A 3G14A 5HEIA 2I7HA 1VKWA 3E39A 4XOMA 2ISLA 1ZCHA 3E10A 3M5KA 1NOXA 1ICUA 3QDLA 4BN7A 1IDTA 4TTBA 1BKJA 5KO8A 1KQBA 1YKIA 3GH8A 1V5ZA 1YLUA 4QLXA 4URPA 3EO7A 3HJ9A 1KQDA 1DS7A 1F5VA 2H0UA 1OOQA 3TO0A 5KO7A 3EO8A 3KWKA 5KRDA 4BN9A 3GAGA 3PXVA 4TTCA 3HZNA 3HOIA 4QLYA 2B67A 2FREA 2WZVA 4EO3A 3BEMA 2IFAA 1YLRA 1NECA 4BN8A 5J6CA 1OO5A 1OONA 3GFAA 3X21A 3GR3A 1V5YA
chains in the Genus database with same CATH superfamily
3TNZA 4G8SA 3K6HA 2HAYA 3OF4A 4BNBA 1ICRA 2WZWA 1OO6A 3GB5A 3GE6A 1ICVA 3BM1A 1VFRA 2ISKA 4DN2A 3N2SA 3GE5A 3GFDA 3BM2A 2ISJA 1YWQA 3X22A 2YMVA 3KOQA 1KQCA 3GBHA 3EOFA 4XOOA 2BKJA 5HDJA 3H4OA 3EK3A 4XOQA 2R01A 2WQFA 4BN6A 3G14A 5HEIA 1J6RA 2I7HA 1VKWA 3E39A 4XOMA 2ISLA 1ZCHA 3E10A 3M5KA 1NOXA 1ICUA 3QDLA 4BN7A 1IDTA 4TTBA 1BKJA 5KO8A 1KQBA 1YKIA 3GH8A 1V5ZA 1YLUA 4QLXA 4URPA 3EO7A 3HJ9A 1KQDA 1DS7A 1F5VA 2H0UA 1OOQA 3TO0A 5KO7A 3EO8A 3KWKA 5KRDA 4BN9A 3GAGA 3PXVA 4TTCA 3HZNA 3HOIA 4QLYA 2B67A 2FREA 2WZVA 4EO3A 3BEMA 2IFAA 1YLRA 1NECA 4BN8A 5J6CA 1OO5A 1OONA 3GFAA 3X21A 3GR3A 1V5YA
chains in the Genus database with same CATH topology
3TNZA 4G8SA 3K6HA 2HAYA 3OF4A 4BNBA 1ICRA 2WZWA 1OO6A 3GB5A 3GE6A 1ICVA 3BM1A 1VFRA 2ISKA 4DN2A 3N2SA 3GE5A 3GFDA 3BM2A 2ISJA 1YWQA 3X22A 2YMVA 3KOQA 1KQCA 3GBHA 3EOFA 4XOOA 2BKJA 5HDJA 3H4OA 3EK3A 4XOQA 2R01A 2WQFA 4BN6A 3G14A 5HEIA 1J6RA 2I7HA 1VKWA 3E39A 4XOMA 2ISLA 1ZCHA 3E10A 3M5KA 1NOXA 1ICUA 3QDLA 4BN7A 1IDTA 4TTBA 1BKJA 5KO8A 1KQBA 1YKIA 3GH8A 1V5ZA 1YLUA 4QLXA 4URPA 3EO7A 3HJ9A 1KQDA 1DS7A 1F5VA 2H0UA 1OOQA 3TO0A 5KO7A 3EO8A 3KWKA 5KRDA 4BN9A 3GAGA 3PXVA 4TTCA 3HZNA 3HOIA 4QLYA 2B67A 2FREA 2WZVA 4EO3A 3BEMA 2IFAA 1YLRA 1NECA 4BN8A 5J6CA 1OO5A 1OONA 3GFAA 3X21A 3GR3A 1V5YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TNZ A;  4G8S A;  3K6H A;  2HAY A;  3OF4 A;  4BNB A;  1ICR A;  2WZW A;  1OO6 A;  3GB5 A;  3GE6 A;  1ICV A;  3BM1 A;  1VFR A;  2ISK A;  4DN2 A;  3N2S A;  3GE5 A;  3GFD A;  3BM2 A;  2ISJ A;  1YWQ A;  3X22 A;  2YMV A;  3KOQ A;  1KQC A;  3GBH A;  3EOF A;  4XOO A;  2BKJ A;  5HDJ A;  3H4O A;  3EK3 A;  4XOQ A;  2R01 A;  2WQF A;  4BN6 A;  3G14 A;  5HEI A;  2I7H A;  1VKW A;  3E39 A;  4XOM A;  2ISL A;  1ZCH A;  3E10 A;  3M5K A;  1NOX A;  1ICU A;  3QDL A;  4BN7 A;  1IDT A;  4TTB A;  1BKJ A;  5KO8 A;  1KQB A;  1YKI A;  3GH8 A;  1V5Z A;  1YLU A;  4QLX A;  4URP A;  3EO7 A;  3HJ9 A;  1KQD A;  1DS7 A;  1F5V A;  2H0U A;  1OOQ A;  3TO0 A;  5KO7 A;  3EO8 A;  3KWK A;  5KRD A;  4BN9 A;  3GAG A;  3PXV A;  4TTC A;  3HZN A;  3HOI A;  4QLY A;  2B67 A;  2FRE A;  2WZV A;  4EO3 A;  3BEM A;  2IFA A;  1YLR A;  1NEC A;  4BN8 A;  5J6C A;  1OO5 A;  1OON A;  3GFA A;  3X21 A;  3GR3 A;  1V5Y A; 
#chains in the Genus database with same CATH topology
 3TNZ A;  4G8S A;  3K6H A;  2HAY A;  3OF4 A;  4BNB A;  1ICR A;  2WZW A;  1OO6 A;  3GB5 A;  3GE6 A;  1ICV A;  3BM1 A;  1VFR A;  2ISK A;  4DN2 A;  3N2S A;  3GE5 A;  3GFD A;  3BM2 A;  2ISJ A;  1YWQ A;  3X22 A;  2YMV A;  3KOQ A;  1KQC A;  3GBH A;  3EOF A;  4XOO A;  2BKJ A;  5HDJ A;  3H4O A;  3EK3 A;  4XOQ A;  2R01 A;  2WQF A;  4BN6 A;  3G14 A;  5HEI A;  1J6R A;  2I7H A;  1VKW A;  3E39 A;  4XOM A;  2ISL A;  1ZCH A;  3E10 A;  3M5K A;  1NOX A;  1ICU A;  3QDL A;  4BN7 A;  1IDT A;  4TTB A;  1BKJ A;  5KO8 A;  1KQB A;  1YKI A;  3GH8 A;  1V5Z A;  1YLU A;  4QLX A;  4URP A;  3EO7 A;  3HJ9 A;  1KQD A;  1DS7 A;  1F5V A;  2H0U A;  1OOQ A;  3TO0 A;  5KO7 A;  3EO8 A;  3KWK A;  5KRD A;  4BN9 A;  3GAG A;  3PXV A;  4TTC A;  3HZN A;  3HOI A;  4QLY A;  2B67 A;  2FRE A;  2WZV A;  4EO3 A;  3BEM A;  2IFA A;  1YLR A;  1NEC A;  4BN8 A;  5J6C A;  1OO5 A;  1OON A;  3GFA A;  3X21 A;  3GR3 A;  1V5Y A; 
#chains in the Genus database with same CATH homology
 3TNZ A;  4G8S A;  3K6H A;  2HAY A;  3OF4 A;  4BNB A;  1ICR A;  2WZW A;  1OO6 A;  3GB5 A;  3GE6 A;  1ICV A;  3BM1 A;  1VFR A;  2ISK A;  4DN2 A;  3N2S A;  3GE5 A;  3GFD A;  3BM2 A;  2ISJ A;  1YWQ A;  3X22 A;  2YMV A;  3KOQ A;  1KQC A;  3GBH A;  3EOF A;  4XOO A;  2BKJ A;  5HDJ A;  3H4O A;  3EK3 A;  4XOQ A;  2R01 A;  2WQF A;  4BN6 A;  3G14 A;  5HEI A;  1J6R A;  2I7H A;  1VKW A;  3E39 A;  4XOM A;  2ISL A;  1ZCH A;  3E10 A;  3M5K A;  1NOX A;  1ICU A;  3QDL A;  4BN7 A;  1IDT A;  4TTB A;  1BKJ A;  5KO8 A;  1KQB A;  1YKI A;  3GH8 A;  1V5Z A;  1YLU A;  4QLX A;  4URP A;  3EO7 A;  3HJ9 A;  1KQD A;  1DS7 A;  1F5V A;  2H0U A;  1OOQ A;  3TO0 A;  5KO7 A;  3EO8 A;  3KWK A;  5KRD A;  4BN9 A;  3GAG A;  3PXV A;  4TTC A;  3HZN A;  3HOI A;  4QLY A;  2B67 A;  2FRE A;  2WZV A;  4EO3 A;  3BEM A;  2IFA A;  1YLR A;  1NEC A;  4BN8 A;  5J6C A;  1OO5 A;  1OON A;  3GFA A;  3X21 A;  3GR3 A;  1V5Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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