5KO8A

Crystal structure of haliscomenobacter hydrossis iodotyrosine deiodinase (iyd) bound to fmn and mono-iodotyrosine (i-tyr)
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
218
structure length
215
Chain Sequence
AFIPYAGAQFEPEEMLSKSAEYYQFMDHRRTVREFSNRAIPLEVIENIVMTASTAPSGAHKQPWTFVVVSDPQIKAKIRQAAEKEEFESYNGNEWLEDLQPFGTDWHKPFLEIAPYLIVVFRKAYDVLPDGTQRKNYYVQESVGIACGFLLAAIHQAGLVALTHTPSPMNFLQKILQRPENERPFLLVPVGYPAEGAMVPDLQRKDKAAVMVVYH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine Deiodinase.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Haliscomenobacter hydrossis (strain atcc 27775 / dsm 1100 / lmg 10767 / o)
molecule keywords Nitroreductase
total genus 51
structure length 215
sequence length 218
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00881 Nitroreductase Nitroreductase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.109.10 Alpha Beta 3-Layer(aba) Sandwich NADH Oxidase NADH Oxidase 5ko8A00
3QDLA 5HDJA 1VFRA 3HZNA 1BKJA 2ISLA 1OO6A 4XOMA 3BEMA 2FREA 3TO0A 3GR3A 3GE6A 1KQCA 4EO3A 3M5KA 5KRDA 1OO5A 3EO8A 1YLUA 3X22A 4BN8A 3OF4A 3GE5A 4BN7A 2H0UA 3HJ9A 3BM1A 3EOFA 4TTBA 1ICVA 1YWQA 1ZCHA 1V5YA 3EK3A 4BN6A 1F5VA 1OONA 2B67A 4BNBA 3GFAA 5KO8A 1KQDA 1NECA 3BM2A 4XOOA 4BN9A 1OOQA 4URPA 2IFAA 4TTCA 3GH8A 3HOIA 2R01A 2ISKA 3GBHA 3PXVA 3GFDA 5J6CA 3N2SA 2YMVA 3EO7A 4XOQA 2I7HA 2HAYA 4G8SA 2WZVA 4DN2A 2WQFA 2ISJA 3E39A 2WZWA 1DS7A 3GB5A 1ICRA 1NOXA 3G14A 5HEIA 1VKWA 3K6HA 1YKIA 3KOQA 3H4OA 1YLRA 3GAGA 1IDTA 5KO7A 4QLYA 1ICUA 1KQBA 3X21A 1V5ZA 3TNZA 4QLXA 2BKJA 3KWKA 3E10A
chains in the Genus database with same CATH superfamily
3QDLA 5HDJA 1VFRA 3HZNA 1BKJA 2ISLA 1OO6A 4XOMA 3BEMA 2FREA 3TO0A 3GR3A 3GE6A 1KQCA 4EO3A 3M5KA 5KRDA 1OO5A 3EO8A 1YLUA 3X22A 4BN8A 3OF4A 3GE5A 4BN7A 2H0UA 3HJ9A 3BM1A 3EOFA 4TTBA 1ICVA 1YWQA 1ZCHA 1V5YA 3EK3A 4BN6A 1F5VA 1OONA 2B67A 4BNBA 3GFAA 5KO8A 1KQDA 1NECA 3BM2A 4XOOA 4BN9A 1OOQA 4URPA 2IFAA 4TTCA 3GH8A 3HOIA 2R01A 2ISKA 3GBHA 3PXVA 3GFDA 5J6CA 1J6RA 3N2SA 2YMVA 3EO7A 4XOQA 2I7HA 2HAYA 4G8SA 2WZVA 4DN2A 2WQFA 2ISJA 3E39A 2WZWA 1DS7A 3GB5A 1ICRA 1NOXA 3G14A 5HEIA 1VKWA 3K6HA 1YKIA 3KOQA 3H4OA 1YLRA 3GAGA 1IDTA 5KO7A 4QLYA 1ICUA 1KQBA 3X21A 1V5ZA 3TNZA 4QLXA 2BKJA 3KWKA 3E10A
chains in the Genus database with same CATH topology
3QDLA 5HDJA 1VFRA 3HZNA 1BKJA 2ISLA 1OO6A 4XOMA 3BEMA 2FREA 3TO0A 3GR3A 3GE6A 1KQCA 4EO3A 3M5KA 5KRDA 1OO5A 3EO8A 1YLUA 3X22A 4BN8A 3OF4A 3GE5A 4BN7A 2H0UA 3HJ9A 3BM1A 3EOFA 4TTBA 1ICVA 1YWQA 1ZCHA 1V5YA 3EK3A 4BN6A 1F5VA 1OONA 2B67A 4BNBA 3GFAA 5KO8A 1KQDA 1NECA 3BM2A 4XOOA 4BN9A 1OOQA 4URPA 2IFAA 4TTCA 3GH8A 3HOIA 2R01A 2ISKA 3GBHA 3PXVA 3GFDA 5J6CA 1J6RA 3N2SA 2YMVA 3EO7A 4XOQA 2I7HA 2HAYA 4G8SA 2WZVA 4DN2A 2WQFA 2ISJA 3E39A 2WZWA 1DS7A 3GB5A 1ICRA 1NOXA 3G14A 5HEIA 1VKWA 3K6HA 1YKIA 3KOQA 3H4OA 1YLRA 3GAGA 1IDTA 5KO7A 4QLYA 1ICUA 1KQBA 3X21A 1V5ZA 3TNZA 4QLXA 2BKJA 3KWKA 3E10A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QDL A;  5HDJ A;  1VFR A;  3HZN A;  1BKJ A;  2ISL A;  1OO6 A;  4XOM A;  3BEM A;  2FRE A;  3TO0 A;  3GR3 A;  3GE6 A;  1KQC A;  4EO3 A;  3M5K A;  5KRD A;  1OO5 A;  3EO8 A;  1YLU A;  3X22 A;  4BN8 A;  3OF4 A;  3GE5 A;  4BN7 A;  2H0U A;  3HJ9 A;  3BM1 A;  3EOF A;  4TTB A;  1ICV A;  1YWQ A;  1ZCH A;  1V5Y A;  3EK3 A;  4BN6 A;  1F5V A;  1OON A;  2B67 A;  4BNB A;  3GFA A;  5KO8 A;  1KQD A;  1NEC A;  3BM2 A;  4XOO A;  4BN9 A;  1OOQ A;  4URP A;  2IFA A;  4TTC A;  3GH8 A;  3HOI A;  2R01 A;  2ISK A;  3GBH A;  3PXV A;  3GFD A;  5J6C A;  3N2S A;  2YMV A;  3EO7 A;  4XOQ A;  2I7H A;  2HAY A;  4G8S A;  2WZV A;  4DN2 A;  2WQF A;  2ISJ A;  3E39 A;  2WZW A;  1DS7 A;  3GB5 A;  1ICR A;  1NOX A;  3G14 A;  5HEI A;  1VKW A;  3K6H A;  1YKI A;  3KOQ A;  3H4O A;  1YLR A;  3GAG A;  1IDT A;  5KO7 A;  4QLY A;  1ICU A;  1KQB A;  3X21 A;  1V5Z A;  3TNZ A;  4QLX A;  2BKJ A;  3KWK A;  3E10 A; 
#chains in the Genus database with same CATH topology
 3QDL A;  5HDJ A;  1VFR A;  3HZN A;  1BKJ A;  2ISL A;  1OO6 A;  4XOM A;  3BEM A;  2FRE A;  3TO0 A;  3GR3 A;  3GE6 A;  1KQC A;  4EO3 A;  3M5K A;  5KRD A;  1OO5 A;  3EO8 A;  1YLU A;  3X22 A;  4BN8 A;  3OF4 A;  3GE5 A;  4BN7 A;  2H0U A;  3HJ9 A;  3BM1 A;  3EOF A;  4TTB A;  1ICV A;  1YWQ A;  1ZCH A;  1V5Y A;  3EK3 A;  4BN6 A;  1F5V A;  1OON A;  2B67 A;  4BNB A;  3GFA A;  5KO8 A;  1KQD A;  1NEC A;  3BM2 A;  4XOO A;  4BN9 A;  1OOQ A;  4URP A;  2IFA A;  4TTC A;  3GH8 A;  3HOI A;  2R01 A;  2ISK A;  3GBH A;  3PXV A;  3GFD A;  5J6C A;  1J6R A;  3N2S A;  2YMV A;  3EO7 A;  4XOQ A;  2I7H A;  2HAY A;  4G8S A;  2WZV A;  4DN2 A;  2WQF A;  2ISJ A;  3E39 A;  2WZW A;  1DS7 A;  3GB5 A;  1ICR A;  1NOX A;  3G14 A;  5HEI A;  1VKW A;  3K6H A;  1YKI A;  3KOQ A;  3H4O A;  1YLR A;  3GAG A;  1IDT A;  5KO7 A;  4QLY A;  1ICU A;  1KQB A;  3X21 A;  1V5Z A;  3TNZ A;  4QLX A;  2BKJ A;  3KWK A;  3E10 A; 
#chains in the Genus database with same CATH homology
 3QDL A;  5HDJ A;  1VFR A;  3HZN A;  1BKJ A;  2ISL A;  1OO6 A;  4XOM A;  3BEM A;  2FRE A;  3TO0 A;  3GR3 A;  3GE6 A;  1KQC A;  4EO3 A;  3M5K A;  5KRD A;  1OO5 A;  3EO8 A;  1YLU A;  3X22 A;  4BN8 A;  3OF4 A;  3GE5 A;  4BN7 A;  2H0U A;  3HJ9 A;  3BM1 A;  3EOF A;  4TTB A;  1ICV A;  1YWQ A;  1ZCH A;  1V5Y A;  3EK3 A;  4BN6 A;  1F5V A;  1OON A;  2B67 A;  4BNB A;  3GFA A;  5KO8 A;  1KQD A;  1NEC A;  3BM2 A;  4XOO A;  4BN9 A;  1OOQ A;  4URP A;  2IFA A;  4TTC A;  3GH8 A;  3HOI A;  2R01 A;  2ISK A;  3GBH A;  3PXV A;  3GFD A;  5J6C A;  1J6R A;  3N2S A;  2YMV A;  3EO7 A;  4XOQ A;  2I7H A;  2HAY A;  4G8S A;  2WZV A;  4DN2 A;  2WQF A;  2ISJ A;  3E39 A;  2WZW A;  1DS7 A;  3GB5 A;  1ICR A;  1NOX A;  3G14 A;  5HEI A;  1VKW A;  3K6H A;  1YKI A;  3KOQ A;  3H4O A;  1YLR A;  3GAG A;  1IDT A;  5KO7 A;  4QLY A;  1ICU A;  1KQB A;  3X21 A;  1V5Z A;  3TNZ A;  4QLX A;  2BKJ A;  3KWK A;  3E10 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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