5KO8A

Crystal structure of haliscomenobacter hydrossis iodotyrosine deiodinase (iyd) bound to fmn and mono-iodotyrosine (i-tyr)
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
218
structure length
215
Chain Sequence
AFIPYAGAQFEPEEMLSKSAEYYQFMDHRRTVREFSNRAIPLEVIENIVMTASTAPSGAHKQPWTFVVVSDPQIKAKIRQAAEKEEFESYNGNEWLEDLQPFGTDWHKPFLEIAPYLIVVFRKAYDVLPDGTQRKNYYVQESVGIACGFLLAAIHQAGLVALTHTPSPMNFLQKILQRPENERPFLLVPVGYPAEGAMVPDLQRKDKAAVMVVYH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
source organism Haliscomenobacter hydrossis (strain atcc 27775 / dsm 1100 / lmg 10767 / o)
publication title Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine Deiodinase.
pubmed doi rcsb
molecule keywords Nitroreductase
total genus 51
structure length 215
sequence length 218
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00881 Nitroreductase Nitroreductase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.109.10 Alpha Beta 3-Layer(aba) Sandwich NADH Oxidase NADH Oxidase 5ko8A00
3HOIA 3EO7A 3HZNA 4TTBA 1ZCHA 5HDJA 3GR3A 3M5KA 2B67A 4BN6A 3X22A 3HJ9A 1VKWA 1KQCA 5KO7A 1BKJA 2YMVA 5KRDA 2BKJA 1YLRA 3OF4A 3TO0A 4EO3A 2WQFA 2ISJA 2ISKA 3H4OA 1YWQA 3GFAA 1V5YA 3N2SA 3E10A 4DN2A 4QLXA 5KO8A 1OOQA 4XOOA 1OONA 4URPA 1VFRA 1NECA 1V5ZA 4TTCA 1ICUA 3GAGA 2H0UA 3EK3A 3TNZA 3GE6A 5HEIA 4QLYA 3K6HA 1KQBA 1ICVA 4BN7A 4BN9A 4G8SA 4XOMA 2WZVA 1F5VA 2HAYA 4BN8A 3KWKA 3X21A 3GE5A 3EOFA 1KQDA 2I7HA 1NOXA 3EO8A 3GH8A 2IFAA 3GBHA 5J6CA 4BNBA 3GFDA 1OO5A 3BM1A 2ISLA 3E39A 2FREA 3BM2A 3G14A 2R01A 3GB5A 2WZWA 4XOQA 3QDLA 1DS7A 3PXVA 1YLUA 3KOQA 1ICRA 1YKIA 3BEMA 1IDTA 1OO6A
chains in the Genus database with same CATH superfamily
3HOIA 3EO7A 3HZNA 4TTBA 1ZCHA 5HDJA 3GR3A 3M5KA 2B67A 4BN6A 3X22A 3HJ9A 1VKWA 1KQCA 5KO7A 1BKJA 2YMVA 5KRDA 2BKJA 1YLRA 3OF4A 3TO0A 4EO3A 2WQFA 2ISJA 2ISKA 3H4OA 1YWQA 3GFAA 1V5YA 3N2SA 3E10A 4DN2A 4QLXA 5KO8A 1OOQA 4XOOA 1OONA 4URPA 1VFRA 1NECA 1V5ZA 4TTCA 1ICUA 3GAGA 2H0UA 3EK3A 3TNZA 3GE6A 5HEIA 4QLYA 3K6HA 1KQBA 1ICVA 4BN7A 4BN9A 1J6RA 4G8SA 4XOMA 2WZVA 1F5VA 2HAYA 4BN8A 3KWKA 3X21A 3GE5A 3EOFA 1KQDA 2I7HA 1NOXA 3EO8A 3GH8A 2IFAA 3GBHA 5J6CA 4BNBA 3GFDA 1OO5A 3BM1A 2ISLA 3E39A 2FREA 3BM2A 3G14A 2R01A 3GB5A 2WZWA 4XOQA 3QDLA 1DS7A 3PXVA 1YLUA 3KOQA 1ICRA 1YKIA 3BEMA 1IDTA 1OO6A
chains in the Genus database with same CATH topology
3HOIA 3EO7A 3HZNA 4TTBA 1ZCHA 5HDJA 3GR3A 3M5KA 2B67A 4BN6A 3X22A 3HJ9A 1VKWA 1KQCA 5KO7A 1BKJA 2YMVA 5KRDA 2BKJA 1YLRA 3OF4A 3TO0A 4EO3A 2WQFA 2ISJA 2ISKA 3H4OA 1YWQA 3GFAA 1V5YA 3N2SA 3E10A 4DN2A 4QLXA 5KO8A 1OOQA 4XOOA 1OONA 4URPA 1VFRA 1NECA 1V5ZA 4TTCA 1ICUA 3GAGA 2H0UA 3EK3A 3TNZA 3GE6A 5HEIA 4QLYA 3K6HA 1KQBA 1ICVA 4BN7A 4BN9A 1J6RA 4G8SA 4XOMA 2WZVA 1F5VA 2HAYA 4BN8A 3KWKA 3X21A 3GE5A 3EOFA 1KQDA 2I7HA 1NOXA 3EO8A 3GH8A 2IFAA 3GBHA 5J6CA 4BNBA 3GFDA 1OO5A 3BM1A 2ISLA 3E39A 2FREA 3BM2A 3G14A 2R01A 3GB5A 2WZWA 4XOQA 3QDLA 1DS7A 3PXVA 1YLUA 3KOQA 1ICRA 1YKIA 3BEMA 1IDTA 1OO6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HOI A;  3EO7 A;  3HZN A;  4TTB A;  1ZCH A;  5HDJ A;  3GR3 A;  3M5K A;  2B67 A;  4BN6 A;  3X22 A;  3HJ9 A;  1VKW A;  1KQC A;  5KO7 A;  1BKJ A;  2YMV A;  5KRD A;  2BKJ A;  1YLR A;  3OF4 A;  3TO0 A;  4EO3 A;  2WQF A;  2ISJ A;  2ISK A;  3H4O A;  1YWQ A;  3GFA A;  1V5Y A;  3N2S A;  3E10 A;  4DN2 A;  4QLX A;  5KO8 A;  1OOQ A;  4XOO A;  1OON A;  4URP A;  1VFR A;  1NEC A;  1V5Z A;  4TTC A;  1ICU A;  3GAG A;  2H0U A;  3EK3 A;  3TNZ A;  3GE6 A;  5HEI A;  4QLY A;  3K6H A;  1KQB A;  1ICV A;  4BN7 A;  4BN9 A;  4G8S A;  4XOM A;  2WZV A;  1F5V A;  2HAY A;  4BN8 A;  3KWK A;  3X21 A;  3GE5 A;  3EOF A;  1KQD A;  2I7H A;  1NOX A;  3EO8 A;  3GH8 A;  2IFA A;  3GBH A;  5J6C A;  4BNB A;  3GFD A;  1OO5 A;  3BM1 A;  2ISL A;  3E39 A;  2FRE A;  3BM2 A;  3G14 A;  2R01 A;  3GB5 A;  2WZW A;  4XOQ A;  3QDL A;  1DS7 A;  3PXV A;  1YLU A;  3KOQ A;  1ICR A;  1YKI A;  3BEM A;  1IDT A;  1OO6 A; 
#chains in the Genus database with same CATH topology
 3HOI A;  3EO7 A;  3HZN A;  4TTB A;  1ZCH A;  5HDJ A;  3GR3 A;  3M5K A;  2B67 A;  4BN6 A;  3X22 A;  3HJ9 A;  1VKW A;  1KQC A;  5KO7 A;  1BKJ A;  2YMV A;  5KRD A;  2BKJ A;  1YLR A;  3OF4 A;  3TO0 A;  4EO3 A;  2WQF A;  2ISJ A;  2ISK A;  3H4O A;  1YWQ A;  3GFA A;  1V5Y A;  3N2S A;  3E10 A;  4DN2 A;  4QLX A;  5KO8 A;  1OOQ A;  4XOO A;  1OON A;  4URP A;  1VFR A;  1NEC A;  1V5Z A;  4TTC A;  1ICU A;  3GAG A;  2H0U A;  3EK3 A;  3TNZ A;  3GE6 A;  5HEI A;  4QLY A;  3K6H A;  1KQB A;  1ICV A;  4BN7 A;  4BN9 A;  1J6R A;  4G8S A;  4XOM A;  2WZV A;  1F5V A;  2HAY A;  4BN8 A;  3KWK A;  3X21 A;  3GE5 A;  3EOF A;  1KQD A;  2I7H A;  1NOX A;  3EO8 A;  3GH8 A;  2IFA A;  3GBH A;  5J6C A;  4BNB A;  3GFD A;  1OO5 A;  3BM1 A;  2ISL A;  3E39 A;  2FRE A;  3BM2 A;  3G14 A;  2R01 A;  3GB5 A;  2WZW A;  4XOQ A;  3QDL A;  1DS7 A;  3PXV A;  1YLU A;  3KOQ A;  1ICR A;  1YKI A;  3BEM A;  1IDT A;  1OO6 A; 
#chains in the Genus database with same CATH homology
 3HOI A;  3EO7 A;  3HZN A;  4TTB A;  1ZCH A;  5HDJ A;  3GR3 A;  3M5K A;  2B67 A;  4BN6 A;  3X22 A;  3HJ9 A;  1VKW A;  1KQC A;  5KO7 A;  1BKJ A;  2YMV A;  5KRD A;  2BKJ A;  1YLR A;  3OF4 A;  3TO0 A;  4EO3 A;  2WQF A;  2ISJ A;  2ISK A;  3H4O A;  1YWQ A;  3GFA A;  1V5Y A;  3N2S A;  3E10 A;  4DN2 A;  4QLX A;  5KO8 A;  1OOQ A;  4XOO A;  1OON A;  4URP A;  1VFR A;  1NEC A;  1V5Z A;  4TTC A;  1ICU A;  3GAG A;  2H0U A;  3EK3 A;  3TNZ A;  3GE6 A;  5HEI A;  4QLY A;  3K6H A;  1KQB A;  1ICV A;  4BN7 A;  4BN9 A;  1J6R A;  4G8S A;  4XOM A;  2WZV A;  1F5V A;  2HAY A;  4BN8 A;  3KWK A;  3X21 A;  3GE5 A;  3EOF A;  1KQD A;  2I7H A;  1NOX A;  3EO8 A;  3GH8 A;  2IFA A;  3GBH A;  5J6C A;  4BNB A;  3GFD A;  1OO5 A;  3BM1 A;  2ISL A;  3E39 A;  2FRE A;  3BM2 A;  3G14 A;  2R01 A;  3GB5 A;  2WZW A;  4XOQ A;  3QDL A;  1DS7 A;  3PXV A;  1YLU A;  3KOQ A;  1ICR A;  1YKI A;  3BEM A;  1IDT A;  1OO6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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