5KRDA

Crystal structure of haliscomenobacter hydrossis iodotyrosine deiodinase (iyd) bound to fmn and 2-iodophenol (2ip)
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
218
structure length
200
Chain Sequence
AFIPYAGAQFEPEEMLSKSAEYYQFMDHRRTVREFSNRAIPLEVIENIVMTASTAPSGAHKQPWTFVVVSDPQIKAKIRQAAEKEEFESDWHKPFLEIAPYLIVVFRKAYDVLPDGTQRKNYYVQESVGIACGFLLAAIHQAGLVALTHTPSPMNFLQKILQRPENERPFLLVPVGYPAEGAMVPDLQRKDKAAVMVVYH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine Deiodinase.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Haliscomenobacter hydrossis (strain atcc 27775 / dsm 1100 / lmg 10767 / o)
molecule keywords Nitroreductase
total genus 52
structure length 200
sequence length 218
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00881 Nitroreductase Nitroreductase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.109.10 Alpha Beta 3-Layer(aba) Sandwich NADH Oxidase NADH Oxidase 5krdA00
1ICVA 3K6HA 2ISJA 3KOQA 3GFAA 1V5ZA 1IDTA 4URPA 3X22A 3GH8A 4BN9A 3HZNA 1VKWA 2WQFA 3GE6A 4EO3A 3BM2A 1BKJA 1KQCA 2H0UA 4QLXA 4BN8A 4G8SA 4XOQA 1NOXA 3N2SA 3EK3A 3GR3A 3PXVA 3EO8A 1VFRA 5HDJA 3BM1A 1KQDA 3HOIA 5KO7A 1KQBA 2BKJA 1YWQA 3GFDA 2I7HA 2HAYA 3E39A 2B67A 1OO5A 3GAGA 3GBHA 5KO8A 5HEIA 1ZCHA 1OO6A 3HJ9A 2ISLA 3KWKA 4BN7A 4QLYA 4TTBA 4TTCA 4XOMA 4XOOA 3G14A 3BEMA 1YKIA 1DS7A 1ICRA 2IFAA 2R01A 4DN2A 3E10A 3H4OA 1YLUA 3EOFA 2FREA 1NECA 2WZVA 2ISKA 4BN6A 1V5YA 1F5VA 1OONA 2YMVA 3M5KA 3TNZA 3EO7A 3GB5A 3OF4A 3QDLA 3GE5A 5KRDA 1YLRA 3X21A 4BNBA 3TO0A 2WZWA 1ICUA 5J6CA 1OOQA
chains in the Genus database with same CATH superfamily
1ICVA 3K6HA 2ISJA 3KOQA 3GFAA 1V5ZA 1IDTA 1J6RA 4URPA 3X22A 3GH8A 4BN9A 3HZNA 1VKWA 2WQFA 3GE6A 4EO3A 3BM2A 1BKJA 1KQCA 2H0UA 4QLXA 4BN8A 4G8SA 4XOQA 1NOXA 3N2SA 3EK3A 3GR3A 3PXVA 3EO8A 1VFRA 5HDJA 3BM1A 1KQDA 3HOIA 5KO7A 1KQBA 2BKJA 1YWQA 3GFDA 2I7HA 2HAYA 3E39A 2B67A 1OO5A 3GAGA 3GBHA 5KO8A 5HEIA 1ZCHA 1OO6A 3HJ9A 2ISLA 3KWKA 4BN7A 4QLYA 4TTBA 4TTCA 4XOMA 4XOOA 3G14A 3BEMA 1YKIA 1DS7A 1ICRA 2IFAA 2R01A 4DN2A 3E10A 3H4OA 1YLUA 3EOFA 2FREA 1NECA 2WZVA 2ISKA 4BN6A 1V5YA 1F5VA 1OONA 2YMVA 3M5KA 3TNZA 3EO7A 3GB5A 3OF4A 3QDLA 3GE5A 5KRDA 1YLRA 3X21A 4BNBA 3TO0A 2WZWA 1ICUA 5J6CA 1OOQA
chains in the Genus database with same CATH topology
1ICVA 3K6HA 2ISJA 3KOQA 3GFAA 1V5ZA 1IDTA 1J6RA 4URPA 3X22A 3GH8A 4BN9A 3HZNA 1VKWA 2WQFA 3GE6A 4EO3A 3BM2A 1BKJA 1KQCA 2H0UA 4QLXA 4BN8A 4G8SA 4XOQA 1NOXA 3N2SA 3EK3A 3GR3A 3PXVA 3EO8A 1VFRA 5HDJA 3BM1A 1KQDA 3HOIA 5KO7A 1KQBA 2BKJA 1YWQA 3GFDA 2I7HA 2HAYA 3E39A 2B67A 1OO5A 3GAGA 3GBHA 5KO8A 5HEIA 1ZCHA 1OO6A 3HJ9A 2ISLA 3KWKA 4BN7A 4QLYA 4TTBA 4TTCA 4XOMA 4XOOA 3G14A 3BEMA 1YKIA 1DS7A 1ICRA 2IFAA 2R01A 4DN2A 3E10A 3H4OA 1YLUA 3EOFA 2FREA 1NECA 2WZVA 2ISKA 4BN6A 1V5YA 1F5VA 1OONA 2YMVA 3M5KA 3TNZA 3EO7A 3GB5A 3OF4A 3QDLA 3GE5A 5KRDA 1YLRA 3X21A 4BNBA 3TO0A 2WZWA 1ICUA 5J6CA 1OOQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ICV A;  3K6H A;  2ISJ A;  3KOQ A;  3GFA A;  1V5Z A;  1IDT A;  4URP A;  3X22 A;  3GH8 A;  4BN9 A;  3HZN A;  1VKW A;  2WQF A;  3GE6 A;  4EO3 A;  3BM2 A;  1BKJ A;  1KQC A;  2H0U A;  4QLX A;  4BN8 A;  4G8S A;  4XOQ A;  1NOX A;  3N2S A;  3EK3 A;  3GR3 A;  3PXV A;  3EO8 A;  1VFR A;  5HDJ A;  3BM1 A;  1KQD A;  3HOI A;  5KO7 A;  1KQB A;  2BKJ A;  1YWQ A;  3GFD A;  2I7H A;  2HAY A;  3E39 A;  2B67 A;  1OO5 A;  3GAG A;  3GBH A;  5KO8 A;  5HEI A;  1ZCH A;  1OO6 A;  3HJ9 A;  2ISL A;  3KWK A;  4BN7 A;  4QLY A;  4TTB A;  4TTC A;  4XOM A;  4XOO A;  3G14 A;  3BEM A;  1YKI A;  1DS7 A;  1ICR A;  2IFA A;  2R01 A;  4DN2 A;  3E10 A;  3H4O A;  1YLU A;  3EOF A;  2FRE A;  1NEC A;  2WZV A;  2ISK A;  4BN6 A;  1V5Y A;  1F5V A;  1OON A;  2YMV A;  3M5K A;  3TNZ A;  3EO7 A;  3GB5 A;  3OF4 A;  3QDL A;  3GE5 A;  5KRD A;  1YLR A;  3X21 A;  4BNB A;  3TO0 A;  2WZW A;  1ICU A;  5J6C A;  1OOQ A; 
#chains in the Genus database with same CATH topology
 1ICV A;  3K6H A;  2ISJ A;  3KOQ A;  3GFA A;  1V5Z A;  1IDT A;  1J6R A;  4URP A;  3X22 A;  3GH8 A;  4BN9 A;  3HZN A;  1VKW A;  2WQF A;  3GE6 A;  4EO3 A;  3BM2 A;  1BKJ A;  1KQC A;  2H0U A;  4QLX A;  4BN8 A;  4G8S A;  4XOQ A;  1NOX A;  3N2S A;  3EK3 A;  3GR3 A;  3PXV A;  3EO8 A;  1VFR A;  5HDJ A;  3BM1 A;  1KQD A;  3HOI A;  5KO7 A;  1KQB A;  2BKJ A;  1YWQ A;  3GFD A;  2I7H A;  2HAY A;  3E39 A;  2B67 A;  1OO5 A;  3GAG A;  3GBH A;  5KO8 A;  5HEI A;  1ZCH A;  1OO6 A;  3HJ9 A;  2ISL A;  3KWK A;  4BN7 A;  4QLY A;  4TTB A;  4TTC A;  4XOM A;  4XOO A;  3G14 A;  3BEM A;  1YKI A;  1DS7 A;  1ICR A;  2IFA A;  2R01 A;  4DN2 A;  3E10 A;  3H4O A;  1YLU A;  3EOF A;  2FRE A;  1NEC A;  2WZV A;  2ISK A;  4BN6 A;  1V5Y A;  1F5V A;  1OON A;  2YMV A;  3M5K A;  3TNZ A;  3EO7 A;  3GB5 A;  3OF4 A;  3QDL A;  3GE5 A;  5KRD A;  1YLR A;  3X21 A;  4BNB A;  3TO0 A;  2WZW A;  1ICU A;  5J6C A;  1OOQ A; 
#chains in the Genus database with same CATH homology
 1ICV A;  3K6H A;  2ISJ A;  3KOQ A;  3GFA A;  1V5Z A;  1IDT A;  1J6R A;  4URP A;  3X22 A;  3GH8 A;  4BN9 A;  3HZN A;  1VKW A;  2WQF A;  3GE6 A;  4EO3 A;  3BM2 A;  1BKJ A;  1KQC A;  2H0U A;  4QLX A;  4BN8 A;  4G8S A;  4XOQ A;  1NOX A;  3N2S A;  3EK3 A;  3GR3 A;  3PXV A;  3EO8 A;  1VFR A;  5HDJ A;  3BM1 A;  1KQD A;  3HOI A;  5KO7 A;  1KQB A;  2BKJ A;  1YWQ A;  3GFD A;  2I7H A;  2HAY A;  3E39 A;  2B67 A;  1OO5 A;  3GAG A;  3GBH A;  5KO8 A;  5HEI A;  1ZCH A;  1OO6 A;  3HJ9 A;  2ISL A;  3KWK A;  4BN7 A;  4QLY A;  4TTB A;  4TTC A;  4XOM A;  4XOO A;  3G14 A;  3BEM A;  1YKI A;  1DS7 A;  1ICR A;  2IFA A;  2R01 A;  4DN2 A;  3E10 A;  3H4O A;  1YLU A;  3EOF A;  2FRE A;  1NEC A;  2WZV A;  2ISK A;  4BN6 A;  1V5Y A;  1F5V A;  1OON A;  2YMV A;  3M5K A;  3TNZ A;  3EO7 A;  3GB5 A;  3OF4 A;  3QDL A;  3GE5 A;  5KRD A;  1YLR A;  3X21 A;  4BNB A;  3TO0 A;  2WZW A;  1ICU A;  5J6C A;  1OOQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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