5TARB

Crystal structure of farnesylated and methylated kras4b in complex with pde-delta (crystal form ii - with ordered hypervariable region)
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
148
structure length
148
Chain Sequence
AKDERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSTEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLLVSTSRVRLFYV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of recognition of farnesylated and methylated KRAS4b by PDE delta.
pubmed doi rcsb
molecule tags Oncoprotein
source organism Homo sapiens
molecule keywords GTPase KRas
total genus 42
structure length 148
sequence length 148
ec nomenclature
pdb deposition date 2016-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF05351 GMP_PDE_delta GMP-PDE, delta subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.50.40 Mainly Beta Distorted Sandwich Coagulation Factor XIII; Chain A, domain 1 GMP phosphodiesterase, delta subunit 5tarB00
4GOJC 1KSHB 5TARB 3RBQA 5TB5B 4JHPB 5E80A 4JV6B 4GOKC 1KSGB 3GQQA 1KSJB 3T5IA 5L7KA 5E8FA 4JVFB 4JVBB 4JV8B 5F2UA 3T5GB
chains in the Genus database with same CATH superfamily
4ALTA 4EISA 4GOJC 5IJUA 5TARB 3RBQA 4A02A 5AA7A 5TB5B 5HGUA 2JHVA 4GOKC 3ZUDA 5FTZA 4ALSA 2JHUA 4GBOA 4F38B 4ALRA 4ALEA 1FSTA 4OY7A 1DOAB 5F2UA 5ACIA 1KSHB 2BXWA 2R5OA 2YOXA 1RHOA 4OY8A 1HH4D 5DQ8A 1KSGB 3GQQA 2BEMA 5FOHA 5L7KA 1GDFA 4LN0A 1DS6B 3EIIA 4D7UA 4JV8B 3T5GB 1AJWA 2JHTA 1FT0A 4ALQA 2LHSA 4RE1A 3L15A 5ACJA 3EJAA 4OY6A 4B5QA 1KSJB 3T5IA 2VTCA 2JHXA 5E8FA 5FJQA 4JVFB 2YETA 2YOYA 4JVBB 2YOWA 4QI8A 2JHYA 5ACHA 1QVYA 2BENA 4JHPB 4EISB 3UAMA 5HNPA 5ACFA 5DQEA 5ACGA 2JHZA 5E80A 4JV6B 4EIRA 3JUAA 4MAHA 1KMTA 1FSOA 3KYSA 4FMRA 4D7VA 4MAIA 5EMWA 5EMVA 5HNOA 2JHWA 4ALCA 2JI0A 2XWXA 2JHSA 1FT3A
chains in the Genus database with same CATH topology
4GOJC 1KSHB 5TARB 3RBQA 5TB5B 4JHPB 5E80A 4JV6B 4GOKC 1KSGB 3GQQA 1KSJB 3T5IA 5L7KA 5E8FA 4JVFB 4JVBB 4JV8B 5F2UA 3T5GB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GOJ C;  1KSH B;  5TAR B;  3RBQ A;  5TB5 B;  4JHP B;  5E80 A;  4JV6 B;  4GOK C;  1KSG B;  3GQQ A;  1KSJ B;  3T5I A;  5L7K A;  5E8F A;  4JVF B;  4JVB B;  4JV8 B;  5F2U A;  3T5G B; 
#chains in the Genus database with same CATH topology
 4ALT A;  4EIS A;  4GOJ C;  5IJU A;  5TAR B;  3RBQ A;  4A02 A;  5AA7 A;  5TB5 B;  5HGU A;  2JHV A;  4GOK C;  3ZUD A;  5FTZ A;  4ALS A;  2JHU A;  4GBO A;  4F38 B;  4ALR A;  4ALE A;  1FST A;  4OY7 A;  1DOA B;  5F2U A;  5ACI A;  1KSH B;  2BXW A;  2R5O A;  2YOX A;  1RHO A;  4OY8 A;  1HH4 D;  5DQ8 A;  1KSG B;  3GQQ A;  2BEM A;  5FOH A;  5L7K A;  1GDF A;  4LN0 A;  1DS6 B;  3EII A;  4D7U A;  4JV8 B;  3T5G B;  1AJW A;  2JHT A;  1FT0 A;  4ALQ A;  2LHS A;  4RE1 A;  3L15 A;  5ACJ A;  3EJA A;  4OY6 A;  4B5Q A;  1KSJ B;  3T5I A;  2VTC A;  2JHX A;  5E8F A;  5FJQ A;  4JVF B;  2YET A;  2YOY A;  4JVB B;  2YOW A;  4QI8 A;  2JHY A;  5ACH A;  1QVY A;  2BEN A;  4JHP B;  4EIS B;  3UAM A;  5HNP A;  5ACF A;  5DQE A;  5ACG A;  2JHZ A;  5E80 A;  4JV6 B;  4EIR A;  3JUA A;  4MAH A;  1KMT A;  1FSO A;  3KYS A;  4FMR A;  4D7V A;  4MAI A;  5EMW A;  5EMV A;  5HNO A;  2JHW A;  4ALC A;  2JI0 A;  2XWX A;  2JHS A;  1FT3 A; 
#chains in the Genus database with same CATH homology
 4GOJ C;  1KSH B;  5TAR B;  3RBQ A;  5TB5 B;  4JHP B;  5E80 A;  4JV6 B;  4GOK C;  1KSG B;  3GQQ A;  1KSJ B;  3T5I A;  5L7K A;  5E8F A;  4JVF B;  4JVB B;  4JV8 B;  5F2U A;  3T5G B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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