5TDHG

The crystal structure of the dominant negative mutant g protein alpha(i)-1-beta-1-gamma-2 g203a/a326s
Total Genus 14
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
55
structure length
55
Chain Sequence
SIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title The structural basis of the dominant negative phenotype of the G alpha i1 beta 1 gamma 2 G203A/A326S heterotrimer
pubmed doi rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords Guanine nucleotide-binding protein G(i) subunit alpha-1
total genus 14
structure length 55
sequence length 55
chains with identical sequence K
ec nomenclature
pdb deposition date 2016-09-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 5tdhG00
3PVUG 3KRXG 5TDHG 4MK0G 1GG2G 1OMWG 1B9YB 3CIKG 3PVWG 3V5WG 5HE0G 2BCJG 5KDOG 1GP2G 1A0RG 1GOTG 5HE2G 1B9XB 3KRWG 2TRCG 4KFMG 1TBGE 3AH8G 3PSCG 5HE1G 1XHMB 5HE3G 2PBIA 4PNKG 3SN6G
chains in the Genus database with same CATH superfamily
3PVUG 3KRXG 5TDHG 1HFES 4MK0G 1GG2G 1OMWG 1B9YB 3CIKG 3PVWG 3V5WG 5HE0G 2BCJG 1IOJA 5KDOG 1GP2G 1A0RG 1GOTG 5HE2G 1B9XB 3KRWG 2TRCG 4KFMG 1TBGE 3AH8G 3PSCG 5HE1G 1XHMB 5HE3G 2PBIA 4PNKG 3SN6G
chains in the Genus database with same CATH topology
3PVUG 3KRXG 5TDHG 4MK0G 1GG2G 1OMWG 1B9YB 3CIKG 3PVWG 3V5WG 5HE0G 2BCJG 5KDOG 1GP2G 1A0RG 1GOTG 5HE2G 1B9XB 3KRWG 2TRCG 4KFMG 1TBGE 3AH8G 3PSCG 5HE1G 1XHMB 5HE3G 2PBIA 4PNKG 3SN6G
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PVU G;  3KRX G;  5TDH G;  4MK0 G;  1GG2 G;  1OMW G;  1B9Y B;  3CIK G;  3PVW G;  3V5W G;  5HE0 G;  2BCJ G;  5KDO G;  1GP2 G;  1A0R G;  1GOT G;  5HE2 G;  1B9X B;  3KRW G;  2TRC G;  4KFM G;  1TBG E;  3AH8 G;  3PSC G;  5HE1 G;  1XHM B;  5HE3 G;  2PBI A;  4PNK G;  3SN6 G; 
#chains in the Genus database with same CATH topology
 3PVU G;  3KRX G;  5TDH G;  1HFE S;  4MK0 G;  1GG2 G;  1OMW G;  1B9Y B;  3CIK G;  3PVW G;  3V5W G;  5HE0 G;  2BCJ G;  1IOJ A;  5KDO G;  1GP2 G;  1A0R G;  1GOT G;  5HE2 G;  1B9X B;  3KRW G;  2TRC G;  4KFM G;  1TBG E;  3AH8 G;  3PSC G;  5HE1 G;  1XHM B;  5HE3 G;  2PBI A;  4PNK G;  3SN6 G; 
#chains in the Genus database with same CATH homology
 3PVU G;  3KRX G;  5TDH G;  4MK0 G;  1GG2 G;  1OMW G;  1B9Y B;  3CIK G;  3PVW G;  3V5W G;  5HE0 G;  2BCJ G;  5KDO G;  1GP2 G;  1A0R G;  1GOT G;  5HE2 G;  1B9X B;  3KRW G;  2TRC G;  4KFM G;  1TBG E;  3AH8 G;  3PSC G;  5HE1 G;  1XHM B;  5HE3 G;  2PBI A;  4PNK G;  3SN6 G; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...