5TDHG

The crystal structure of the dominant negative mutant g protein alpha(i)-1-beta-1-gamma-2 g203a/a326s
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
55
structure length
55
Chain Sequence
SIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structural basis of the dominant negative phenotype of the G alpha i1 beta 1 gamma 2 G203A/A326S heterotrimer
pubmed doi rcsb
molecule keywords Guanine nucleotide-binding protein G(i) subunit alpha-1
molecule tags Cell cycle
source organism Homo sapiens
total genus 14
structure length 55
sequence length 55
chains with identical sequence K
ec nomenclature
pdb deposition date 2016-09-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 5tdhG00
5HE0G 5HE1G 2TRCG 1A0RG 1B9YB 3KRXG 2BCJG 1B9XB 1OMWG 2PBIA 3CIKG 5HE3G 5HE2G 4PNKG 5KDOG 3PSCG 1GOTG 5TDHG 3PVUG 3PVWG 4MK0G 4KFMG 1GG2G 1XHMB 3V5WG 1GP2G 3AH8G 3KRWG 3SN6G 1TBGE
chains in the Genus database with same CATH superfamily
5HE0G 5HE1G 2TRCG 1A0RG 1B9YB 3KRXG 2BCJG 1B9XB 1OMWG 2PBIA 3CIKG 5HE3G 5HE2G 4PNKG 5KDOG 3PSCG 1GOTG 5TDHG 1HFES 3PVUG 1IOJA 3PVWG 4MK0G 4KFMG 1GG2G 1XHMB 3V5WG 1GP2G 3AH8G 3KRWG 3SN6G 1TBGE
chains in the Genus database with same CATH topology
5HE0G 5HE1G 2TRCG 1A0RG 1B9YB 3KRXG 2BCJG 1B9XB 1OMWG 2PBIA 3CIKG 5HE3G 5HE2G 4PNKG 5KDOG 3PSCG 1GOTG 5TDHG 3PVUG 3PVWG 4MK0G 4KFMG 1GG2G 1XHMB 3V5WG 1GP2G 3AH8G 3KRWG 3SN6G 1TBGE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HE0 G;  5HE1 G;  2TRC G;  1A0R G;  1B9Y B;  3KRX G;  2BCJ G;  1B9X B;  1OMW G;  2PBI A;  3CIK G;  5HE3 G;  5HE2 G;  4PNK G;  5KDO G;  3PSC G;  1GOT G;  5TDH G;  3PVU G;  3PVW G;  4MK0 G;  4KFM G;  1GG2 G;  1XHM B;  3V5W G;  1GP2 G;  3AH8 G;  3KRW G;  3SN6 G;  1TBG E; 
#chains in the Genus database with same CATH topology
 5HE0 G;  5HE1 G;  2TRC G;  1A0R G;  1B9Y B;  3KRX G;  2BCJ G;  1B9X B;  1OMW G;  2PBI A;  3CIK G;  5HE3 G;  5HE2 G;  4PNK G;  5KDO G;  3PSC G;  1GOT G;  5TDH G;  1HFE S;  3PVU G;  1IOJ A;  3PVW G;  4MK0 G;  4KFM G;  1GG2 G;  1XHM B;  3V5W G;  1GP2 G;  3AH8 G;  3KRW G;  3SN6 G;  1TBG E; 
#chains in the Genus database with same CATH homology
 5HE0 G;  5HE1 G;  2TRC G;  1A0R G;  1B9Y B;  3KRX G;  2BCJ G;  1B9X B;  1OMW G;  2PBI A;  3CIK G;  5HE3 G;  5HE2 G;  4PNK G;  5KDO G;  3PSC G;  1GOT G;  5TDH G;  3PVU G;  3PVW G;  4MK0 G;  4KFM G;  1GG2 G;  1XHM B;  3V5W G;  1GP2 G;  3AH8 G;  3KRW G;  3SN6 G;  1TBG E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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