5TDHG

The crystal structure of the dominant negative mutant g protein alpha(i)-1-beta-1-gamma-2 g203a/a326s
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
55
structure length
55
Chain Sequence
SIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structural basis of the dominant negative phenotype of the G alpha i1 beta 1 gamma 2 G203A/A326S heterotrimer
pubmed doi rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords Guanine nucleotide-binding protein G(i) subunit alpha-1
total genus 14
structure length 55
sequence length 55
chains with identical sequence K
ec nomenclature
pdb deposition date 2016-09-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 5tdhG00
4KFMG 1GP2G 3PVUG 3V5WG 5HE3G 1B9XB 4MK0G 1B9YB 1XHMB 1A0RG 1TBGE 1GG2G 3SN6G 3CIKG 5TDHG 5HE0G 1GOTG 3PVWG 5HE2G 3PSCG 5HE1G 5KDOG 2PBIA 2BCJG 3KRXG 2TRCG 3KRWG 1OMWG 4PNKG 3AH8G
chains in the Genus database with same CATH superfamily
4KFMG 1GP2G 3PVUG 3V5WG 5HE3G 1B9XB 4MK0G 1B9YB 1XHMB 1A0RG 1IOJA 1TBGE 1GG2G 3SN6G 3CIKG 5TDHG 1HFES 5HE0G 1GOTG 3PVWG 5HE2G 3PSCG 5HE1G 5KDOG 2PBIA 2BCJG 3KRXG 2TRCG 3KRWG 1OMWG 4PNKG 3AH8G
chains in the Genus database with same CATH topology
4KFMG 1GP2G 3PVUG 3V5WG 5HE3G 1B9XB 4MK0G 1B9YB 1XHMB 1A0RG 1TBGE 1GG2G 3SN6G 3CIKG 5TDHG 5HE0G 1GOTG 3PVWG 5HE2G 3PSCG 5HE1G 5KDOG 2PBIA 2BCJG 3KRXG 2TRCG 3KRWG 1OMWG 4PNKG 3AH8G
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KFM G;  1GP2 G;  3PVU G;  3V5W G;  5HE3 G;  1B9X B;  4MK0 G;  1B9Y B;  1XHM B;  1A0R G;  1TBG E;  1GG2 G;  3SN6 G;  3CIK G;  5TDH G;  5HE0 G;  1GOT G;  3PVW G;  5HE2 G;  3PSC G;  5HE1 G;  5KDO G;  2PBI A;  2BCJ G;  3KRX G;  2TRC G;  3KRW G;  1OMW G;  4PNK G;  3AH8 G; 
#chains in the Genus database with same CATH topology
 4KFM G;  1GP2 G;  3PVU G;  3V5W G;  5HE3 G;  1B9X B;  4MK0 G;  1B9Y B;  1XHM B;  1A0R G;  1IOJ A;  1TBG E;  1GG2 G;  3SN6 G;  3CIK G;  5TDH G;  1HFE S;  5HE0 G;  1GOT G;  3PVW G;  5HE2 G;  3PSC G;  5HE1 G;  5KDO G;  2PBI A;  2BCJ G;  3KRX G;  2TRC G;  3KRW G;  1OMW G;  4PNK G;  3AH8 G; 
#chains in the Genus database with same CATH homology
 4KFM G;  1GP2 G;  3PVU G;  3V5W G;  5HE3 G;  1B9X B;  4MK0 G;  1B9Y B;  1XHM B;  1A0R G;  1TBG E;  1GG2 G;  3SN6 G;  3CIK G;  5TDH G;  5HE0 G;  1GOT G;  3PVW G;  5HE2 G;  3PSC G;  5HE1 G;  5KDO G;  2PBI A;  2BCJ G;  3KRX G;  2TRC G;  3KRW G;  1OMW G;  4PNK G;  3AH8 G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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