1A59A

Cold-active citrate synthase
Total Genus 133
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
133
sequence length
377
structure length
377
Chain Sequence
EPTIHKGLAGVTADVTAISKVNSDTNSLLYRGYPVQELAAKCSFEQVAYLLWNSELPNDSELKAFVNFERSHRKLDENVKGAIDLLSTACHPMDVARTAVSVLGANHARAQDSSPEANLEKAMSLLATFPSVVAYDQRRRRGEELIEPREDLDYSANFLWMTFGEEAAPEVVEAFNVSMILYAEHSFNASTFTARVITSTLADLHSAVTGAIGALKGPLHGGANEAVMHTFEEIGIRKDESLDEAATRSKAWMVDALAQKKKVMGFGHRVYKNGDSRVPTMKSALDAMIKHYDRPEMLGLYNGLEAAMEEAKQIKPNLDYPAGPTYNLMGFDTEMFTPLFIAARITGWTAHIMEQVADNALIRPLSEYNGPEQRQVP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural adaptations of the cold-active citrate synthase from an Antarctic bacterium.
pubmed doi rcsb
molecule tags Cold-activity
source organism Antarctic bacterium ds2-3r
molecule keywords CITRATE SYNTHASE
total genus 133
structure length 377
sequence length 377
ec nomenclature ec 2.3.3.16: Citrate synthase (unknown stereospecificity).
pdb deposition date 1998-02-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00285 Citrate_synt Citrate synthase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.230.10 Mainly Alpha Orthogonal Bundle Cytochrome p450-Terp; domain 2 Cytochrome P450-Terp, domain 2 1a59A02
1.10.580.10 Mainly Alpha Orthogonal Bundle Citrate Synthase; domain 1 Citrate Synthase, domain 1 1a59A01
1VGPA 2IFCA 1O7XA 2P2WA 1A59A 4JAGA 1CSSA 4JADA 1OWCA 1IOMA 3MSUA 5CSCB 2CSCA 2R26A 1CSCA 3O8JA 6CTSA 5CSCA 4XGHA 3HWKA 4E6YA 1AL6A 3CSCA 2CTSA 4JAFA 4CTSA 3TQGA 4TVMA 4JAEA 1IXEA 2C6XA 4YBOA 2H12A 4CSCA 6CSCA 1CSHA 1AMZA 1CSRA 1NXEA 3ENJA 1CSIA 1VGMA 5CTSA 2R9EA 1CTSA 4G6BA 1OWBA 1AJ8A 1NXGA 2IBPA
chains in the Genus database with same CATH superfamily
1VGPA 2IFCA 1O7XA 2P2WA 1A59A 4JAGA 1CSSA 4JADA 1OWCA 1IOMA 3MSUA 5CSCB 2CSCA 2R26A 1CSCA 3O8JA 6CTSA 5CSCA 4XGHA 3HWKA 4E6YA 1AL6A 3CSCA 2CTSA 4JAFA 4CTSA 4TVMA 3TQGA 4JAEA 1IXEA 2C6XA 4YBOA 2H12A 4CSCA 6CSCA 1CSHA 1AMZA 1CSRA 1NXEA 3ENJA 1CSIA 1VGMA 5CTSA 2R9EA 1CTSA 4G6BA 1OWBA 1AJ8A 1NXGA 2IBPA
chains in the Genus database with same CATH topology
1VGPA 2IFCA 1O7XA 2P2WA 1A59A 4JAGA 1CSSA 4JADA 1OWCA 1IOMA 3MSUA 5CSCB 2CSCA 2R26A 1CSCA 3O8JA 6CTSA 5CSCA 4XGHA 3HWKA 4E6YA 1AL6A 3CSCA 2CTSA 4JAFA 4CTSA 3TQGA 4TVMA 4JAEA 1IXEA 2C6XA 4YBOA 2H12A 4CSCA 6CSCA 1CSHA 1AMZA 1CSRA 1NXEA 3ENJA 1CSIA 1VGMA 5CTSA 2R9EA 1CTSA 4G6BA 1OWBA 1AJ8A 1NXGA 2IBPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VGP A;  2IFC A;  1O7X A;  2P2W A;  1A59 A;  4JAG A;  1CSS A;  4JAD A;  1OWC A;  1IOM A;  3MSU A;  5CSC B;  2CSC A;  2R26 A;  1CSC A;  3O8J A;  6CTS A;  5CSC A;  4XGH A;  3HWK A;  4E6Y A;  1AL6 A;  3CSC A;  2CTS A;  4JAF A;  4CTS A;  3TQG A;  4TVM A;  4JAE A;  1IXE A;  2C6X A;  4YBO A;  2H12 A;  4CSC A;  6CSC A;  1CSH A;  1AMZ A;  1CSR A;  1NXE A;  3ENJ A;  1CSI A;  1VGM A;  5CTS A;  2R9E A;  1CTS A;  4G6B A;  1OWB A;  1AJ8 A;  1NXG A;  2IBP A; 
#chains in the Genus database with same CATH topology
 1VGP A;  2IFC A;  1O7X A;  2P2W A;  1A59 A;  4JAG A;  1CSS A;  4JAD A;  1OWC A;  1IOM A;  3MSU A;  5CSC B;  2CSC A;  2R26 A;  1CSC A;  3O8J A;  6CTS A;  5CSC A;  4XGH A;  3HWK A;  4E6Y A;  1AL6 A;  3CSC A;  2CTS A;  4JAF A;  4CTS A;  4TVM A;  3TQG A;  4JAE A;  1IXE A;  2C6X A;  4YBO A;  2H12 A;  4CSC A;  6CSC A;  1CSH A;  1AMZ A;  1CSR A;  1NXE A;  3ENJ A;  1CSI A;  1VGM A;  5CTS A;  2R9E A;  1CTS A;  4G6B A;  1OWB A;  1AJ8 A;  1NXG A;  2IBP A; 
#chains in the Genus database with same CATH homology
 1VGP A;  2IFC A;  1O7X A;  2P2W A;  1A59 A;  4JAG A;  1CSS A;  4JAD A;  1OWC A;  1IOM A;  3MSU A;  5CSC B;  2CSC A;  2R26 A;  1CSC A;  3O8J A;  6CTS A;  5CSC A;  4XGH A;  3HWK A;  4E6Y A;  1AL6 A;  3CSC A;  2CTS A;  4JAF A;  4CTS A;  3TQG A;  4TVM A;  4JAE A;  1IXE A;  2C6X A;  4YBO A;  2H12 A;  4CSC A;  6CSC A;  1CSH A;  1AMZ A;  1CSR A;  1NXE A;  3ENJ A;  1CSI A;  1VGM A;  5CTS A;  2R9E A;  1CTS A;  4G6B A;  1OWB A;  1AJ8 A;  1NXG A;  2IBP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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