4CSCA

Structure of ternary complexes of citrate synthase with d-and l-malate: mechanistic implications
Total Genus 144
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
144
sequence length
433
structure length
429
Chain Sequence
ASSTNLKDVLAALIPKEQARIKTFRQQHGGTALGQITVDMSYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKGGGGEPLPEGLFWLLVTGQIPTGAQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGILRTKYWEMVYESAMDLIAKLPCVAAKIYRNLYRAGSSIGAIDSKLDWSHNFTNMLGYTDAQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLGWLAQLQKAAGADASLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPGDPMFKLVAQLYKIVPNVLLEQGAAANPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLIAL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 1.9-A structures of ternary complexes of citrate synthase with D- and L-malate: mechanistic implications.
pubmed doi rcsb
molecule keywords CITRATE SYNTHASE
molecule tags Oxo-acid-lyase
source organism Gallus gallus
total genus 144
structure length 429
sequence length 433
ec nomenclature ec 2.3.3.1: Citrate (Si)-synthase.
pdb deposition date 1990-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00285 Citrate_synt Citrate synthase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.230.10 Mainly Alpha Orthogonal Bundle Cytochrome p450-Terp; domain 2 Cytochrome P450-Terp, domain 2 4cscA02
1.10.580.10 Mainly Alpha Orthogonal Bundle Citrate Synthase; domain 1 Citrate Synthase, domain 1 4cscA01
4JAGA 2C6XA 2IBPA 1AL6A 1OWCA 1CSSA 1NXEA 3CSCA 6CSCA 3TQGA 1CSCA 2CTSA 2R26A 1IXEA 4CTSA 1CTSA 4G6BA 3ENJA 2IFCA 2R9EA 4JAEA 4YBOA 4JAFA 3O8JA 5CSCA 6CTSA 1AMZA 2H12A 4XGHA 1CSIA 2CSCA 1VGMA 1CSHA 4E6YA 1NXGA 3MSUA 4JADA 1A59A 4TVMA 1IOMA 2P2WA 5CTSA 5CSCB 1O7XA 1OWBA 4CSCA 3HWKA 1CSRA 1AJ8A 1VGPA
chains in the Genus database with same CATH superfamily
4JAGA 2C6XA 2IBPA 1AL6A 1OWCA 1CSSA 1NXEA 3CSCA 6CSCA 3TQGA 1CSCA 2CTSA 2R26A 1IXEA 4CTSA 1CTSA 4G6BA 3ENJA 2IFCA 2R9EA 4JAEA 4YBOA 4JAFA 3O8JA 5CSCA 6CTSA 1AMZA 2H12A 4XGHA 1CSIA 2CSCA 1VGMA 1CSHA 4E6YA 1NXGA 3MSUA 4JADA 1A59A 4TVMA 1IOMA 2P2WA 5CTSA 5CSCB 1O7XA 1OWBA 4CSCA 3HWKA 1CSRA 1AJ8A 1VGPA
chains in the Genus database with same CATH topology
4JAGA 2C6XA 2IBPA 1AL6A 1OWCA 1CSSA 1NXEA 3CSCA 6CSCA 3TQGA 1CSCA 2CTSA 2R26A 1IXEA 4CTSA 1CTSA 4G6BA 3ENJA 2IFCA 2R9EA 4JAEA 4YBOA 4JAFA 3O8JA 5CSCA 6CTSA 1AMZA 2H12A 4XGHA 1CSIA 2CSCA 1VGMA 1CSHA 4E6YA 1NXGA 3MSUA 4JADA 1A59A 4TVMA 1IOMA 2P2WA 5CTSA 5CSCB 1O7XA 1OWBA 4CSCA 3HWKA 1CSRA 1AJ8A 1VGPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JAG A;  2C6X A;  2IBP A;  1AL6 A;  1OWC A;  1CSS A;  1NXE A;  3CSC A;  6CSC A;  3TQG A;  1CSC A;  2CTS A;  2R26 A;  1IXE A;  4CTS A;  1CTS A;  4G6B A;  3ENJ A;  2IFC A;  2R9E A;  4JAE A;  4YBO A;  4JAF A;  3O8J A;  5CSC A;  6CTS A;  1AMZ A;  2H12 A;  4XGH A;  1CSI A;  2CSC A;  1VGM A;  1CSH A;  4E6Y A;  1NXG A;  3MSU A;  4JAD A;  1A59 A;  4TVM A;  1IOM A;  2P2W A;  5CTS A;  5CSC B;  1O7X A;  1OWB A;  4CSC A;  3HWK A;  1CSR A;  1AJ8 A;  1VGP A; 
#chains in the Genus database with same CATH topology
 4JAG A;  2C6X A;  2IBP A;  1AL6 A;  1OWC A;  1CSS A;  1NXE A;  3CSC A;  6CSC A;  3TQG A;  1CSC A;  2CTS A;  2R26 A;  1IXE A;  4CTS A;  1CTS A;  4G6B A;  3ENJ A;  2IFC A;  2R9E A;  4JAE A;  4YBO A;  4JAF A;  3O8J A;  5CSC A;  6CTS A;  1AMZ A;  2H12 A;  4XGH A;  1CSI A;  2CSC A;  1VGM A;  1CSH A;  4E6Y A;  1NXG A;  3MSU A;  4JAD A;  1A59 A;  4TVM A;  1IOM A;  2P2W A;  5CTS A;  5CSC B;  1O7X A;  1OWB A;  4CSC A;  3HWK A;  1CSR A;  1AJ8 A;  1VGP A; 
#chains in the Genus database with same CATH homology
 4JAG A;  2C6X A;  2IBP A;  1AL6 A;  1OWC A;  1CSS A;  1NXE A;  3CSC A;  6CSC A;  3TQG A;  1CSC A;  2CTS A;  2R26 A;  1IXE A;  4CTS A;  1CTS A;  4G6B A;  3ENJ A;  2IFC A;  2R9E A;  4JAE A;  4YBO A;  4JAF A;  3O8J A;  5CSC A;  6CTS A;  1AMZ A;  2H12 A;  4XGH A;  1CSI A;  2CSC A;  1VGM A;  1CSH A;  4E6Y A;  1NXG A;  3MSU A;  4JAD A;  1A59 A;  4TVM A;  1IOM A;  2P2W A;  5CTS A;  5CSC B;  1O7X A;  1OWB A;  4CSC A;  3HWK A;  1CSR A;  1AJ8 A;  1VGP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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