1IOMA

Crystal structure of citrate synthase from thermus thermophilus hb8
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
374
structure length
374
Chain Sequence
VARGLEGVLFTESRMCYIDGQQGKLYYYGIPIQELAEKSSFEETTFLLLHGRLPRRQELEEFSAALARRRALPAHLLESFKRYPVSAHPMSFLRTAVSEFGMLDPTEGDISREALYEKGLDLIAKFATIVAANKRLKEGKEPIPPREDLSHAANFLYMANGVEPSPEQARLMDAALILHAEHGFNASTFTAIAAFSTETDLYSAITAAVASLKGPRHGGANEAVMRMIQEIGTPERAREWVREKLAKKERIMGMGHRVYKAFDPRAGVLEKLARLVAEKHGHSKEYQILKIVEEEAGKVLNPRGIYPNVDFYSGVVYSDLGFSLEFFTPIFAVARISGWVGHILEYQELDNRLLRPGAKYVGELDVPYVPLEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural comparison between the open and closed forms of citrate synthase from Thermus thermophilus HB8
doi rcsb
molecule keywords CITRATE SYNTHASE
molecule tags Lyase
source organism Thermus thermophilus
total genus 139
structure length 374
sequence length 374
ec nomenclature ec 4.1.3.7: Transferred entry: 2.3.3.1.
pdb deposition date 2001-03-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00285 Citrate_synt Citrate synthase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.230.10 Mainly Alpha Orthogonal Bundle Cytochrome p450-Terp; domain 2 Cytochrome P450-Terp, domain 2 1iomA02
1.10.580.10 Mainly Alpha Orthogonal Bundle Citrate Synthase; domain 1 Citrate Synthase, domain 1 1iomA01
4G6BA 1AJ8A 4YBOA 2IFCA 6CSCA 1A59A 4TVMA 1VGMA 1AMZA 4CSCA 1CSIA 3TQGA 2R9EA 4CTSA 2IBPA 5CSCA 1NXGA 6CTSA 2CTSA 1VGPA 2H12A 4JAEA 1NXEA 4XGHA 1OWBA 5CSCB 2C6XA 5CTSA 3CSCA 3O8JA 2P2WA 3HWKA 1AL6A 1CTSA 2CSCA 3ENJA 2R26A 4JADA 4JAFA 1CSSA 4JAGA 1CSCA 1CSHA 1O7XA 4E6YA 1CSRA 1IXEA 1IOMA 3MSUA 1OWCA
chains in the Genus database with same CATH superfamily
4G6BA 1AJ8A 4YBOA 2IFCA 6CSCA 1A59A 4TVMA 1VGMA 1AMZA 4CSCA 1CSIA 3TQGA 2R9EA 4CTSA 2IBPA 5CSCA 1NXGA 6CTSA 2CTSA 1VGPA 2H12A 4JAEA 1NXEA 4XGHA 1OWBA 5CSCB 2C6XA 5CTSA 3CSCA 3O8JA 2P2WA 3HWKA 1AL6A 1CTSA 2CSCA 3ENJA 2R26A 4JADA 4JAFA 1CSSA 4JAGA 1CSCA 1CSHA 1O7XA 4E6YA 1CSRA 1IXEA 1IOMA 3MSUA 1OWCA
chains in the Genus database with same CATH topology
4G6BA 1AJ8A 4YBOA 2IFCA 6CSCA 1A59A 4TVMA 1VGMA 1AMZA 4CSCA 1CSIA 3TQGA 2R9EA 4CTSA 2IBPA 5CSCA 1NXGA 6CTSA 2CTSA 1VGPA 2H12A 4JAEA 1NXEA 4XGHA 1OWBA 5CSCB 2C6XA 5CTSA 3CSCA 3O8JA 2P2WA 3HWKA 1AL6A 1CTSA 2CSCA 3ENJA 2R26A 4JADA 4JAFA 1CSSA 4JAGA 1CSCA 1CSHA 1O7XA 4E6YA 1CSRA 1IXEA 1IOMA 3MSUA 1OWCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4G6B A;  1AJ8 A;  4YBO A;  2IFC A;  6CSC A;  1A59 A;  4TVM A;  1VGM A;  1AMZ A;  4CSC A;  1CSI A;  3TQG A;  2R9E A;  4CTS A;  2IBP A;  5CSC A;  1NXG A;  6CTS A;  2CTS A;  1VGP A;  2H12 A;  4JAE A;  1NXE A;  4XGH A;  1OWB A;  5CSC B;  2C6X A;  5CTS A;  3CSC A;  3O8J A;  2P2W A;  3HWK A;  1AL6 A;  1CTS A;  2CSC A;  3ENJ A;  2R26 A;  4JAD A;  4JAF A;  1CSS A;  4JAG A;  1CSC A;  1CSH A;  1O7X A;  4E6Y A;  1CSR A;  1IXE A;  1IOM A;  3MSU A;  1OWC A; 
#chains in the Genus database with same CATH topology
 4G6B A;  1AJ8 A;  4YBO A;  2IFC A;  6CSC A;  1A59 A;  4TVM A;  1VGM A;  1AMZ A;  4CSC A;  1CSI A;  3TQG A;  2R9E A;  4CTS A;  2IBP A;  5CSC A;  1NXG A;  6CTS A;  2CTS A;  1VGP A;  2H12 A;  4JAE A;  1NXE A;  4XGH A;  1OWB A;  5CSC B;  2C6X A;  5CTS A;  3CSC A;  3O8J A;  2P2W A;  3HWK A;  1AL6 A;  1CTS A;  2CSC A;  3ENJ A;  2R26 A;  4JAD A;  4JAF A;  1CSS A;  4JAG A;  1CSC A;  1CSH A;  1O7X A;  4E6Y A;  1CSR A;  1IXE A;  1IOM A;  3MSU A;  1OWC A; 
#chains in the Genus database with same CATH homology
 4G6B A;  1AJ8 A;  4YBO A;  2IFC A;  6CSC A;  1A59 A;  4TVM A;  1VGM A;  1AMZ A;  4CSC A;  1CSI A;  3TQG A;  2R9E A;  4CTS A;  2IBP A;  5CSC A;  1NXG A;  6CTS A;  2CTS A;  1VGP A;  2H12 A;  4JAE A;  1NXE A;  4XGH A;  1OWB A;  5CSC B;  2C6X A;  5CTS A;  3CSC A;  3O8J A;  2P2W A;  3HWK A;  1AL6 A;  1CTS A;  2CSC A;  3ENJ A;  2R26 A;  4JAD A;  4JAF A;  1CSS A;  4JAG A;  1CSC A;  1CSH A;  1O7X A;  4E6Y A;  1CSR A;  1IXE A;  1IOM A;  3MSU A;  1OWC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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