1CSCA

Structure of ternary complexes of citrate synthase with d-and l-malate: mechanistic implications
Total Genus 146
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
146
sequence length
433
structure length
429
Chain Sequence
ASSTNLKDVLAALIPKEQARIKTFRQQHGGTALGQITVDMSYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKGGGGEPLPEGLFWLLVTGQIPTGAQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGILRTKYWEMVYESAMDLIAKLPCVAAKIYRNLYRAGSSIGAIDSKLDWSHNFTNMLGYTDAQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLGWLAQLQKAAGADASLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPGDPMFKLVAQLYKIVPNVLLEQGAAANPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLIAL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title 1.9-A structures of ternary complexes of citrate synthase with D- and L-malate: mechanistic implications.
pubmed doi rcsb
molecule tags Oxo-acid-lyase
source organism Gallus gallus
molecule keywords CITRATE SYNTHASE
total genus 146
structure length 429
sequence length 433
ec nomenclature ec 2.3.3.1: Citrate (Si)-synthase.
pdb deposition date 1990-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00285 Citrate_synt Citrate synthase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.230.10 Mainly Alpha Orthogonal Bundle Cytochrome p450-Terp; domain 2 Cytochrome P450-Terp, domain 2 1cscA02
1.10.580.10 Mainly Alpha Orthogonal Bundle Citrate Synthase; domain 1 Citrate Synthase, domain 1 1cscA01
4JAEA 4CTSA 1VGPA 4YBOA 1NXGA 2IBPA 3MSUA 2C6XA 2P2WA 3CSCA 1OWCA 1CSSA 4G6BA 4XGHA 3ENJA 2CTSA 1IOMA 1CSRA 1VGMA 1IXEA 2H12A 5CTSA 1AMZA 1AJ8A 3TQGA 1O7XA 1CSIA 6CSCA 1OWBA 5CSCA 2R26A 3HWKA 1NXEA 3O8JA 4JADA 4CSCA 1A59A 1CSHA 2R9EA 4E6YA 6CTSA 2CSCA 2IFCA 4JAFA 5CSCB 1AL6A 1CTSA 4JAGA 1CSCA 4TVMA
chains in the Genus database with same CATH superfamily
4JAEA 4CTSA 1VGPA 4YBOA 1NXGA 2IBPA 3MSUA 2C6XA 2P2WA 3CSCA 1OWCA 1CSSA 4G6BA 4XGHA 3ENJA 2CTSA 1IOMA 1CSRA 1VGMA 1IXEA 2H12A 5CTSA 1AMZA 1AJ8A 3TQGA 1O7XA 1CSIA 6CSCA 1OWBA 5CSCA 2R26A 3HWKA 1NXEA 3O8JA 4JADA 4CSCA 1A59A 1CSHA 2R9EA 4E6YA 6CTSA 2CSCA 2IFCA 4JAFA 5CSCB 1AL6A 1CTSA 4JAGA 1CSCA 4TVMA
chains in the Genus database with same CATH topology
4JAEA 4CTSA 1VGPA 4YBOA 1NXGA 2IBPA 3MSUA 2C6XA 2P2WA 3CSCA 1OWCA 1CSSA 4G6BA 4XGHA 3ENJA 2CTSA 1IOMA 1CSRA 1VGMA 1IXEA 2H12A 5CTSA 1AMZA 1AJ8A 3TQGA 1O7XA 1CSIA 6CSCA 1OWBA 5CSCA 2R26A 3HWKA 1NXEA 3O8JA 4JADA 4CSCA 1A59A 1CSHA 2R9EA 4E6YA 6CTSA 2CSCA 2IFCA 4JAFA 5CSCB 1AL6A 1CTSA 4JAGA 1CSCA 4TVMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JAE A;  4CTS A;  1VGP A;  4YBO A;  1NXG A;  2IBP A;  3MSU A;  2C6X A;  2P2W A;  3CSC A;  1OWC A;  1CSS A;  4G6B A;  4XGH A;  3ENJ A;  2CTS A;  1IOM A;  1CSR A;  1VGM A;  1IXE A;  2H12 A;  5CTS A;  1AMZ A;  1AJ8 A;  3TQG A;  1O7X A;  1CSI A;  6CSC A;  1OWB A;  5CSC A;  2R26 A;  3HWK A;  1NXE A;  3O8J A;  4JAD A;  4CSC A;  1A59 A;  1CSH A;  2R9E A;  4E6Y A;  6CTS A;  2CSC A;  2IFC A;  4JAF A;  5CSC B;  1AL6 A;  1CTS A;  4JAG A;  1CSC A;  4TVM A; 
#chains in the Genus database with same CATH topology
 4JAE A;  4CTS A;  1VGP A;  4YBO A;  1NXG A;  2IBP A;  3MSU A;  2C6X A;  2P2W A;  3CSC A;  1OWC A;  1CSS A;  4G6B A;  4XGH A;  3ENJ A;  2CTS A;  1IOM A;  1CSR A;  1VGM A;  1IXE A;  2H12 A;  5CTS A;  1AMZ A;  1AJ8 A;  3TQG A;  1O7X A;  1CSI A;  6CSC A;  1OWB A;  5CSC A;  2R26 A;  3HWK A;  1NXE A;  3O8J A;  4JAD A;  4CSC A;  1A59 A;  1CSH A;  2R9E A;  4E6Y A;  6CTS A;  2CSC A;  2IFC A;  4JAF A;  5CSC B;  1AL6 A;  1CTS A;  4JAG A;  1CSC A;  4TVM A; 
#chains in the Genus database with same CATH homology
 4JAE A;  4CTS A;  1VGP A;  4YBO A;  1NXG A;  2IBP A;  3MSU A;  2C6X A;  2P2W A;  3CSC A;  1OWC A;  1CSS A;  4G6B A;  4XGH A;  3ENJ A;  2CTS A;  1IOM A;  1CSR A;  1VGM A;  1IXE A;  2H12 A;  5CTS A;  1AMZ A;  1AJ8 A;  3TQG A;  1O7X A;  1CSI A;  6CSC A;  1OWB A;  5CSC A;  2R26 A;  3HWK A;  1NXE A;  3O8J A;  4JAD A;  4CSC A;  1A59 A;  1CSH A;  2R9E A;  4E6Y A;  6CTS A;  2CSC A;  2IFC A;  4JAF A;  5CSC B;  1AL6 A;  1CTS A;  4JAG A;  1CSC A;  4TVM A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...