1IXEA

Crystal structure of citrate synthase from thermus thermophilus hb8
Total Genus 133
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
133
sequence length
374
structure length
371
Chain Sequence
VARGLEGVLFTESRMCYIDGQQGKLYYYGIPIQELAEKSSFEETTFLLLHGRLPRRQELEEFSAALARRRALPAHLLESFKRYPVSAHPMSFLRTAVSEFGMLDPTEGDISREALYEKGLDLIAKFATIVAANKRLKEGKEPIPPREDLSHAANFLYMANGVEPSPEQARLMDAALILHAEHGFNASTFTAIAAFSTETDLYSAITAAVASLKGPRHGGANEAVMRMIQEIGTPERAREWVREKLAKKERIMGMGHRVYKAFDPRAGVLEKLARLVAEHSKEYQILKIVEEEAGKVLNPRGIYPNVDFYSGVVYSDLGFSLEFFTPIFAVARISGWVGHILEYQELDNRLLRPGAKYVGELDVPYVPLEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural comparison between the open and closed forms of citrate synthase from Thermus thermophilus HB8
doi rcsb
molecule keywords citrate synthase
molecule tags Lyase
source organism Thermus thermophilus
total genus 133
structure length 371
sequence length 374
chains with identical sequence B, C, D
ec nomenclature ec 4.1.3.7: Transferred entry: 2.3.3.1.
pdb deposition date 2002-06-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00285 Citrate_synt Citrate synthase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.230.10 Mainly Alpha Orthogonal Bundle Cytochrome p450-Terp; domain 2 Cytochrome P450-Terp, domain 2 1ixeA02
1.10.580.10 Mainly Alpha Orthogonal Bundle Citrate Synthase; domain 1 Citrate Synthase, domain 1 1ixeA01
1A59A 1AL6A 4CTSA 4TVMA 1CSHA 4XGHA 3O8JA 2R26A 3CSCA 2CTSA 3ENJA 4JADA 1NXEA 4JAEA 2P2WA 4CSCA 1IOMA 1CSSA 1CTSA 1OWBA 6CTSA 1CSCA 1CSIA 4E6YA 4G6BA 1AJ8A 1NXGA 4JAGA 2C6XA 5CSCA 2H12A 1VGMA 1O7XA 5CSCB 5CTSA 1OWCA 6CSCA 2IBPA 3HWKA 4JAFA 1VGPA 2IFCA 1CSRA 3MSUA 4YBOA 1IXEA 3TQGA 2R9EA 1AMZA 2CSCA
chains in the Genus database with same CATH superfamily
1A59A 1AL6A 4CTSA 4TVMA 1CSHA 4XGHA 3O8JA 2R26A 3CSCA 2CTSA 3ENJA 4JADA 1NXEA 4JAEA 2P2WA 4CSCA 1IOMA 1CSSA 1CTSA 1OWBA 6CTSA 1CSCA 1CSIA 4E6YA 4G6BA 1AJ8A 1NXGA 4JAGA 2C6XA 5CSCA 2H12A 1VGMA 1O7XA 5CSCB 5CTSA 1OWCA 6CSCA 2IBPA 3HWKA 4JAFA 1VGPA 2IFCA 1CSRA 3MSUA 4YBOA 1IXEA 3TQGA 2R9EA 1AMZA 2CSCA
chains in the Genus database with same CATH topology
1A59A 1AL6A 4CTSA 4TVMA 1CSHA 4XGHA 3O8JA 2R26A 3CSCA 2CTSA 3ENJA 4JADA 1NXEA 4JAEA 2P2WA 4CSCA 1IOMA 1CSSA 1CTSA 1OWBA 6CTSA 1CSCA 1CSIA 4E6YA 4G6BA 1AJ8A 1NXGA 4JAGA 2C6XA 5CSCA 2H12A 1VGMA 1O7XA 5CSCB 5CTSA 1OWCA 6CSCA 2IBPA 3HWKA 4JAFA 1VGPA 2IFCA 1CSRA 3MSUA 4YBOA 1IXEA 3TQGA 2R9EA 1AMZA 2CSCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A59 A;  1AL6 A;  4CTS A;  4TVM A;  1CSH A;  4XGH A;  3O8J A;  2R26 A;  3CSC A;  2CTS A;  3ENJ A;  4JAD A;  1NXE A;  4JAE A;  2P2W A;  4CSC A;  1IOM A;  1CSS A;  1CTS A;  1OWB A;  6CTS A;  1CSC A;  1CSI A;  4E6Y A;  4G6B A;  1AJ8 A;  1NXG A;  4JAG A;  2C6X A;  5CSC A;  2H12 A;  1VGM A;  1O7X A;  5CSC B;  5CTS A;  1OWC A;  6CSC A;  2IBP A;  3HWK A;  4JAF A;  1VGP A;  2IFC A;  1CSR A;  3MSU A;  4YBO A;  1IXE A;  3TQG A;  2R9E A;  1AMZ A;  2CSC A; 
#chains in the Genus database with same CATH topology
 1A59 A;  1AL6 A;  4CTS A;  4TVM A;  1CSH A;  4XGH A;  3O8J A;  2R26 A;  3CSC A;  2CTS A;  3ENJ A;  4JAD A;  1NXE A;  4JAE A;  2P2W A;  4CSC A;  1IOM A;  1CSS A;  1CTS A;  1OWB A;  6CTS A;  1CSC A;  1CSI A;  4E6Y A;  4G6B A;  1AJ8 A;  1NXG A;  4JAG A;  2C6X A;  5CSC A;  2H12 A;  1VGM A;  1O7X A;  5CSC B;  5CTS A;  1OWC A;  6CSC A;  2IBP A;  3HWK A;  4JAF A;  1VGP A;  2IFC A;  1CSR A;  3MSU A;  4YBO A;  1IXE A;  3TQG A;  2R9E A;  1AMZ A;  2CSC A; 
#chains in the Genus database with same CATH homology
 1A59 A;  1AL6 A;  4CTS A;  4TVM A;  1CSH A;  4XGH A;  3O8J A;  2R26 A;  3CSC A;  2CTS A;  3ENJ A;  4JAD A;  1NXE A;  4JAE A;  2P2W A;  4CSC A;  1IOM A;  1CSS A;  1CTS A;  1OWB A;  6CTS A;  1CSC A;  1CSI A;  4E6Y A;  4G6B A;  1AJ8 A;  1NXG A;  4JAG A;  2C6X A;  5CSC A;  2H12 A;  1VGM A;  1O7X A;  5CSC B;  5CTS A;  1OWC A;  6CSC A;  2IBP A;  3HWK A;  4JAF A;  1VGP A;  2IFC A;  1CSR A;  3MSU A;  4YBO A;  1IXE A;  3TQG A;  2R9E A;  1AMZ A;  2CSC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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