1CSCA

Structure of ternary complexes of citrate synthase with d-and l-malate: mechanistic implications
Total Genus 146
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
146
sequence length
433
structure length
429
Chain Sequence
ASSTNLKDVLAALIPKEQARIKTFRQQHGGTALGQITVDMSYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKGGGGEPLPEGLFWLLVTGQIPTGAQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGILRTKYWEMVYESAMDLIAKLPCVAAKIYRNLYRAGSSIGAIDSKLDWSHNFTNMLGYTDAQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLGWLAQLQKAAGADASLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPGDPMFKLVAQLYKIVPNVLLEQGAAANPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLIAL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title 1.9-A structures of ternary complexes of citrate synthase with D- and L-malate: mechanistic implications.
pubmed doi rcsb
molecule tags Oxo-acid-lyase
source organism Gallus gallus
molecule keywords CITRATE SYNTHASE
total genus 146
structure length 429
sequence length 433
ec nomenclature ec 2.3.3.1: Citrate (Si)-synthase.
pdb deposition date 1990-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00285 Citrate_synt Citrate synthase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.230.10 Mainly Alpha Orthogonal Bundle Cytochrome p450-Terp; domain 2 Cytochrome P450-Terp, domain 2 1cscA02
1.10.580.10 Mainly Alpha Orthogonal Bundle Citrate Synthase; domain 1 Citrate Synthase, domain 1 1cscA01
5CSCB 2IFCA 1NXEA 1CSHA 3HWKA 2R26A 1A59A 4E6YA 1IOMA 1VGPA 4YBOA 6CSCA 1CSCA 4JAFA 4JAGA 2CTSA 5CSCA 4G6BA 4JADA 4XGHA 1IXEA 1O7XA 1OWCA 2C6XA 4JAEA 1VGMA 5CTSA 4CTSA 2R9EA 3CSCA 2IBPA 3TQGA 4CSCA 2P2WA 1AMZA 1CSSA 3ENJA 1CSIA 1OWBA 1CTSA 1NXGA 2H12A 6CTSA 1AL6A 1CSRA 4TVMA 3O8JA 2CSCA 3MSUA 1AJ8A
chains in the Genus database with same CATH superfamily
5CSCB 2IFCA 1NXEA 1CSHA 3HWKA 2R26A 1A59A 4E6YA 1IOMA 1VGPA 4YBOA 6CSCA 1CSCA 4JAFA 4JAGA 2CTSA 4XGHA 4G6BA 4JADA 5CSCA 1IXEA 1O7XA 1OWCA 2C6XA 4JAEA 1VGMA 5CTSA 4CTSA 2R9EA 3CSCA 2IBPA 3TQGA 4CSCA 2P2WA 1AMZA 1CSSA 3ENJA 1CSIA 1OWBA 1CTSA 1NXGA 2H12A 6CTSA 1AL6A 1CSRA 4TVMA 3O8JA 2CSCA 3MSUA 1AJ8A
chains in the Genus database with same CATH topology
5CSCB 2IFCA 1NXEA 1CSHA 3HWKA 2R26A 1A59A 4E6YA 1IOMA 1VGPA 4YBOA 6CSCA 1CSCA 4JAFA 4JAGA 2CTSA 5CSCA 4G6BA 4JADA 4XGHA 1IXEA 1O7XA 1OWCA 2C6XA 4JAEA 1VGMA 5CTSA 4CTSA 2R9EA 3CSCA 2IBPA 3TQGA 4CSCA 2P2WA 1AMZA 1CSSA 3ENJA 1CSIA 1OWBA 1CTSA 1NXGA 2H12A 6CTSA 1AL6A 1CSRA 4TVMA 3O8JA 2CSCA 3MSUA 1AJ8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CSC B;  2IFC A;  1NXE A;  1CSH A;  3HWK A;  2R26 A;  1A59 A;  4E6Y A;  1IOM A;  1VGP A;  4YBO A;  6CSC A;  1CSC A;  4JAF A;  4JAG A;  2CTS A;  5CSC A;  4G6B A;  4JAD A;  4XGH A;  1IXE A;  1O7X A;  1OWC A;  2C6X A;  4JAE A;  1VGM A;  5CTS A;  4CTS A;  2R9E A;  3CSC A;  2IBP A;  3TQG A;  4CSC A;  2P2W A;  1AMZ A;  1CSS A;  3ENJ A;  1CSI A;  1OWB A;  1CTS A;  1NXG A;  2H12 A;  6CTS A;  1AL6 A;  1CSR A;  4TVM A;  3O8J A;  2CSC A;  3MSU A;  1AJ8 A; 
#chains in the Genus database with same CATH topology
 5CSC B;  2IFC A;  1NXE A;  1CSH A;  3HWK A;  2R26 A;  1A59 A;  4E6Y A;  1IOM A;  1VGP A;  4YBO A;  6CSC A;  1CSC A;  4JAF A;  4JAG A;  2CTS A;  4XGH A;  4G6B A;  4JAD A;  5CSC A;  1IXE A;  1O7X A;  1OWC A;  2C6X A;  4JAE A;  1VGM A;  5CTS A;  4CTS A;  2R9E A;  3CSC A;  2IBP A;  3TQG A;  4CSC A;  2P2W A;  1AMZ A;  1CSS A;  3ENJ A;  1CSI A;  1OWB A;  1CTS A;  1NXG A;  2H12 A;  6CTS A;  1AL6 A;  1CSR A;  4TVM A;  3O8J A;  2CSC A;  3MSU A;  1AJ8 A; 
#chains in the Genus database with same CATH homology
 5CSC B;  2IFC A;  1NXE A;  1CSH A;  3HWK A;  2R26 A;  1A59 A;  4E6Y A;  1IOM A;  1VGP A;  4YBO A;  6CSC A;  1CSC A;  4JAF A;  4JAG A;  2CTS A;  5CSC A;  4G6B A;  4JAD A;  4XGH A;  1IXE A;  1O7X A;  1OWC A;  2C6X A;  4JAE A;  1VGM A;  5CTS A;  4CTS A;  2R9E A;  3CSC A;  2IBP A;  3TQG A;  4CSC A;  2P2W A;  1AMZ A;  1CSS A;  3ENJ A;  1CSI A;  1OWB A;  1CTS A;  1NXG A;  2H12 A;  6CTS A;  1AL6 A;  1CSR A;  4TVM A;  3O8J A;  2CSC A;  3MSU A;  1AJ8 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...