1CSHA

A very short hydrogen bond provides only moderate stabilization of an enzyme: inhibitor complex of citrate synthase
Total Genus 164
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
164
sequence length
435
structure length
435
Chain Sequence
STNLKDVLASLIPKEQARIKTFRQQHGNTAVGQITVDMSYGGMRGMKGLIYETSVLDPDEGIRFRGFSIPECQKLLPKAGGGEEPLPEGLFWLLVTGQIPTPEQVSWVSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGINRTKYWEFVYEDAMDLIAKLPCVAAKIYRNLYRAGSSIGAIDSKLDWSHNFTNMLGYTDPQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLLWLSQLQKDLGADASDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPSDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTAGLEKLSAGG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A very short hydrogen bond provides only moderate stabilization of an enzyme-inhibitor complex of citrate synthase.
pubmed doi rcsb
molecule tags Lyase(oxo-acid)
source organism Gallus gallus
molecule keywords CITRATE SYNTHASE
total genus 164
structure length 435
sequence length 435
ec nomenclature ec 2.3.3.1: Citrate (Si)-synthase.
pdb deposition date 1994-03-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00285 Citrate_synt Citrate synthase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.230.10 Mainly Alpha Orthogonal Bundle Cytochrome p450-Terp; domain 2 Cytochrome P450-Terp, domain 2 1cshA02
1.10.580.10 Mainly Alpha Orthogonal Bundle Citrate Synthase; domain 1 Citrate Synthase, domain 1 1cshA01
4YBOA 1AMZA 3TQGA 2IFCA 1CSRA 1A59A 2CSCA 1CSHA 2R26A 5CSCB 2CTSA 4XGHA 1CSCA 1NXEA 4JADA 3ENJA 1AJ8A 3O8JA 4CTSA 1VGPA 2H12A 2IBPA 1AL6A 2P2WA 5CTSA 6CSCA 4JAFA 5CSCA 1IOMA 6CTSA 4G6BA 1IXEA 1OWCA 4JAEA 1CSSA 3MSUA 1O7XA 3CSCA 2R9EA 4TVMA 1VGMA 1CSIA 2C6XA 1NXGA 1CTSA 3HWKA 4CSCA 1OWBA 4JAGA 4E6YA
chains in the Genus database with same CATH superfamily
4YBOA 1AMZA 3TQGA 2IFCA 1CSRA 1A59A 2CSCA 1CSHA 2R26A 5CSCB 2CTSA 4XGHA 1CSCA 1NXEA 4JADA 3ENJA 1AJ8A 3O8JA 4CTSA 1VGPA 2H12A 2IBPA 1AL6A 2P2WA 5CTSA 6CSCA 4JAFA 5CSCA 1IOMA 6CTSA 4G6BA 1IXEA 1OWCA 4JAEA 1CSSA 3MSUA 1O7XA 3CSCA 2R9EA 4TVMA 1VGMA 1CSIA 2C6XA 1NXGA 1CTSA 3HWKA 4CSCA 1OWBA 4JAGA 4E6YA
chains in the Genus database with same CATH topology
4YBOA 1AMZA 3TQGA 2IFCA 1CSRA 1A59A 2CSCA 1CSHA 2R26A 5CSCB 2CTSA 4XGHA 1CSCA 1NXEA 4JADA 3ENJA 1AJ8A 3O8JA 4CTSA 1VGPA 2H12A 2IBPA 1AL6A 2P2WA 5CTSA 6CSCA 4JAFA 5CSCA 1IOMA 6CTSA 4G6BA 1IXEA 1OWCA 4JAEA 1CSSA 3MSUA 1O7XA 3CSCA 2R9EA 4TVMA 1VGMA 1CSIA 2C6XA 1NXGA 1CTSA 3HWKA 4CSCA 1OWBA 4JAGA 4E6YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YBO A;  1AMZ A;  3TQG A;  2IFC A;  1CSR A;  1A59 A;  2CSC A;  1CSH A;  2R26 A;  5CSC B;  2CTS A;  4XGH A;  1CSC A;  1NXE A;  4JAD A;  3ENJ A;  1AJ8 A;  3O8J A;  4CTS A;  1VGP A;  2H12 A;  2IBP A;  1AL6 A;  2P2W A;  5CTS A;  6CSC A;  4JAF A;  5CSC A;  1IOM A;  6CTS A;  4G6B A;  1IXE A;  1OWC A;  4JAE A;  1CSS A;  3MSU A;  1O7X A;  3CSC A;  2R9E A;  4TVM A;  1VGM A;  1CSI A;  2C6X A;  1NXG A;  1CTS A;  3HWK A;  4CSC A;  1OWB A;  4JAG A;  4E6Y A; 
#chains in the Genus database with same CATH topology
 4YBO A;  1AMZ A;  3TQG A;  2IFC A;  1CSR A;  1A59 A;  2CSC A;  1CSH A;  2R26 A;  5CSC B;  2CTS A;  4XGH A;  1CSC A;  1NXE A;  4JAD A;  3ENJ A;  1AJ8 A;  3O8J A;  4CTS A;  1VGP A;  2H12 A;  2IBP A;  1AL6 A;  2P2W A;  5CTS A;  6CSC A;  4JAF A;  5CSC A;  1IOM A;  6CTS A;  4G6B A;  1IXE A;  1OWC A;  4JAE A;  1CSS A;  3MSU A;  1O7X A;  3CSC A;  2R9E A;  4TVM A;  1VGM A;  1CSI A;  2C6X A;  1NXG A;  1CTS A;  3HWK A;  4CSC A;  1OWB A;  4JAG A;  4E6Y A; 
#chains in the Genus database with same CATH homology
 4YBO A;  1AMZ A;  3TQG A;  2IFC A;  1CSR A;  1A59 A;  2CSC A;  1CSH A;  2R26 A;  5CSC B;  2CTS A;  4XGH A;  1CSC A;  1NXE A;  4JAD A;  3ENJ A;  1AJ8 A;  3O8J A;  4CTS A;  1VGP A;  2H12 A;  2IBP A;  1AL6 A;  2P2W A;  5CTS A;  6CSC A;  4JAF A;  5CSC A;  1IOM A;  6CTS A;  4G6B A;  1IXE A;  1OWC A;  4JAE A;  1CSS A;  3MSU A;  1O7X A;  3CSC A;  2R9E A;  4TVM A;  1VGM A;  1CSI A;  2C6X A;  1NXG A;  1CTS A;  3HWK A;  4CSC A;  1OWB A;  4JAG A;  4E6Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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