1CTSA

Crystallographic refinement and atomic models of two different forms of citrate synthase at 2.7 and 1.7 angstroms resolution
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
437
structure length
437
Chain Sequence
ASSTNLKDILADLIPKEQARIKTFRQQHGNTVVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGYSIPECQKMLPKAKGGEEPLPEGLFWLLVTGQIPTEEQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGIHRTKYWELIYEDCMDLIAKLPCVAAKIYRNLYREGSSIGAIDSKLDWSHNFTNMLGYTDAQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPHDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLIKLVDSK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic refinement and atomic models of two different forms of citrate synthase at 2.7 and 1.7 A resolution.
pubmed doi rcsb
molecule tags Oxo-acid-lyase
source organism Sus scrofa
molecule keywords CITRATE SYNTHASE
total genus 132
structure length 437
sequence length 437
ec nomenclature ec 2.3.3.1: Citrate (Si)-synthase.
pdb deposition date 1984-01-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00285 Citrate_synt Citrate synthase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.230.10 Mainly Alpha Orthogonal Bundle Cytochrome p450-Terp; domain 2 Cytochrome P450-Terp, domain 2 1ctsA02
1.10.580.10 Mainly Alpha Orthogonal Bundle Citrate Synthase; domain 1 Citrate Synthase, domain 1 1ctsA01
2P2WA 4G6BA 1AL6A 1AMZA 1O7XA 6CSCA 4E6YA 3CSCA 1OWCA 4YBOA 2IBPA 1CSHA 3MSUA 4CSCA 1CSRA 1AJ8A 2IFCA 4CTSA 1CSCA 3O8JA 4JAEA 4JAGA 2C6XA 4XGHA 3ENJA 4TVMA 5CSCA 1NXEA 1VGPA 1CTSA 1OWBA 2R26A 2CSCA 6CTSA 4JADA 5CSCB 1CSIA 1CSSA 1VGMA 3HWKA 1NXGA 2R9EA 3TQGA 2CTSA 5CTSA 1IXEA 1IOMA 4JAFA 2H12A 1A59A
chains in the Genus database with same CATH superfamily
2P2WA 4G6BA 1AL6A 1AMZA 1O7XA 6CSCA 4E6YA 3CSCA 1OWCA 4YBOA 2IBPA 1CSHA 3MSUA 4CSCA 1CSRA 1AJ8A 2IFCA 4CTSA 1CSCA 3O8JA 4JAEA 4JAGA 2C6XA 4XGHA 3ENJA 4TVMA 5CSCA 1NXEA 1VGPA 1CTSA 1OWBA 2R26A 2CSCA 6CTSA 4JADA 5CSCB 1CSIA 1CSSA 1VGMA 3HWKA 1NXGA 2R9EA 3TQGA 2CTSA 5CTSA 1IXEA 1IOMA 4JAFA 2H12A 1A59A
chains in the Genus database with same CATH topology
2P2WA 4G6BA 1AL6A 1AMZA 1O7XA 6CSCA 4E6YA 3CSCA 1OWCA 4YBOA 2IBPA 1CSHA 3MSUA 4CSCA 1CSRA 1AJ8A 2IFCA 4CTSA 1CSCA 3O8JA 4JAEA 4JAGA 2C6XA 4XGHA 3ENJA 4TVMA 5CSCA 1NXEA 1VGPA 1CTSA 1OWBA 2R26A 2CSCA 6CTSA 4JADA 5CSCB 1CSIA 1CSSA 1VGMA 3HWKA 1NXGA 2R9EA 3TQGA 2CTSA 5CTSA 1IXEA 1IOMA 4JAFA 2H12A 1A59A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2P2W A;  4G6B A;  1AL6 A;  1AMZ A;  1O7X A;  6CSC A;  4E6Y A;  3CSC A;  1OWC A;  4YBO A;  2IBP A;  1CSH A;  3MSU A;  4CSC A;  1CSR A;  1AJ8 A;  2IFC A;  4CTS A;  1CSC A;  3O8J A;  4JAE A;  4JAG A;  2C6X A;  4XGH A;  3ENJ A;  4TVM A;  5CSC A;  1NXE A;  1VGP A;  1CTS A;  1OWB A;  2R26 A;  2CSC A;  6CTS A;  4JAD A;  5CSC B;  1CSI A;  1CSS A;  1VGM A;  3HWK A;  1NXG A;  2R9E A;  3TQG A;  2CTS A;  5CTS A;  1IXE A;  1IOM A;  4JAF A;  2H12 A;  1A59 A; 
#chains in the Genus database with same CATH topology
 2P2W A;  4G6B A;  1AL6 A;  1AMZ A;  1O7X A;  6CSC A;  4E6Y A;  3CSC A;  1OWC A;  4YBO A;  2IBP A;  1CSH A;  3MSU A;  4CSC A;  1CSR A;  1AJ8 A;  2IFC A;  4CTS A;  1CSC A;  3O8J A;  4JAE A;  4JAG A;  2C6X A;  4XGH A;  3ENJ A;  4TVM A;  5CSC A;  1NXE A;  1VGP A;  1CTS A;  1OWB A;  2R26 A;  2CSC A;  6CTS A;  4JAD A;  5CSC B;  1CSI A;  1CSS A;  1VGM A;  3HWK A;  1NXG A;  2R9E A;  3TQG A;  2CTS A;  5CTS A;  1IXE A;  1IOM A;  4JAF A;  2H12 A;  1A59 A; 
#chains in the Genus database with same CATH homology
 2P2W A;  4G6B A;  1AL6 A;  1AMZ A;  1O7X A;  6CSC A;  4E6Y A;  3CSC A;  1OWC A;  4YBO A;  2IBP A;  1CSH A;  3MSU A;  4CSC A;  1CSR A;  1AJ8 A;  2IFC A;  4CTS A;  1CSC A;  3O8J A;  4JAE A;  4JAG A;  2C6X A;  4XGH A;  3ENJ A;  4TVM A;  5CSC A;  1NXE A;  1VGP A;  1CTS A;  1OWB A;  2R26 A;  2CSC A;  6CTS A;  4JAD A;  5CSC B;  1CSI A;  1CSS A;  1VGM A;  3HWK A;  1NXG A;  2R9E A;  3TQG A;  2CTS A;  5CTS A;  1IXE A;  1IOM A;  4JAF A;  2H12 A;  1A59 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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