1IOMA

Crystal structure of citrate synthase from thermus thermophilus hb8
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
374
structure length
374
Chain Sequence
VARGLEGVLFTESRMCYIDGQQGKLYYYGIPIQELAEKSSFEETTFLLLHGRLPRRQELEEFSAALARRRALPAHLLESFKRYPVSAHPMSFLRTAVSEFGMLDPTEGDISREALYEKGLDLIAKFATIVAANKRLKEGKEPIPPREDLSHAANFLYMANGVEPSPEQARLMDAALILHAEHGFNASTFTAIAAFSTETDLYSAITAAVASLKGPRHGGANEAVMRMIQEIGTPERAREWVREKLAKKERIMGMGHRVYKAFDPRAGVLEKLARLVAEKHGHSKEYQILKIVEEEAGKVLNPRGIYPNVDFYSGVVYSDLGFSLEFFTPIFAVARISGWVGHILEYQELDNRLLRPGAKYVGELDVPYVPLEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural comparison between the open and closed forms of citrate synthase from Thermus thermophilus HB8
doi rcsb
molecule tags Lyase
source organism Thermus thermophilus
molecule keywords CITRATE SYNTHASE
total genus 139
structure length 374
sequence length 374
ec nomenclature ec 4.1.3.7: Transferred entry: 2.3.3.1.
pdb deposition date 2001-03-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00285 Citrate_synt Citrate synthase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.230.10 Mainly Alpha Orthogonal Bundle Cytochrome p450-Terp; domain 2 Cytochrome P450-Terp, domain 2 1iomA02
1.10.580.10 Mainly Alpha Orthogonal Bundle Citrate Synthase; domain 1 Citrate Synthase, domain 1 1iomA01
2C6XA 2CTSA 1AJ8A 2IFCA 5CSCB 3ENJA 5CTSA 5CSCA 1AL6A 2P2WA 1AMZA 4CTSA 1CSRA 1OWBA 4TVMA 3TQGA 4JAGA 1CSCA 2H12A 3CSCA 3HWKA 4CSCA 1NXGA 1CSHA 2CSCA 2R26A 6CSCA 3O8JA 4YBOA 4JADA 2IBPA 3MSUA 1OWCA 1NXEA 1IXEA 1CSSA 1VGMA 4JAEA 1A59A 1CTSA 4JAFA 6CTSA 1IOMA 1CSIA 1O7XA 4G6BA 4E6YA 4XGHA 2R9EA 1VGPA
chains in the Genus database with same CATH superfamily
2C6XA 2CTSA 1AJ8A 2IFCA 5CSCB 3ENJA 5CTSA 5CSCA 1AL6A 2P2WA 1AMZA 4CTSA 1CSRA 1OWBA 4TVMA 3TQGA 4JAGA 1CSCA 2H12A 3CSCA 3HWKA 4CSCA 1NXGA 1CSHA 2CSCA 2R26A 6CSCA 3O8JA 4YBOA 4JADA 2IBPA 3MSUA 1OWCA 1NXEA 1IXEA 1CSSA 1VGMA 4JAEA 1A59A 1CTSA 4JAFA 6CTSA 1IOMA 1CSIA 1O7XA 4G6BA 4XGHA 4E6YA 2R9EA 1VGPA
chains in the Genus database with same CATH topology
2C6XA 2CTSA 1AJ8A 2IFCA 5CSCB 3ENJA 5CTSA 5CSCA 1AL6A 2P2WA 1AMZA 4CTSA 1CSRA 1OWBA 4TVMA 3TQGA 4JAGA 1CSCA 2H12A 3CSCA 3HWKA 4CSCA 1NXGA 1CSHA 2CSCA 2R26A 6CSCA 3O8JA 4YBOA 4JADA 2IBPA 3MSUA 1OWCA 1NXEA 1IXEA 1CSSA 1VGMA 4JAEA 1A59A 1CTSA 4JAFA 6CTSA 1IOMA 1CSIA 1O7XA 4G6BA 4E6YA 4XGHA 2R9EA 1VGPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2C6X A;  2CTS A;  1AJ8 A;  2IFC A;  5CSC B;  3ENJ A;  5CTS A;  5CSC A;  1AL6 A;  2P2W A;  1AMZ A;  4CTS A;  1CSR A;  1OWB A;  4TVM A;  3TQG A;  4JAG A;  1CSC A;  2H12 A;  3CSC A;  3HWK A;  4CSC A;  1NXG A;  1CSH A;  2CSC A;  2R26 A;  6CSC A;  3O8J A;  4YBO A;  4JAD A;  2IBP A;  3MSU A;  1OWC A;  1NXE A;  1IXE A;  1CSS A;  1VGM A;  4JAE A;  1A59 A;  1CTS A;  4JAF A;  6CTS A;  1IOM A;  1CSI A;  1O7X A;  4G6B A;  4E6Y A;  4XGH A;  2R9E A;  1VGP A; 
#chains in the Genus database with same CATH topology
 2C6X A;  2CTS A;  1AJ8 A;  2IFC A;  5CSC B;  3ENJ A;  5CTS A;  5CSC A;  1AL6 A;  2P2W A;  1AMZ A;  4CTS A;  1CSR A;  1OWB A;  4TVM A;  3TQG A;  4JAG A;  1CSC A;  2H12 A;  3CSC A;  3HWK A;  4CSC A;  1NXG A;  1CSH A;  2CSC A;  2R26 A;  6CSC A;  3O8J A;  4YBO A;  4JAD A;  2IBP A;  3MSU A;  1OWC A;  1NXE A;  1IXE A;  1CSS A;  1VGM A;  4JAE A;  1A59 A;  1CTS A;  4JAF A;  6CTS A;  1IOM A;  1CSI A;  1O7X A;  4G6B A;  4XGH A;  4E6Y A;  2R9E A;  1VGP A; 
#chains in the Genus database with same CATH homology
 2C6X A;  2CTS A;  1AJ8 A;  2IFC A;  5CSC B;  3ENJ A;  5CTS A;  5CSC A;  1AL6 A;  2P2W A;  1AMZ A;  4CTS A;  1CSR A;  1OWB A;  4TVM A;  3TQG A;  4JAG A;  1CSC A;  2H12 A;  3CSC A;  3HWK A;  4CSC A;  1NXG A;  1CSH A;  2CSC A;  2R26 A;  6CSC A;  3O8J A;  4YBO A;  4JAD A;  2IBP A;  3MSU A;  1OWC A;  1NXE A;  1IXE A;  1CSS A;  1VGM A;  4JAE A;  1A59 A;  1CTS A;  4JAF A;  6CTS A;  1IOM A;  1CSI A;  1O7X A;  4G6B A;  4E6Y A;  4XGH A;  2R9E A;  1VGP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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