1IXEA

Crystal structure of citrate synthase from thermus thermophilus hb8
Total Genus 133
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
133
sequence length
374
structure length
371
Chain Sequence
VARGLEGVLFTESRMCYIDGQQGKLYYYGIPIQELAEKSSFEETTFLLLHGRLPRRQELEEFSAALARRRALPAHLLESFKRYPVSAHPMSFLRTAVSEFGMLDPTEGDISREALYEKGLDLIAKFATIVAANKRLKEGKEPIPPREDLSHAANFLYMANGVEPSPEQARLMDAALILHAEHGFNASTFTAIAAFSTETDLYSAITAAVASLKGPRHGGANEAVMRMIQEIGTPERAREWVREKLAKKERIMGMGHRVYKAFDPRAGVLEKLARLVAEHSKEYQILKIVEEEAGKVLNPRGIYPNVDFYSGVVYSDLGFSLEFFTPIFAVARISGWVGHILEYQELDNRLLRPGAKYVGELDVPYVPLEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural comparison between the open and closed forms of citrate synthase from Thermus thermophilus HB8
doi rcsb
molecule tags Lyase
source organism Thermus thermophilus
molecule keywords citrate synthase
total genus 133
structure length 371
sequence length 374
chains with identical sequence B, C, D
ec nomenclature ec 4.1.3.7: Transferred entry: 2.3.3.1.
pdb deposition date 2002-06-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00285 Citrate_synt Citrate synthase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.230.10 Mainly Alpha Orthogonal Bundle Cytochrome p450-Terp; domain 2 Cytochrome P450-Terp, domain 2 1ixeA02
1.10.580.10 Mainly Alpha Orthogonal Bundle Citrate Synthase; domain 1 Citrate Synthase, domain 1 1ixeA01
1A59A 2IFCA 4XGHA 4G6BA 1CSHA 1NXEA 2R9EA 1IOMA 1IXEA 4E6YA 2IBPA 3O8JA 4TVMA 4CTSA 1CSIA 1OWBA 4JAFA 5CSCA 3CSCA 1OWCA 5CSCB 1AMZA 1VGPA 1CSSA 4JADA 4JAGA 6CTSA 1CSRA 3ENJA 3TQGA 1AL6A 2R26A 1O7XA 2P2WA 4JAEA 4YBOA 1CTSA 1AJ8A 1VGMA 2C6XA 2CTSA 2CSCA 4CSCA 3HWKA 2H12A 1CSCA 5CTSA 6CSCA 1NXGA 3MSUA
chains in the Genus database with same CATH superfamily
1A59A 2IFCA 4XGHA 4G6BA 1CSHA 1NXEA 2R9EA 1IOMA 1IXEA 4E6YA 2IBPA 3O8JA 4TVMA 4CTSA 1CSIA 1OWBA 4JAFA 5CSCA 3CSCA 1OWCA 5CSCB 1AMZA 1VGPA 1CSSA 4JADA 4JAGA 6CTSA 1CSRA 3ENJA 3TQGA 1AL6A 2R26A 1O7XA 2P2WA 4JAEA 4YBOA 1CTSA 1AJ8A 1VGMA 2C6XA 2CTSA 2CSCA 4CSCA 3HWKA 2H12A 1CSCA 5CTSA 6CSCA 1NXGA 3MSUA
chains in the Genus database with same CATH topology
1A59A 2IFCA 4XGHA 4G6BA 1CSHA 1NXEA 2R9EA 1IOMA 1IXEA 4E6YA 2IBPA 3O8JA 4TVMA 4CTSA 1CSIA 1OWBA 4JAFA 5CSCA 3CSCA 1OWCA 5CSCB 1AMZA 1VGPA 1CSSA 4JADA 4JAGA 6CTSA 1CSRA 3ENJA 3TQGA 1AL6A 2R26A 1O7XA 2P2WA 4JAEA 4YBOA 1CTSA 1AJ8A 1VGMA 2C6XA 2CTSA 2CSCA 4CSCA 3HWKA 2H12A 1CSCA 5CTSA 6CSCA 1NXGA 3MSUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A59 A;  2IFC A;  4XGH A;  4G6B A;  1CSH A;  1NXE A;  2R9E A;  1IOM A;  1IXE A;  4E6Y A;  2IBP A;  3O8J A;  4TVM A;  4CTS A;  1CSI A;  1OWB A;  4JAF A;  5CSC A;  3CSC A;  1OWC A;  5CSC B;  1AMZ A;  1VGP A;  1CSS A;  4JAD A;  4JAG A;  6CTS A;  1CSR A;  3ENJ A;  3TQG A;  1AL6 A;  2R26 A;  1O7X A;  2P2W A;  4JAE A;  4YBO A;  1CTS A;  1AJ8 A;  1VGM A;  2C6X A;  2CTS A;  2CSC A;  4CSC A;  3HWK A;  2H12 A;  1CSC A;  5CTS A;  6CSC A;  1NXG A;  3MSU A; 
#chains in the Genus database with same CATH topology
 1A59 A;  2IFC A;  4XGH A;  4G6B A;  1CSH A;  1NXE A;  2R9E A;  1IOM A;  1IXE A;  4E6Y A;  2IBP A;  3O8J A;  4TVM A;  4CTS A;  1CSI A;  1OWB A;  4JAF A;  5CSC A;  3CSC A;  1OWC A;  5CSC B;  1AMZ A;  1VGP A;  1CSS A;  4JAD A;  4JAG A;  6CTS A;  1CSR A;  3ENJ A;  3TQG A;  1AL6 A;  2R26 A;  1O7X A;  2P2W A;  4JAE A;  4YBO A;  1CTS A;  1AJ8 A;  1VGM A;  2C6X A;  2CTS A;  2CSC A;  4CSC A;  3HWK A;  2H12 A;  1CSC A;  5CTS A;  6CSC A;  1NXG A;  3MSU A; 
#chains in the Genus database with same CATH homology
 1A59 A;  2IFC A;  4XGH A;  4G6B A;  1CSH A;  1NXE A;  2R9E A;  1IOM A;  1IXE A;  4E6Y A;  2IBP A;  3O8J A;  4TVM A;  4CTS A;  1CSI A;  1OWB A;  4JAF A;  5CSC A;  3CSC A;  1OWC A;  5CSC B;  1AMZ A;  1VGP A;  1CSS A;  4JAD A;  4JAG A;  6CTS A;  1CSR A;  3ENJ A;  3TQG A;  1AL6 A;  2R26 A;  1O7X A;  2P2W A;  4JAE A;  4YBO A;  1CTS A;  1AJ8 A;  1VGM A;  2C6X A;  2CTS A;  2CSC A;  4CSC A;  3HWK A;  2H12 A;  1CSC A;  5CTS A;  6CSC A;  1NXG A;  3MSU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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