1IXE | Genus

Total Genus 133

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	133
sequence length	374
structure length	371
Chain Sequence	VARGLEGVLFTESRMCYIDGQQGKLYYYGIPIQELAEKSSFEETTFLLLHGRLPRRQELEEFSAALARRRALPAHLLESFKRYPVSAHPMSFLRTAVSEFGMLDPTEGDISREALYEKGLDLIAKFATIVAANKRLKEGKEPIPPREDLSHAANFLYMANGVEPSPEQARLMDAALILHAEHGFNASTFTAIAAFSTETDLYSAITAAVASLKGPRHGGANEAVMRMIQEIGTPERAREWVREKLAKKERIMGMGHRVYKAFDPRAGVLEKLARLVAEHSKEYQILKIVEEEAGKVLNPRGIYPNVDFYSGVVYSDLGFSLEFFTPIFAVARISGWVGHILEYQELDNRLLRPGAKYVGELDVPYVPLEAR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Lyase
source organism	Thermus thermophilus
publication title	Structural comparison between the open and closed forms of citrate synthase from Thermus thermophilus HB8 doi rcsb
molecule keywords	citrate synthase
total genus	133
structure length	371
sequence length	374
chains with identical sequence	B, C, D
ec nomenclature	ec 4.1.3.7: Transferred entry: 2.3.3.1.
pdb deposition date	2002-06-20

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00285	Citrate_synt	Citrate synthase, C-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.230.10	Mainly Alpha	Orthogonal Bundle	Cytochrome p450-Terp; domain 2	Cytochrome P450-Terp, domain 2	1ixeA02
1.10.580.10	Mainly Alpha	Orthogonal Bundle	Citrate Synthase; domain 1	Citrate Synthase, domain 1	1ixeA01

2CSCA 3ENJA 1IXEA 6CTSA 1VGPA 4E6YA 4JAGA 4TVMA 1CTSA 4YBOA 4XGHA 1AMZA 1O7XA 1OWCA 4JAEA 5CSCB 3O8JA 3CSCA 2P2WA 1NXGA 3HWKA 1IOMA 2R9EA 1VGMA 1OWBA 2IBPA 4JAFA 1A59A 6CSCA 1CSRA 1CSIA 1AL6A 1NXEA 5CSCA 3MSUA 2IFCA 2H12A 1CSCA 4JADA 5CTSA 2CTSA 2R26A 1AJ8A 1CSHA 2C6XA 4G6BA 4CSCA 3TQGA 4CTSA 1CSSA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 2CSC A;  3ENJ A;  1IXE A;  6CTS A;  1VGP A;  4E6Y A;  4JAG A;  4TVM A;  1CTS A;  4YBO A;  4XGH A;  1AMZ A;  1O7X A;  1OWC A;  4JAE A;  5CSC B;  3O8J A;  3CSC A;  2P2W A;  1NXG A;  3HWK A;  1IOM A;  2R9E A;  1VGM A;  1OWB A;  2IBP A;  4JAF A;  1A59 A;  6CSC A;  1CSR A;  1CSI A;  1AL6 A;  1NXE A;  5CSC A;  3MSU A;  2IFC A;  2H12 A;  1CSC A;  4JAD A;  5CTS A;  2CTS A;  2R26 A;  1AJ8 A;  1CSH A;  2C6X A;  4G6B A;  4CSC A;  3TQG A;  4CTS A;  1CSS A; 
#chains in the Genus database with same CATH topology
 2CSC A;  3ENJ A;  1IXE A;  6CTS A;  1VGP A;  4E6Y A;  4JAG A;  4TVM A;  1CTS A;  4YBO A;  4XGH A;  1AMZ A;  1O7X A;  1OWC A;  4JAE A;  5CSC B;  3O8J A;  3CSC A;  2P2W A;  1NXG A;  3HWK A;  1IOM A;  2R9E A;  1VGM A;  1OWB A;  2IBP A;  4JAF A;  1A59 A;  6CSC A;  1CSR A;  1CSI A;  1AL6 A;  1NXE A;  5CSC A;  3MSU A;  2IFC A;  2H12 A;  1CSC A;  4JAD A;  5CTS A;  2CTS A;  2R26 A;  1AJ8 A;  1CSH A;  2C6X A;  4G6B A;  4CSC A;  3TQG A;  4CTS A;  1CSS A; 
#chains in the Genus database with same CATH homology
 2CSC A;  3ENJ A;  1IXE A;  6CTS A;  1VGP A;  4E6Y A;  4JAG A;  4TVM A;  1CTS A;  4YBO A;  4XGH A;  1AMZ A;  1O7X A;  1OWC A;  4JAE A;  5CSC B;  3O8J A;  3CSC A;  2P2W A;  1NXG A;  3HWK A;  1IOM A;  2R9E A;  1VGM A;  1OWB A;  2IBP A;  4JAF A;  1A59 A;  6CSC A;  1CSR A;  1CSI A;  1AL6 A;  1NXE A;  5CSC A;  3MSU A;  2IFC A;  2H12 A;  1CSC A;  4JAD A;  5CTS A;  2CTS A;  2R26 A;  1AJ8 A;  1CSH A;  2C6X A;  4G6B A;  4CSC A;  3TQG A;  4CTS A;  1CSS A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1IXEA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations