1L6EA

Solution structure of the docking and dimerization domain of protein kinase a ii-alpha (riialpha d/d). alternatively called the n-terminal dimerization domain of the regulatory subunit of protein kinase a.
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
46
structure length
46
Chain Sequence
HMGHIQIPPGLTELLQGYTVEVLRQQPPDLVDFAVEYFTRLREARR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Electrostatic properties of the structure of the docking and dimerization domain of protein kinase A IIalpha
pubmed doi rcsb
molecule keywords cAMP-dependent protein kinase Type II-alpha regulatory chain
molecule tags Transferase
source organism Mus musculus
total genus 11
structure length 46
sequence length 46
chains with identical sequence B
ec nomenclature ec 2.7.1.37: Transferred entry: 2.7.11.1, 2.7.11.8, 2.7.11.9, 2.7.11.10, 2.7.11.11,
pdb deposition date 2002-03-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02197 RIIa Regulatory subunit of type II PKA R-subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.890.10 Mainly Alpha Up-down Bundle cAMP-dependent Protein Kinase, Chain A cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 1l6eA00
4RTAA 2DRNA 5HVZA 2EZWA 2KYGA 4RIQA 4ZP3A 3G36A 2H9RA 4RT4A 3IM4A 4F9KA 1L6EA 3IM3A 2IZYA 1R2AA
chains in the Genus database with same CATH superfamily
2CB9A 2KYGA 3S4DA 3QFYA 3IM4A 4F9KA 3AFJA 2K9QA 2EZWA 3QDEA 2OUTA 3S4CA 2H9RA 3UFEA 3ACSA 3IM3A 2CBGA 1R2AA 3QFZA 5HVZA 3RRSA 4ZP3A 3PMIA 4RT4A 2IZYA 4RTAA 2KNGA 3GWHA 2DRNA 2CQSA 3S4AA 4RIQA 2RQYA 2I15A 3G36A 3QG0A 3RSYA 2CQTA 3ACTA 1L6EA 3S4BA
chains in the Genus database with same CATH topology
4RTAA 2DRNA 5HVZA 2EZWA 2KYGA 4RIQA 4ZP3A 3G36A 2H9RA 4RT4A 3IM4A 4F9KA 1L6EA 3IM3A 2IZYA 1R2AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RTA A;  2DRN A;  5HVZ A;  2EZW A;  2KYG A;  4RIQ A;  4ZP3 A;  3G36 A;  2H9R A;  4RT4 A;  3IM4 A;  4F9K A;  1L6E A;  3IM3 A;  2IZY A;  1R2A A; 
#chains in the Genus database with same CATH topology
 2CB9 A;  2KYG A;  3S4D A;  3QFY A;  3IM4 A;  4F9K A;  3AFJ A;  2K9Q A;  2EZW A;  3QDE A;  2OUT A;  3S4C A;  2H9R A;  3UFE A;  3ACS A;  3IM3 A;  2CBG A;  1R2A A;  3QFZ A;  5HVZ A;  3RRS A;  4ZP3 A;  3PMI A;  4RT4 A;  2IZY A;  4RTA A;  2KNG A;  3GWH A;  2DRN A;  2CQS A;  3S4A A;  4RIQ A;  2RQY A;  2I15 A;  3G36 A;  3QG0 A;  3RSY A;  2CQT A;  3ACT A;  1L6E A;  3S4B A; 
#chains in the Genus database with same CATH homology
 4RTA A;  2DRN A;  5HVZ A;  2EZW A;  2KYG A;  4RIQ A;  4ZP3 A;  3G36 A;  2H9R A;  4RT4 A;  3IM4 A;  4F9K A;  1L6E A;  3IM3 A;  2IZY A;  1R2A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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