1L6EA

Solution structure of the docking and dimerization domain of protein kinase a ii-alpha (riialpha d/d). alternatively called the n-terminal dimerization domain of the regulatory subunit of protein kinase a.
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
46
structure length
46
Chain Sequence
HMGHIQIPPGLTELLQGYTVEVLRQQPPDLVDFAVEYFTRLREARR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords cAMP-dependent protein kinase Type II-alpha regulatory chain
publication title Electrostatic properties of the structure of the docking and dimerization domain of protein kinase A IIalpha
pubmed doi rcsb
source organism Mus musculus
total genus 11
structure length 46
sequence length 46
chains with identical sequence B
ec nomenclature ec 2.7.1.37: Transferred entry: 2.7.11.1, 2.7.11.8, 2.7.11.9, 2.7.11.10, 2.7.11.11,
pdb deposition date 2002-03-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02197 RIIa Regulatory subunit of type II PKA R-subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.890.10 Mainly Alpha Up-down Bundle cAMP-dependent Protein Kinase, Chain A cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 1l6eA00
2DRNA 4F9KA 4RIQA 2EZWA 3IM4A 3IM3A 1L6EA 3G36A 2H9RA 4ZP3A 2IZYA 5HVZA 1R2AA 2KYGA 4RT4A 4RTAA
chains in the Genus database with same CATH superfamily
4F9KA 3IM4A 3UFEA 1L6EA 2OUTA 3G36A 2IZYA 1R2AA 2KYGA 3RRSA 4RTAA 3IM3A 3ACSA 3QFYA 3AFJA 3S4BA 2CBGA 3S4AA 4RT4A 2K9QA 2DRNA 2EZWA 3ACTA 2KNGA 3S4DA 3S4CA 3RSYA 3PMIA 2H9RA 4ZP3A 5HVZA 2CQTA 2I15A 3QFZA 3QG0A 2CB9A 2RQYA 2CQSA 3GWHA 4RIQA 3QDEA
chains in the Genus database with same CATH topology
2DRNA 4F9KA 4RIQA 2EZWA 3IM4A 3IM3A 1L6EA 3G36A 2H9RA 4ZP3A 2IZYA 5HVZA 1R2AA 2KYGA 4RT4A 4RTAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DRN A;  4F9K A;  4RIQ A;  2EZW A;  3IM4 A;  3IM3 A;  1L6E A;  3G36 A;  2H9R A;  4ZP3 A;  2IZY A;  5HVZ A;  1R2A A;  2KYG A;  4RT4 A;  4RTA A; 
#chains in the Genus database with same CATH topology
 4F9K A;  3IM4 A;  3UFE A;  1L6E A;  2OUT A;  3G36 A;  2IZY A;  1R2A A;  2KYG A;  3RRS A;  4RTA A;  3IM3 A;  3ACS A;  3QFY A;  3AFJ A;  3S4B A;  2CBG A;  3S4A A;  4RT4 A;  2K9Q A;  2DRN A;  2EZW A;  3ACT A;  2KNG A;  3S4D A;  3S4C A;  3RSY A;  3PMI A;  2H9R A;  4ZP3 A;  5HVZ A;  2CQT A;  2I15 A;  3QFZ A;  3QG0 A;  2CB9 A;  2RQY A;  2CQS A;  3GWH A;  4RIQ A;  3QDE A; 
#chains in the Genus database with same CATH homology
 2DRN A;  4F9K A;  4RIQ A;  2EZW A;  3IM4 A;  3IM3 A;  1L6E A;  3G36 A;  2H9R A;  4ZP3 A;  2IZY A;  5HVZ A;  1R2A A;  2KYG A;  4RT4 A;  4RTA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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