1MMIA

E. coli dna polymerase beta subunit
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
366
structure length
366
Chain Sequence
MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Flexibility revealed by the 1.85 A crystal structure of the beta sliding-clamp subunit of Escherichia coli DNA polymerase III.
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords DNA polymerase III, beta chain
total genus 89
structure length 366
sequence length 366
chains with identical sequence B
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2002-09-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
A PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
A PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 1mmiA02
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 1mmiA03
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 1mmiA01
5AGUA 3D1GA 3Q4LA 4PNUA 4PNVA 4TRTA 3RB9A 3BEPA 4TSZA 2POLA 5FRQA 1MMIA 4MJPA 5FVEA 4N99A 3L10A 3P16A 4TR7A 4K3OA 3L0WA 4K3MA 3QSBA 5AGVA 4OVFA 4OVGA 3QSBB 3F1VA 2AWAA 2AVTA 3PWEA 4K74A 4K3KA 4N98A 4K3SA 4N97A 4TR8A 4TR6A 1UNNA 2XURA 1OK7A 4K3RA 1JQLA 4PNWA 4RKIA 3D1EA 4N94A 4N96A 1VPKA 3Q4KA 4OVHA 3L0XA 4S3IA 3T0PA 4N95A 5AH2A 3D1FA 4MJRA 4MJQA 1JQJA 4K3LA 3Q4JA 5AH4A 4K3PA 3PGEB 4N9AA 4K3QA
chains in the Genus database with same CATH superfamily
5AGUA 3D1GA 3Q4LA 4PNUA 4PNVA 4TRTA 3RB9A 3BEPA 4TSZA 2POLA 5FRQA 1MMIA 4MJPA 5FVEA 4N99A 3L10A 3P16A 3L10B 3L0WB 3L0WA 4K3OA 4TR7A 4K3MA 3QSBA 5AGVA 4OVFA 4OVGA 3QSBB 3F1VA 2AWAA 2AVTA 3PWEA 4K74A 4K3KA 4N98A 4K3SA 4N97A 4TR8A 4TR6A 1UNNA 2XURA 1OK7A 4K3RA 1JQLA 4PNWA 4RKIA 3D1EA 4N94A 4N96A 1VPKA 3Q4KA 4OVHA 3L0XA 4S3IA 3T0PA 4N95A 3L0XB 5AH2A 3D1FA 4MJRA 4MJQA 1JQJA 4K3LA 3PGEA 3Q4JA 5AH4A 4K3PA 3PGEB 4N9AA 4K3QA
chains in the Genus database with same CATH topology
5AGUA 3D1GA 3Q4LA 4PNUA 4PNVA 4TRTA 3RB9A 3BEPA 4TSZA 2POLA 5FRQA 1MMIA 4MJPA 5FVEA 4N99A 3L10A 3P16A 4TR7A 4K3OA 3L0WA 4K3MA 3QSBA 5AGVA 4OVFA 4OVGA 3QSBB 3F1VA 2AWAA 2AVTA 3PWEA 4K74A 4K3KA 4N98A 4K3SA 4N97A 4TR8A 4TR6A 1UNNA 2XURA 1OK7A 4K3RA 1JQLA 4PNWA 4RKIA 3D1EA 4N94A 4N96A 1VPKA 3Q4KA 4OVHA 3L0XA 4S3IA 3T0PA 4N95A 5AH2A 3D1FA 4MJRA 4MJQA 1JQJA 4K3LA 3Q4JA 5AH4A 4K3PA 3PGEB 4N9AA 4K3QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5AGU A;  3D1G A;  3Q4L A;  4PNU A;  4PNV A;  4TRT A;  3RB9 A;  3BEP A;  4TSZ A;  2POL A;  5FRQ A;  1MMI A;  4MJP A;  5FVE A;  4N99 A;  3L10 A;  3P16 A;  4TR7 A;  4K3O A;  3L0W A;  4K3M A;  3QSB A;  5AGV A;  4OVF A;  4OVG A;  3QSB B;  3F1V A;  2AWA A;  2AVT A;  3PWE A;  4K74 A;  4K3K A;  4N98 A;  4K3S A;  4N97 A;  4TR8 A;  4TR6 A;  1UNN A;  2XUR A;  1OK7 A;  4K3R A;  1JQL A;  4PNW A;  4RKI A;  3D1E A;  4N94 A;  4N96 A;  1VPK A;  3Q4K A;  4OVH A;  3L0X A;  4S3I A;  3T0P A;  4N95 A;  5AH2 A;  3D1F A;  4MJR A;  4MJQ A;  1JQJ A;  4K3L A;  3Q4J A;  5AH4 A;  4K3P A;  3PGE B;  4N9A A;  4K3Q A; 
#chains in the Genus database with same CATH topology
 5AGU A;  3D1G A;  3Q4L A;  4PNU A;  4PNV A;  4TRT A;  3RB9 A;  3BEP A;  4TSZ A;  2POL A;  5FRQ A;  1MMI A;  4MJP A;  5FVE A;  4N99 A;  3L10 A;  3P16 A;  3L10 B;  3L0W B;  3L0W A;  4K3O A;  4TR7 A;  4K3M A;  3QSB A;  5AGV A;  4OVF A;  4OVG A;  3QSB B;  3F1V A;  2AWA A;  2AVT A;  3PWE A;  4K74 A;  4K3K A;  4N98 A;  4K3S A;  4N97 A;  4TR8 A;  4TR6 A;  1UNN A;  2XUR A;  1OK7 A;  4K3R A;  1JQL A;  4PNW A;  4RKI A;  3D1E A;  4N94 A;  4N96 A;  1VPK A;  3Q4K A;  4OVH A;  3L0X A;  4S3I A;  3T0P A;  4N95 A;  3L0X B;  5AH2 A;  3D1F A;  4MJR A;  4MJQ A;  1JQJ A;  4K3L A;  3PGE A;  3Q4J A;  5AH4 A;  4K3P A;  3PGE B;  4N9A A;  4K3Q A; 
#chains in the Genus database with same CATH homology
 5AGU A;  3D1G A;  3Q4L A;  4PNU A;  4PNV A;  4TRT A;  3RB9 A;  3BEP A;  4TSZ A;  2POL A;  5FRQ A;  1MMI A;  4MJP A;  5FVE A;  4N99 A;  3L10 A;  3P16 A;  4TR7 A;  4K3O A;  3L0W A;  4K3M A;  3QSB A;  5AGV A;  4OVF A;  4OVG A;  3QSB B;  3F1V A;  2AWA A;  2AVT A;  3PWE A;  4K74 A;  4K3K A;  4N98 A;  4K3S A;  4N97 A;  4TR8 A;  4TR6 A;  1UNN A;  2XUR A;  1OK7 A;  4K3R A;  1JQL A;  4PNW A;  4RKI A;  3D1E A;  4N94 A;  4N96 A;  1VPK A;  3Q4K A;  4OVH A;  3L0X A;  4S3I A;  3T0P A;  4N95 A;  5AH2 A;  3D1F A;  4MJR A;  4MJQ A;  1JQJ A;  4K3L A;  3Q4J A;  5AH4 A;  4K3P A;  3PGE B;  4N9A A;  4K3Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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