1MMIA

E. coli dna polymerase beta subunit
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
366
structure length
366
Chain Sequence
MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Flexibility revealed by the 1.85 A crystal structure of the beta sliding-clamp subunit of Escherichia coli DNA polymerase III.
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords DNA polymerase III, beta chain
total genus 89
structure length 366
sequence length 366
chains with identical sequence B
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2002-09-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
A PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
A PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 1mmiA02
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 1mmiA03
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 1mmiA01
5AH2A 5AH4A 3L0WA 4MJRA 3BEPA 1VPKA 2AVTA 4OVFA 5AGVA 4MJPA 3Q4LA 4RKIA 3Q4JA 2AWAA 4N99A 4TR6A 4N97A 4N96A 4PNVA 1JQJA 1OK7A 4N94A 3QSBA 4N98A 4K3OA 4MJQA 4TRTA 5FVEA 4K3QA 4K3LA 3PWEA 2XURA 3L10A 4PNUA 3T0PA 3P16A 1UNNA 4K3RA 4K3KA 2POLA 3PGEB 4K3PA 3D1EA 4K3SA 3QSBB 4S3IA 4TR8A 4K3MA 3F1VA 4K74A 5FRQA 3RB9A 1JQLA 4N9AA 4PNWA 3L0XA 3D1GA 4OVGA 4OVHA 4TR7A 3Q4KA 4TSZA 5AGUA 3D1FA 4N95A 1MMIA
chains in the Genus database with same CATH superfamily
5AH2A 5AH4A 3L0WA 4MJRA 3BEPA 1VPKA 2AVTA 4OVFA 5AGVA 3L0XB 4MJPA 3Q4LA 4RKIA 3Q4JA 2AWAA 4N99A 4TR6A 4N97A 4N96A 4PNVA 1JQJA 1OK7A 4N94A 3L0WB 3PGEA 3QSBA 4K3OA 4MJQA 4N98A 4TRTA 5FVEA 4K3QA 4K3LA 3PWEA 2XURA 3L10A 4PNUA 3T0PA 3P16A 1UNNA 4K3RA 4K3KA 2POLA 3PGEB 4K3PA 3D1EA 4K3SA 3QSBB 4S3IA 3L10B 4K3MA 3F1VA 4K74A 4TR8A 5FRQA 1JQLA 3RB9A 4N9AA 4PNWA 3L0XA 3D1GA 4OVGA 4OVHA 4TR7A 3Q4KA 4TSZA 5AGUA 3D1FA 4N95A 1MMIA
chains in the Genus database with same CATH topology
5AH2A 5AH4A 3L0WA 4MJRA 3BEPA 1VPKA 2AVTA 4OVFA 5AGVA 4MJPA 3Q4LA 4RKIA 3Q4JA 2AWAA 4N99A 4TR6A 4N97A 4N96A 4PNVA 1JQJA 1OK7A 4N94A 3QSBA 4N98A 4K3OA 4MJQA 4TRTA 5FVEA 4K3QA 4K3LA 3PWEA 2XURA 3L10A 4PNUA 3T0PA 3P16A 1UNNA 4K3RA 4K3KA 2POLA 3PGEB 4K3PA 3D1EA 4K3SA 3QSBB 4S3IA 4TR8A 4K3MA 3F1VA 4K74A 5FRQA 3RB9A 1JQLA 4N9AA 4PNWA 3L0XA 3D1GA 4OVGA 4OVHA 4TR7A 3Q4KA 4TSZA 5AGUA 3D1FA 4N95A 1MMIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5AH2 A;  5AH4 A;  3L0W A;  4MJR A;  3BEP A;  1VPK A;  2AVT A;  4OVF A;  5AGV A;  4MJP A;  3Q4L A;  4RKI A;  3Q4J A;  2AWA A;  4N99 A;  4TR6 A;  4N97 A;  4N96 A;  4PNV A;  1JQJ A;  1OK7 A;  4N94 A;  3QSB A;  4N98 A;  4K3O A;  4MJQ A;  4TRT A;  5FVE A;  4K3Q A;  4K3L A;  3PWE A;  2XUR A;  3L10 A;  4PNU A;  3T0P A;  3P16 A;  1UNN A;  4K3R A;  4K3K A;  2POL A;  3PGE B;  4K3P A;  3D1E A;  4K3S A;  3QSB B;  4S3I A;  4TR8 A;  4K3M A;  3F1V A;  4K74 A;  5FRQ A;  3RB9 A;  1JQL A;  4N9A A;  4PNW A;  3L0X A;  3D1G A;  4OVG A;  4OVH A;  4TR7 A;  3Q4K A;  4TSZ A;  5AGU A;  3D1F A;  4N95 A;  1MMI A; 
#chains in the Genus database with same CATH topology
 5AH2 A;  5AH4 A;  3L0W A;  4MJR A;  3BEP A;  1VPK A;  2AVT A;  4OVF A;  5AGV A;  3L0X B;  4MJP A;  3Q4L A;  4RKI A;  3Q4J A;  2AWA A;  4N99 A;  4TR6 A;  4N97 A;  4N96 A;  4PNV A;  1JQJ A;  1OK7 A;  4N94 A;  3L0W B;  3PGE A;  3QSB A;  4K3O A;  4MJQ A;  4N98 A;  4TRT A;  5FVE A;  4K3Q A;  4K3L A;  3PWE A;  2XUR A;  3L10 A;  4PNU A;  3T0P A;  3P16 A;  1UNN A;  4K3R A;  4K3K A;  2POL A;  3PGE B;  4K3P A;  3D1E A;  4K3S A;  3QSB B;  4S3I A;  3L10 B;  4K3M A;  3F1V A;  4K74 A;  4TR8 A;  5FRQ A;  1JQL A;  3RB9 A;  4N9A A;  4PNW A;  3L0X A;  3D1G A;  4OVG A;  4OVH A;  4TR7 A;  3Q4K A;  4TSZ A;  5AGU A;  3D1F A;  4N95 A;  1MMI A; 
#chains in the Genus database with same CATH homology
 5AH2 A;  5AH4 A;  3L0W A;  4MJR A;  3BEP A;  1VPK A;  2AVT A;  4OVF A;  5AGV A;  4MJP A;  3Q4L A;  4RKI A;  3Q4J A;  2AWA A;  4N99 A;  4TR6 A;  4N97 A;  4N96 A;  4PNV A;  1JQJ A;  1OK7 A;  4N94 A;  3QSB A;  4N98 A;  4K3O A;  4MJQ A;  4TRT A;  5FVE A;  4K3Q A;  4K3L A;  3PWE A;  2XUR A;  3L10 A;  4PNU A;  3T0P A;  3P16 A;  1UNN A;  4K3R A;  4K3K A;  2POL A;  3PGE B;  4K3P A;  3D1E A;  4K3S A;  3QSB B;  4S3I A;  4TR8 A;  4K3M A;  3F1V A;  4K74 A;  5FRQ A;  3RB9 A;  1JQL A;  4N9A A;  4PNW A;  3L0X A;  3D1G A;  4OVG A;  4OVH A;  4TR7 A;  3Q4K A;  4TSZ A;  5AGU A;  3D1F A;  4N95 A;  1MMI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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