1PREA

Proaerolysin
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
469
structure length
449
Chain Sequence
EPVYPDQLRLFSLGQGVCGDKYRPVNREEAQSVKSNIVGMMGQWQISGLANGWVIMGPGYNGEIKPGTASNTWCYPTNPVTGEIPTLSALDIPDGDEVDVQWRLVHDSANFIKPTSYLAHYLGYAWVGGNHSQYVGEDMDVTRDGDGWVIRGNNDGGCDGYRCGDKTAIKVSNFAYNLDPDSFKHGDVTQSDRQLVKTVVGWAVNDPQSGYDVTLRYDTATNWSKTNTYGLSEKVTTKNKFKWPLVGETELSIEIAANQSWASQNGGSTTTSLSQSVRPTVPARSKIPVKIELYKADISYPYEFKADVSYDLTLSGFLRWGGNAWYTHPDNRPNWNHTFVIGPYKDKASSIRYQWDKRYIPGEVKWWDWNWTIQQNGLSTMQNNLARVLRPVRAGITGDFSAESQFAGNIEIGAPVPLGLRLEIPLDAQELSGLGFNNVSLSVTPAANQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Aeromonas toxin proaerolysin in its water-soluble and membrane-channel states.
pubmed doi rcsb
molecule keywords PROAEROLYSIN
molecule tags Toxin (hemolytic polypeptide)
source organism Aeromonas hydrophila
total genus 106
structure length 449
sequence length 469
chains with identical sequence B
ec nomenclature
pdb deposition date 1995-09-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01117 Aerolysin Aerolysin toxin
A PF03440 APT Aerolysin/Pertussis toxin (APT) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.15.10 Mainly Beta Beta Complex Proaerolysin; Chain A, domain 3 Proaerolysin, chain A, domain 3 1preA03
3.10.40.10 Alpha Beta Roll Pertussis Toxin; Chain B, domain 1 Aerolysin/Pertussis toxin (APT), N-terminal domain 1preA01
3.30.412.10 Alpha Beta 2-Layer Sandwich Proaerolysin; Chain A, domain 2 Proaerolysin, chain A, domain 2 1preA02
1BCPB 3C0MA 3C0NA 1PTOC 1PRTB 2D42A 1PTOH 1UYJA 3ZJXA 1PREA 1PTOB 1Z52A 1BCPC 1W3AA 3G4OA 1W3FA 1W3GA 3G4NA 1PRTC 3C0OA
chains in the Genus database with same CATH superfamily
1BCPB 3C0MA 3C0NA 1PTOC 1PRTB 2D42A 1PTOH 1UYJA 3ZJXA 1PREA 1PTOB 1Z52A 1BCPC 1W3AA 3G4OA 1W3FA 1W3GA 3G4NA 1PRTC 3C0OA
chains in the Genus database with same CATH topology
1BCPB 3C0MA 3C0NA 1PTOC 1PRTB 2D42A 1PTOH 1UYJA 3ZJXA 1PREA 1PTOB 1Z52A 1BCPC 1W3AA 3G4OA 1W3FA 1W3GA 3G4NA 1PRTC 3C0OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BCP B;  3C0M A;  3C0N A;  1PTO C;  1PRT B;  2D42 A;  1PTO H;  1UYJ A;  3ZJX A;  1PRE A;  1PTO B;  1Z52 A;  1BCP C;  1W3A A;  3G4O A;  1W3F A;  1W3G A;  3G4N A;  1PRT C;  3C0O A; 
#chains in the Genus database with same CATH topology
 1BCP B;  3C0M A;  3C0N A;  1PTO C;  1PRT B;  2D42 A;  1PTO H;  1UYJ A;  3ZJX A;  1PRE A;  1PTO B;  1Z52 A;  1BCP C;  1W3A A;  3G4O A;  1W3F A;  1W3G A;  3G4N A;  1PRT C;  3C0O A; 
#chains in the Genus database with same CATH homology
 1BCP B;  3C0M A;  3C0N A;  1PTO C;  1PRT B;  2D42 A;  1PTO H;  1UYJ A;  3ZJX A;  1PRE A;  1PTO B;  1Z52 A;  1BCP C;  1W3A A;  3G4O A;  1W3F A;  1W3G A;  3G4N A;  1PRT C;  3C0O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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