1R2AA

The molecular basis for protein kinase a anchoring revealed by solution nmr
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
46
structure length
46
Chain Sequence
HMGHIQIPPGLTELLQGYTVEVLRQQPPDLVDFAVEYFTRLREARR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The molecular basis for protein kinase A anchoring revealed by solution NMR.
pubmed doi rcsb
molecule keywords PROTEIN (CAMP-DEPENDENT PROTEIN KINASE TYPE II REGULATORY SU
molecule tags Transferase
source organism Mus musculus
total genus 12
structure length 46
sequence length 46
chains with identical sequence B
ec nomenclature ec 2.7.1.37: Transferred entry: 2.7.11.1, 2.7.11.8, 2.7.11.9, 2.7.11.10, 2.7.11.11,
pdb deposition date 1998-12-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02197 RIIa Regulatory subunit of type II PKA R-subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.890.10 Mainly Alpha Up-down Bundle cAMP-dependent Protein Kinase, Chain A cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 1r2aA00
2H9RA 2IZYA 2KYGA 3IM3A 4RTAA 4RT4A 4F9KA 2EZWA 2DRNA 4ZP3A 1R2AA 5HVZA 1L6EA 4RIQA 3G36A 3IM4A
chains in the Genus database with same CATH superfamily
3RSYA 2CQTA 2I15A 3S4AA 2EZWA 3UFEA 3PMIA 3IM3A 3ACSA 2CB9A 3ACTA 2DRNA 3GWHA 4RIQA 2OUTA 4ZP3A 4F9KA 3S4CA 3QDEA 2H9RA 2KYGA 3S4BA 3QFYA 2RQYA 1R2AA 1L6EA 3G36A 3S4DA 3IM4A 3RRSA 2K9QA 2CBGA 2IZYA 3QFZA 2CQSA 3AFJA 4RTAA 4RT4A 2KNGA 5HVZA 3QG0A
chains in the Genus database with same CATH topology
2H9RA 2IZYA 2KYGA 3IM3A 4RTAA 4RT4A 4F9KA 2EZWA 2DRNA 4ZP3A 1R2AA 5HVZA 1L6EA 4RIQA 3G36A 3IM4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2H9R A;  2IZY A;  2KYG A;  3IM3 A;  4RTA A;  4RT4 A;  4F9K A;  2EZW A;  2DRN A;  4ZP3 A;  1R2A A;  5HVZ A;  1L6E A;  4RIQ A;  3G36 A;  3IM4 A; 
#chains in the Genus database with same CATH topology
 3RSY A;  2CQT A;  2I15 A;  3S4A A;  2EZW A;  3UFE A;  3PMI A;  3IM3 A;  3ACS A;  2CB9 A;  3ACT A;  2DRN A;  3GWH A;  4RIQ A;  2OUT A;  4ZP3 A;  4F9K A;  3S4C A;  3QDE A;  2H9R A;  2KYG A;  3S4B A;  3QFY A;  2RQY A;  1R2A A;  1L6E A;  3G36 A;  3S4D A;  3IM4 A;  3RRS A;  2K9Q A;  2CBG A;  2IZY A;  3QFZ A;  2CQS A;  3AFJ A;  4RTA A;  4RT4 A;  2KNG A;  5HVZ A;  3QG0 A; 
#chains in the Genus database with same CATH homology
 2H9R A;  2IZY A;  2KYG A;  3IM3 A;  4RTA A;  4RT4 A;  4F9K A;  2EZW A;  2DRN A;  4ZP3 A;  1R2A A;  5HVZ A;  1L6E A;  4RIQ A;  3G36 A;  3IM4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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