1WX2A

Crystal structure of the oxy-form of the copper-bound streptomyces castaneoglobisporus tyrosinase complexed with a caddie protein prepared by the addition of hydrogenperoxide
Total Genus 100

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
273
structure length
273
Chain Sequence
TVRKNQATLTADEKRRFVAAVLELKRSGRYDEFVRTHNEFIMSDTDSGERTGHRSPSFLPWHRRFLLDFEQALQSVDSSVTLPYWDWSADRTVRASLWAPDFLGGTGRSTDGRVMDGPFAASTGNWPINVRVDSRTYLRRSLGGSVAELPTRAEVESVLAISAYDLPPYNSASEGFRNHLEGWRGVNLHNRVHVWVGGQMATGVSPNDPVFWLHHAYVDKLWAEWQRRHPDSAYVPTGGTPDVVDLNETMKPWNTVRPADLLDHTAYYTFDAL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYTIV16 (266-269)TI2 (78-81)AH3 (58-77)S1 (3-4)S2 (270-271)AH1 (12-28)TIV8 (125-128)3H5 (206-208)AH2 (30-44)AH7 (210-229)TIV9 (129-132)TI9 (203-206)TI1 (46-49)TIV1 (51-54)TVIa1 (167-170)TI8 (171-174)TVIa2 (251-254)AH5 (177-182)TIV12 (164-167)3H6 (259-261)TVIII2 (262-265)TI3 (87-90)3H2 (97-99)TIV4 (101-104)TI5 (100-103)TIV7 (110-113)TIV6 (109-112)3H3 (122-124)TIV10 (132-135)AH6 (189-197)TII1 (142-145)TIV11 (145-148)AH4 (153-161)TI10 (230-233)TVIII1 (183-186)3H4 (199-202)TI13 (265-268)TI11 (246-249)TIV15 (254-257)TI12 (264-267)TIV2 (88-91)TI4 (93-96)TIV3 (89-92)TIV5 (102-105)TIV13 (185-188)3H1 (7-9)TII2 (241-244)TI6 (118-121)Updating...
connected with : NaN
publication title Crystallographic Evidence That the Dinuclear Copper Center of Tyrosinase Is Flexible during Catalysis
pubmed doi rcsb
molecule tags Oxidoreductase/metal transport
source organism Streptomyces castaneoglobisporus
molecule keywords tyrosinase
total genus 100
structure length 273
sequence length 273
ec nomenclature ec 1.14.18.1: Tyrosinase.
pdb deposition date 2005-01-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00264 Tyrosinase Common central domain of tyrosinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1280.10 Mainly Alpha Orthogonal Bundle di-copper center containing domain from catechol oxidase Di-copper center containing domain from catechol oxidase 1wx2A00
2ZWDA 4Z0ZA 3AWXA 2ZWFA 4J6TA 3WKYA 1OXYA 5CE9A 1WXCA 4J3RA 3HHSA 1BT3A 3NQ1A 3QJOA 3W6WA 3AWWA 4P6RA 3AX0A 2Y9XA 2ZMXA 3GWJA 3AWZA 3AWSA 1HC1A 3W6QA 2Y9WA 4L37B 1WX4A 3NPYA 4J6VA 1BT1A 3AWUA 4OUAA 3NTMA 1LL1A 1WX2A 3WJMB 5I3BA 3AWVA 1HCYA 4Z0YA 1BUGA 4L37A 4P6SA 2ZMYA 3HHSB 1JS8A 3NQ5A 4YZWA 5I3AA 4J6UA 3NQ0A 1LLAA 3WJMA 2ZMZA 4Z10A 4D87A 4P6TA 1WX5A 2P3XA 4HD7A 1BT2A 4J3PA 4J3QA 2AHLA 2ZWGA 1LNLA 2ZWEA 4HD6A 5I38A 1NOLA 4HD4A 4OUAB 2AHKA 3NM8A 3AWYA 3AWTA
chains in the Genus database with same CATH superfamily
2ZWDA 4Z0ZA 3AWXA 2ZWFA 4J6TA 3WKYA 1OXYA 5CE9A 1WXCA 4J3RA 3HHSA 1BT3A 3NQ1A 3QJOA 3W6WA 3AWWA 4P6RA 3AX0A 2Y9XA 2ZMXA 3GWJA 3AWZA 3AWSA 1HC1A 3W6QA 2Y9WA 4L37B 1WX4A 3NPYA 4J6VA 1BT1A 3AWUA 4OUAA 3NTMA 1LL1A 1WX2A 3WJMB 5I3BA 3AWVA 1HCYA 4Z0YA 1BUGA 4L37A 4P6SA 2ZMYA 3HHSB 1JS8A 3NQ5A 4YZWA 5I3AA 4J6UA 3NQ0A 1LLAA 3WJMA 2ZMZA 4Z10A 4D87A 4P6TA 1WX5A 2P3XA 4HD7A 1BT2A 4J3PA 4J3QA 2AHLA 2ZWGA 1LNLA 2ZWEA 4HD6A 5I38A 1NOLA 4HD4A 4OUAB 2AHKA 3NM8A 3AWYA 3AWTA
chains in the Genus database with same CATH topology
2ZWDA 4Z0ZA 3AWXA 2ZWFA 4J6TA 3WKYA 1OXYA 5CE9A 1WXCA 4J3RA 3HHSA 1BT3A 3NQ1A 3QJOA 3W6WA 3AWWA 4P6RA 3AX0A 2Y9XA 2ZMXA 3GWJA 3AWZA 3AWSA 1HC1A 3W6QA 2Y9WA 4L37B 1WX4A 3NPYA 4J6VA 1BT1A 3AWUA 4OUAA 3NTMA 1LL1A 1WX2A 3WJMB 5I3BA 3AWVA 1HCYA 4Z0YA 1BUGA 4L37A 4P6SA 2ZMYA 3HHSB 1JS8A 3NQ5A 4YZWA 5I3AA 4J6UA 3NQ0A 1LLAA 3WJMA 2ZMZA 4Z10A 4D87A 4P6TA 1WX5A 2P3XA 4HD7A 1BT2A 4J3PA 4J3QA 2AHLA 2ZWGA 1LNLA 2ZWEA 4HD6A 5I38A 1NOLA 4HD4A 4OUAB 2AHKA 3NM8A 3AWYA 3AWTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZWD A;  4Z0Z A;  3AWX A;  2ZWF A;  4J6T A;  3WKY A;  1OXY A;  5CE9 A;  1WXC A;  4J3R A;  3HHS A;  1BT3 A;  3NQ1 A;  3QJO A;  3W6W A;  3AWW A;  4P6R A;  3AX0 A;  2Y9X A;  2ZMX A;  3GWJ A;  3AWZ A;  3AWS A;  1HC1 A;  3W6Q A;  2Y9W A;  4L37 B;  1WX4 A;  3NPY A;  4J6V A;  1BT1 A;  3AWU A;  4OUA A;  3NTM A;  1LL1 A;  1WX2 A;  3WJM B;  5I3B A;  3AWV A;  1HCY A;  4Z0Y A;  1BUG A;  4L37 A;  4P6S A;  2ZMY A;  3HHS B;  1JS8 A;  3NQ5 A;  4YZW A;  5I3A A;  4J6U A;  3NQ0 A;  1LLA A;  3WJM A;  2ZMZ A;  4Z10 A;  4D87 A;  4P6T A;  1WX5 A;  2P3X A;  4HD7 A;  1BT2 A;  4J3P A;  4J3Q A;  2AHL A;  2ZWG A;  1LNL A;  2ZWE A;  4HD6 A;  5I38 A;  1NOL A;  4HD4 A;  4OUA B;  2AHK A;  3NM8 A;  3AWY A;  3AWT A; 
#chains in the Genus database with same CATH topology
 2ZWD A;  4Z0Z A;  3AWX A;  2ZWF A;  4J6T A;  3WKY A;  1OXY A;  5CE9 A;  1WXC A;  4J3R A;  3HHS A;  1BT3 A;  3NQ1 A;  3QJO A;  3W6W A;  3AWW A;  4P6R A;  3AX0 A;  2Y9X A;  2ZMX A;  3GWJ A;  3AWZ A;  3AWS A;  1HC1 A;  3W6Q A;  2Y9W A;  4L37 B;  1WX4 A;  3NPY A;  4J6V A;  1BT1 A;  3AWU A;  4OUA A;  3NTM A;  1LL1 A;  1WX2 A;  3WJM B;  5I3B A;  3AWV A;  1HCY A;  4Z0Y A;  1BUG A;  4L37 A;  4P6S A;  2ZMY A;  3HHS B;  1JS8 A;  3NQ5 A;  4YZW A;  5I3A A;  4J6U A;  3NQ0 A;  1LLA A;  3WJM A;  2ZMZ A;  4Z10 A;  4D87 A;  4P6T A;  1WX5 A;  2P3X A;  4HD7 A;  1BT2 A;  4J3P A;  4J3Q A;  2AHL A;  2ZWG A;  1LNL A;  2ZWE A;  4HD6 A;  5I38 A;  1NOL A;  4HD4 A;  4OUA B;  2AHK A;  3NM8 A;  3AWY A;  3AWT A; 
#chains in the Genus database with same CATH homology
 2ZWD A;  4Z0Z A;  3AWX A;  2ZWF A;  4J6T A;  3WKY A;  1OXY A;  5CE9 A;  1WXC A;  4J3R A;  3HHS A;  1BT3 A;  3NQ1 A;  3QJO A;  3W6W A;  3AWW A;  4P6R A;  3AX0 A;  2Y9X A;  2ZMX A;  3GWJ A;  3AWZ A;  3AWS A;  1HC1 A;  3W6Q A;  2Y9W A;  4L37 B;  1WX4 A;  3NPY A;  4J6V A;  1BT1 A;  3AWU A;  4OUA A;  3NTM A;  1LL1 A;  1WX2 A;  3WJM B;  5I3B A;  3AWV A;  1HCY A;  4Z0Y A;  1BUG A;  4L37 A;  4P6S A;  2ZMY A;  3HHS B;  1JS8 A;  3NQ5 A;  4YZW A;  5I3A A;  4J6U A;  3NQ0 A;  1LLA A;  3WJM A;  2ZMZ A;  4Z10 A;  4D87 A;  4P6T A;  1WX5 A;  2P3X A;  4HD7 A;  1BT2 A;  4J3P A;  4J3Q A;  2AHL A;  2ZWG A;  1LNL A;  2ZWE A;  4HD6 A;  5I38 A;  1NOL A;  4HD4 A;  4OUA B;  2AHK A;  3NM8 A;  3AWY A;  3AWT A; 
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