2ZWFA

Crystal structure of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking the deoxy-form crystal in dioxygen-saturated solution for 80 minutes
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
276
structure length
276
Chain Sequence
TVRKNQATLTADEKRRFVAAVLELKRSGRYDEFVRTHNEFIMSDTDSGERTGHRSPSFLPWHRRFLLDFEQALQSVDSSVTLPYWDWSADRTVRASLWAPDFLGGTGRSTDGRVMDGPFAASTGNWPINVRVDSRTYLRRSLGGSVAELPTRAEVESVLAISAYDLPPYNSASEGFRNHLEGWRGVNLHNRVHVWVGGQMATGVSPNDPVFWLHHAYVDKLWAEWQRRHPDSAYVPTGGTPDVVDLNETMKPWNTVRPADLLDHTAYYTFDALEHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase/metal transport
molecule keywords Tyrosinase
publication title Crystallographic evidence of drastic movement of a copper ion toward the substrate tyrosine for starting hydroxylation reaction of tyrosinase
rcsb
source organism Streptomyces castaneoglobisporus
total genus 108
structure length 276
sequence length 276
ec nomenclature ec 1.14.18.1: Tyrosinase.
pdb deposition date 2008-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00264 Tyrosinase Common central domain of tyrosinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1280.10 Mainly Alpha Orthogonal Bundle di-copper center containing domain from catechol oxidase Di-copper center containing domain from catechol oxidase 2zwfA00
4L37A 3W6WA 3NQ5A 4L37B 5CE9A 4J3RA 5I38A 3NM8A 4D87A 3AWVA 4OUAA 3WKYA 4HD7A 4HD4A 3AWSA 1LLAA 3NTMA 1HC1A 1LNLA 4OUAB 4YZWA 3WJMA 1BT1A 2ZMXA 3AWZA 2AHLA 2AHKA 3QJOA 2ZMZA 1WX5A 2ZWEA 4J6TA 4Z10A 1HCYA 3AWTA 3NQ0A 1WXCA 2ZWGA 3HHSA 4J6UA 4P6RA 3GWJA 4J3QA 4Z0YA 1BUGA 4Z0ZA 3NPYA 2ZWFA 2P3XA 2ZWDA 2ZMYA 3WJMB 3NQ1A 3AWXA 4P6TA 3AWWA 1NOLA 2Y9XA 1LL1A 3AWYA 1OXYA 1WX4A 1JS8A 3HHSB 4HD6A 4P6SA 5I3AA 3AX0A 5I3BA 1BT2A 2Y9WA 4J3PA 3AWUA 4J6VA 3W6QA 1BT3A 1WX2A
chains in the Genus database with same CATH superfamily
4L37A 3W6WA 3NQ5A 4L37B 5CE9A 4J3RA 5I38A 3NM8A 4D87A 3AWVA 4OUAA 3WKYA 4HD7A 4HD4A 3AWSA 1LLAA 3NTMA 1HC1A 1LNLA 4OUAB 4YZWA 3WJMA 1BT1A 2ZMXA 3AWZA 2AHLA 2AHKA 3QJOA 2ZMZA 1WX5A 2ZWEA 4J6TA 4Z10A 1HCYA 3AWTA 3NQ0A 1WXCA 2ZWGA 3HHSA 4J6UA 4P6RA 3GWJA 4J3QA 4Z0YA 1BUGA 4Z0ZA 3NPYA 2ZWFA 2P3XA 2ZWDA 2ZMYA 3WJMB 3NQ1A 3AWXA 4P6TA 3AWWA 1NOLA 2Y9XA 1LL1A 3AWYA 1OXYA 1WX4A 1JS8A 3HHSB 4HD6A 4P6SA 5I3AA 3AX0A 5I3BA 1BT2A 2Y9WA 4J3PA 3AWUA 4J6VA 3W6QA 1BT3A 1WX2A
chains in the Genus database with same CATH topology
4L37A 3W6WA 3NQ5A 4L37B 5CE9A 4J3RA 5I38A 3NM8A 4D87A 3AWVA 4OUAA 3WKYA 4HD7A 4HD4A 3AWSA 1LLAA 3NTMA 1HC1A 1LNLA 4OUAB 4YZWA 3WJMA 1BT1A 2ZMXA 3AWZA 2AHLA 2AHKA 3QJOA 2ZMZA 1WX5A 2ZWEA 4J6TA 4Z10A 1HCYA 3AWTA 3NQ0A 1WXCA 2ZWGA 3HHSA 4J6UA 4P6RA 3GWJA 4J3QA 4Z0YA 1BUGA 4Z0ZA 3NPYA 2ZWFA 2P3XA 2ZWDA 2ZMYA 3WJMB 3NQ1A 3AWXA 4P6TA 3AWWA 1NOLA 2Y9XA 1LL1A 3AWYA 1OXYA 1WX4A 1JS8A 3HHSB 4HD6A 4P6SA 5I3AA 3AX0A 5I3BA 1BT2A 2Y9WA 4J3PA 3AWUA 4J6VA 3W6QA 1BT3A 1WX2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L37 A;  3W6W A;  3NQ5 A;  4L37 B;  5CE9 A;  4J3R A;  5I38 A;  3NM8 A;  4D87 A;  3AWV A;  4OUA A;  3WKY A;  4HD7 A;  4HD4 A;  3AWS A;  1LLA A;  3NTM A;  1HC1 A;  1LNL A;  4OUA B;  4YZW A;  3WJM A;  1BT1 A;  2ZMX A;  3AWZ A;  2AHL A;  2AHK A;  3QJO A;  2ZMZ A;  1WX5 A;  2ZWE A;  4J6T A;  4Z10 A;  1HCY A;  3AWT A;  3NQ0 A;  1WXC A;  2ZWG A;  3HHS A;  4J6U A;  4P6R A;  3GWJ A;  4J3Q A;  4Z0Y A;  1BUG A;  4Z0Z A;  3NPY A;  2ZWF A;  2P3X A;  2ZWD A;  2ZMY A;  3WJM B;  3NQ1 A;  3AWX A;  4P6T A;  3AWW A;  1NOL A;  2Y9X A;  1LL1 A;  3AWY A;  1OXY A;  1WX4 A;  1JS8 A;  3HHS B;  4HD6 A;  4P6S A;  5I3A A;  3AX0 A;  5I3B A;  1BT2 A;  2Y9W A;  4J3P A;  3AWU A;  4J6V A;  3W6Q A;  1BT3 A;  1WX2 A; 
#chains in the Genus database with same CATH topology
 4L37 A;  3W6W A;  3NQ5 A;  4L37 B;  5CE9 A;  4J3R A;  5I38 A;  3NM8 A;  4D87 A;  3AWV A;  4OUA A;  3WKY A;  4HD7 A;  4HD4 A;  3AWS A;  1LLA A;  3NTM A;  1HC1 A;  1LNL A;  4OUA B;  4YZW A;  3WJM A;  1BT1 A;  2ZMX A;  3AWZ A;  2AHL A;  2AHK A;  3QJO A;  2ZMZ A;  1WX5 A;  2ZWE A;  4J6T A;  4Z10 A;  1HCY A;  3AWT A;  3NQ0 A;  1WXC A;  2ZWG A;  3HHS A;  4J6U A;  4P6R A;  3GWJ A;  4J3Q A;  4Z0Y A;  1BUG A;  4Z0Z A;  3NPY A;  2ZWF A;  2P3X A;  2ZWD A;  2ZMY A;  3WJM B;  3NQ1 A;  3AWX A;  4P6T A;  3AWW A;  1NOL A;  2Y9X A;  1LL1 A;  3AWY A;  1OXY A;  1WX4 A;  1JS8 A;  3HHS B;  4HD6 A;  4P6S A;  5I3A A;  3AX0 A;  5I3B A;  1BT2 A;  2Y9W A;  4J3P A;  3AWU A;  4J6V A;  3W6Q A;  1BT3 A;  1WX2 A; 
#chains in the Genus database with same CATH homology
 4L37 A;  3W6W A;  3NQ5 A;  4L37 B;  5CE9 A;  4J3R A;  5I38 A;  3NM8 A;  4D87 A;  3AWV A;  4OUA A;  3WKY A;  4HD7 A;  4HD4 A;  3AWS A;  1LLA A;  3NTM A;  1HC1 A;  1LNL A;  4OUA B;  4YZW A;  3WJM A;  1BT1 A;  2ZMX A;  3AWZ A;  2AHL A;  2AHK A;  3QJO A;  2ZMZ A;  1WX5 A;  2ZWE A;  4J6T A;  4Z10 A;  1HCY A;  3AWT A;  3NQ0 A;  1WXC A;  2ZWG A;  3HHS A;  4J6U A;  4P6R A;  3GWJ A;  4J3Q A;  4Z0Y A;  1BUG A;  4Z0Z A;  3NPY A;  2ZWF A;  2P3X A;  2ZWD A;  2ZMY A;  3WJM B;  3NQ1 A;  3AWX A;  4P6T A;  3AWW A;  1NOL A;  2Y9X A;  1LL1 A;  3AWY A;  1OXY A;  1WX4 A;  1JS8 A;  3HHS B;  4HD6 A;  4P6S A;  5I3A A;  3AX0 A;  5I3B A;  1BT2 A;  2Y9W A;  4J3P A;  3AWU A;  4J6V A;  3W6Q A;  1BT3 A;  1WX2 A; 
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