1YHQU

Crystal structure of azithromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
53
structure length
53
Chain Sequence
RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule keywords 23S Ribosomal RNA
molecule tags Ribosome
total genus 12
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2005-01-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
U PF01246 Ribosomal_L24e Ribosomal protein L24e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.170.20 Mainly Beta Roll Ribosomal Protein L24e; Chain: T; Ribosomal Protein L24e; Chain: T; 1yhqU00
2QA4U 1YJNU 1W2BT 3CCLU 1VQOU 1Q81V 3CCUU 1VQ7U 3CCEU 1KD1V 3I55U 5AN9G 1K9MV 3G4SU 3CC4U 1VQ6U 3I56U 3G6EU 3CMEU 3CCMU 1YHQU 1YIJU 1Q86V 1NJIV 1YI2U 1VQ8U 3CC7U 1M1KV 3CCRU 3CC2U 3CCQU 1VQNU 3CD6U 1K8AV 1Q82V 2OTLU 3OW2T 1VQ5U 1KC8V 1YJWU 1JJ2T 1QVFT 3CCSU 1VQKU 3CXCT 1YJ9U 1VQLU 1VQ9U 1Q7YV 3CCVU 1M90V 1YITU 2OTJU 1N8RV 1S72U 1VQ4U 3CPWT 3G71U 3CMAU 2QEXU 3CCJU 1VQMU 1K73V 1KQST 1QVGT 1VQPU
chains in the Genus database with same CATH superfamily
1VQOU 1VQ7U 5AN9G 3G4SU 1Q86V 1YIJU 1VQ8U 3CCRU 1Q82V 3OW2T 1JJ2T 3CCSU 2OTJU 1JJDA 3ABRA 1W2BT 3CCLU 1Q81V 3ABSA 5H1SY 1VQ6U 3I56U 3CCMU 1YI2U 1VQ5U 2JZ6A 1QVFT 3CXCT 1YJ9U 1M90V 1S72U 3CPWT 3G71U 2QEXU 1KQST 1QVGT 3ABQA 2QA4U 3I55U 1K9MV 5MLCY 3CC4U 1YHQU 3CMEU 3CC7U 3CD6U 3CCQU 1VQNU 1K8AV 2OTLU 3AO0A 1VQLU 1VQ9U 1Q7YV 4UY8X 3CMAU 3CCJU 1VQMU 3ANYA 1NJIV 1VQ4U 1VQPU 1YJNU 3CCUU 3CCEU 3J7ZX 1KD1V 3G6EU 3CC2U 1M1KV 5DM6U 1KC8V 1YJWU 1VQKU 3ABOA 3CCVU 1YITU 1N8RV 1K73V 2QEZA
chains in the Genus database with same CATH topology
2QA4U 1YJNU 1W2BT 3CCLU 1VQOU 1Q81V 3CCUU 1VQ7U 3CCEU 1KD1V 3I55U 5AN9G 1K9MV 3G4SU 3CC4U 1VQ6U 3I56U 3G6EU 3CMEU 3CCMU 1YHQU 1YIJU 1Q86V 1NJIV 1YI2U 1VQ8U 3CC7U 1M1KV 3CCRU 3CC2U 3CCQU 1VQNU 3CD6U 1K8AV 1Q82V 2OTLU 3OW2T 1VQ5U 1KC8V 1YJWU 1JJ2T 1QVFT 3CCSU 1VQKU 3CXCT 1YJ9U 1VQLU 1VQ9U 1Q7YV 3CCVU 1M90V 1YITU 2OTJU 1N8RV 1JJDA 1S72U 1VQ4U 3CPWT 3G71U 3CMAU 2QEXU 3CCJU 1VQMU 1K73V 1KQST 1QVGT 1VQPU
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QA4 U;  1YJN U;  1W2B T;  3CCL U;  1VQO U;  1Q81 V;  3CCU U;  1VQ7 U;  3CCE U;  1KD1 V;  3I55 U;  5AN9 G;  1K9M V;  3G4S U;  3CC4 U;  1VQ6 U;  3I56 U;  3G6E U;  3CME U;  3CCM U;  1YHQ U;  1YIJ U;  1Q86 V;  1NJI V;  1YI2 U;  1VQ8 U;  3CC7 U;  1M1K V;  3CCR U;  3CC2 U;  3CCQ U;  1VQN U;  3CD6 U;  1K8A V;  1Q82 V;  2OTL U;  3OW2 T;  1VQ5 U;  1KC8 V;  1YJW U;  1JJ2 T;  1QVF T;  3CCS U;  1VQK U;  3CXC T;  1YJ9 U;  1VQL U;  1VQ9 U;  1Q7Y V;  3CCV U;  1M90 V;  1YIT U;  2OTJ U;  1N8R V;  1S72 U;  1VQ4 U;  3CPW T;  3G71 U;  3CMA U;  2QEX U;  3CCJ U;  1VQM U;  1K73 V;  1KQS T;  1QVG T;  1VQP U; 
#chains in the Genus database with same CATH topology
 1VQO U;  1VQ7 U;  5AN9 G;  3G4S U;  1Q86 V;  1YIJ U;  1VQ8 U;  3CCR U;  1Q82 V;  3OW2 T;  1JJ2 T;  3CCS U;  2OTJ U;  1JJD A;  3ABR A;  1W2B T;  3CCL U;  1Q81 V;  3ABS A;  5H1S Y;  1VQ6 U;  3I56 U;  3CCM U;  1YI2 U;  1VQ5 U;  2JZ6 A;  1QVF T;  3CXC T;  1YJ9 U;  1M90 V;  1S72 U;  3CPW T;  3G71 U;  2QEX U;  1KQS T;  1QVG T;  3ABQ A;  2QA4 U;  3I55 U;  1K9M V;  5MLC Y;  3CC4 U;  1YHQ U;  3CME U;  3CC7 U;  3CD6 U;  3CCQ U;  1VQN U;  1K8A V;  2OTL U;  3AO0 A;  1VQL U;  1VQ9 U;  1Q7Y V;  4UY8 X;  3CMA U;  3CCJ U;  1VQM U;  3ANY A;  1NJI V;  1VQ4 U;  1VQP U;  1YJN U;  3CCU U;  3CCE U;  3J7Z X;  1KD1 V;  3G6E U;  3CC2 U;  1M1K V;  5DM6 U;  1KC8 V;  1YJW U;  1VQK U;  3ABO A;  3CCV U;  1YIT U;  1N8R V;  1K73 V;  2QEZ A; 
#chains in the Genus database with same CATH homology
 2QA4 U;  1YJN U;  1W2B T;  3CCL U;  1VQO U;  1Q81 V;  3CCU U;  1VQ7 U;  3CCE U;  1KD1 V;  3I55 U;  5AN9 G;  1K9M V;  3G4S U;  3CC4 U;  1VQ6 U;  3I56 U;  3G6E U;  3CME U;  3CCM U;  1YHQ U;  1YIJ U;  1Q86 V;  1NJI V;  1YI2 U;  1VQ8 U;  3CC7 U;  1M1K V;  3CCR U;  3CC2 U;  3CCQ U;  1VQN U;  3CD6 U;  1K8A V;  1Q82 V;  2OTL U;  3OW2 T;  1VQ5 U;  1KC8 V;  1YJW U;  1JJ2 T;  1QVF T;  3CCS U;  1VQK U;  3CXC T;  1YJ9 U;  1VQL U;  1VQ9 U;  1Q7Y V;  3CCV U;  1M90 V;  1YIT U;  2OTJ U;  1N8R V;  1JJD A;  1S72 U;  1VQ4 U;  3CPW T;  3G71 U;  3CMA U;  2QEX U;  3CCJ U;  1VQM U;  1K73 V;  1KQS T;  1QVG T;  1VQP U; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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