3G4SU

Co-crystal structure of tiamulin bound to the large ribosomal subunit
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
53
structure length
53
Chain Sequence
RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ribosome
molecule keywords 23S ribosomal RNA
publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
total genus 6
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2009-02-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.170.20 Mainly Beta Roll Ribosomal Protein L24e; Chain: T; Ribosomal Protein L24e; Chain: T; 3g4sU00
1VQPU 3CCLU 1W2BT 1YJWU 3CCJU 1Q81V 1Q86V 3CCQU 3CPWT 3CMEU 1KD1V 1VQ5U 1VQ8U 2OTJU 1N8RV 1YI2U 1M90V 1NJIV 3G71U 1K73V 1S72U 1QVFT 3G6EU 1K9MV 3CCUU 3CMAU 3CXCT 3OW2T 1YITU 1VQOU 1Q82V 2OTLU 3CC4U 1VQ6U 1JJ2T 1KC8V 2QEXU 3CCEU 1VQKU 5AN9G 3CCVU 1VQMU 1QVGT 1M1KV 1VQNU 3CC2U 1YHQU 1YJ9U 3CCRU 3CCSU 1VQ4U 3CC7U 3CCMU 3I55U 1KQST 3G4SU 1Q7YV 1VQ9U 3I56U 2QA4U 1VQ7U 1YJNU 1K8AV 1VQLU 3CD6U 1YIJU
chains in the Genus database with same CATH superfamily
1KD1V 3G71U 1S72U 3CCUU 3ABSA 1VQ6U 2OTLU 3CC4U 1YJ9U 5H1SY 3CC7U 3I55U 3CD6U 1Q81V 3CCQU 3CPWT 3CMEU 1N8RV 2QEZA 3G6EU 1KC8V 2QEXU 5AN9G 1QVGT 3CC2U 5DM6U 1JJDA 3ABRA 1KQST 1VQ4U 3OW2T 1VQ7U 1YJNU 1K8AV 1VQLU 3CCLU 3CCJU 1VQ8U 1NJIV 1QVFT 3AO0A 3CXCT 1YITU 5MLCY 1JJ2T 1VQKU 3CCVU 1VQMU 1YHQU 4UY8X 3CCMU 3G4SU 2QA4U 3J7ZX 3ABOA 1VQPU 1W2BT 1YJWU 3ABQA 1Q86V 2OTJU 1VQ5U 1YI2U 1M90V 1K73V 1K9MV 3CMAU 1Q82V 1VQOU 3CCEU 2JZ6A 1VQNU 1M1KV 3ANYA 3CCRU 3CCSU 1Q7YV 1VQ9U 3I56U 1YIJU
chains in the Genus database with same CATH topology
1VQPU 3CCLU 1W2BT 1YJWU 3CCJU 1Q81V 1Q86V 3CCQU 3CPWT 3CMEU 1KD1V 1VQ5U 1VQ8U 2OTJU 1N8RV 1YI2U 1M90V 1NJIV 3G71U 1K73V 1S72U 1QVFT 3G6EU 1K9MV 3CCUU 3CMAU 3CXCT 3OW2T 1YITU 1VQOU 1Q82V 2OTLU 3CC4U 1VQ6U 1JJ2T 1KC8V 2QEXU 3CCEU 1VQKU 5AN9G 3CCVU 1VQMU 1QVGT 1M1KV 1VQNU 3CC2U 1YHQU 1YJ9U 3CCRU 3CCSU 1JJDA 1VQ4U 3CC7U 3CCMU 3I55U 1KQST 3G4SU 1Q7YV 1VQ9U 3I56U 2QA4U 1VQ7U 1YJNU 1K8AV 1VQLU 3CD6U 1YIJU
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQP U;  3CCL U;  1W2B T;  1YJW U;  3CCJ U;  1Q81 V;  1Q86 V;  3CCQ U;  3CPW T;  3CME U;  1KD1 V;  1VQ5 U;  1VQ8 U;  2OTJ U;  1N8R V;  1YI2 U;  1M90 V;  1NJI V;  3G71 U;  1K73 V;  1S72 U;  1QVF T;  3G6E U;  1K9M V;  3CCU U;  3CMA U;  3CXC T;  3OW2 T;  1YIT U;  1VQO U;  1Q82 V;  2OTL U;  3CC4 U;  1VQ6 U;  1JJ2 T;  1KC8 V;  2QEX U;  3CCE U;  1VQK U;  5AN9 G;  3CCV U;  1VQM U;  1QVG T;  1M1K V;  1VQN U;  3CC2 U;  1YHQ U;  1YJ9 U;  3CCR U;  3CCS U;  1VQ4 U;  3CC7 U;  3CCM U;  3I55 U;  1KQS T;  3G4S U;  1Q7Y V;  1VQ9 U;  3I56 U;  2QA4 U;  1VQ7 U;  1YJN U;  1K8A V;  1VQL U;  3CD6 U;  1YIJ U; 
#chains in the Genus database with same CATH topology
 1KD1 V;  3G71 U;  1S72 U;  3CCU U;  3ABS A;  1VQ6 U;  2OTL U;  3CC4 U;  1YJ9 U;  5H1S Y;  3CC7 U;  3I55 U;  3CD6 U;  1Q81 V;  3CCQ U;  3CPW T;  3CME U;  1N8R V;  2QEZ A;  3G6E U;  1KC8 V;  2QEX U;  5AN9 G;  1QVG T;  3CC2 U;  5DM6 U;  1JJD A;  3ABR A;  1KQS T;  1VQ4 U;  3OW2 T;  1VQ7 U;  1YJN U;  1K8A V;  1VQL U;  3CCL U;  3CCJ U;  1VQ8 U;  1NJI V;  1QVF T;  3AO0 A;  3CXC T;  1YIT U;  5MLC Y;  1JJ2 T;  1VQK U;  3CCV U;  1VQM U;  1YHQ U;  4UY8 X;  3CCM U;  3G4S U;  2QA4 U;  3J7Z X;  3ABO A;  1VQP U;  1W2B T;  1YJW U;  3ABQ A;  1Q86 V;  2OTJ U;  1VQ5 U;  1YI2 U;  1M90 V;  1K73 V;  1K9M V;  3CMA U;  1Q82 V;  1VQO U;  3CCE U;  2JZ6 A;  1VQN U;  1M1K V;  3ANY A;  3CCR U;  3CCS U;  1Q7Y V;  1VQ9 U;  3I56 U;  1YIJ U; 
#chains in the Genus database with same CATH homology
 1VQP U;  3CCL U;  1W2B T;  1YJW U;  3CCJ U;  1Q81 V;  1Q86 V;  3CCQ U;  3CPW T;  3CME U;  1KD1 V;  1VQ5 U;  1VQ8 U;  2OTJ U;  1N8R V;  1YI2 U;  1M90 V;  1NJI V;  3G71 U;  1K73 V;  1S72 U;  1QVF T;  3G6E U;  1K9M V;  3CCU U;  3CMA U;  3CXC T;  3OW2 T;  1YIT U;  1VQO U;  1Q82 V;  2OTL U;  3CC4 U;  1VQ6 U;  1JJ2 T;  1KC8 V;  2QEX U;  3CCE U;  1VQK U;  5AN9 G;  3CCV U;  1VQM U;  1QVG T;  1M1K V;  1VQN U;  3CC2 U;  1YHQ U;  1YJ9 U;  3CCR U;  3CCS U;  1JJD A;  1VQ4 U;  3CC7 U;  3CCM U;  3I55 U;  1KQS T;  3G4S U;  1Q7Y V;  1VQ9 U;  3I56 U;  2QA4 U;  1VQ7 U;  1YJN U;  1K8A V;  1VQL U;  3CD6 U;  1YIJ U; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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