1YI2U

Crystal structure of erythromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
53
structure length
53
Chain Sequence
RECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule keywords 23S Ribosomal RNA
molecule tags Ribosome
total genus 11
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2005-01-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
U PF01246 Ribosomal_L24e Ribosomal protein L24e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.170.20 Mainly Beta Roll Ribosomal Protein L24e; Chain: T; Ribosomal Protein L24e; Chain: T; 1yi2U00
1S72U 3CMEU 3CCUU 1VQ4U 1YIJU 2QEXU 1YJ9U 1VQMU 1YHQU 3CCSU 3CCEU 1Q82V 1QVGT 3CC2U 1K8AV 1M1KV 1N8RV 3OW2T 3CCLU 1Q7YV 3G6EU 3G4SU 3I55U 2QA4U 2OTLU 3CC7U 3CCJU 1VQPU 1KD1V 1VQ8U 1VQNU 1VQOU 1VQ7U 1YI2U 1K73V 1M90V 5AN9G 1QVFT 3CPWT 1VQ9U 3CXCT 3CMAU 1NJIV 1KC8V 1YJWU 1VQKU 3I56U 1VQ6U 1VQ5U 2OTJU 3G71U 1YJNU 3CCQU 1VQLU 3CD6U 3CCRU 1Q81V 3CCVU 3CC4U 1K9MV 1JJ2T 1Q86V 1KQST 1YITU 1W2BT 3CCMU
chains in the Genus database with same CATH superfamily
3CCUU 3ABSA 1VQMU 1YHQU 3CCSU 1Q82V 1QVGT 1K8AV 3CCLU 3I55U 3CC7U 1VQOU 1K73V 5AN9G 3CMAU 1VQKU 1Q81V 3CC4U 1Q86V 3CMEU 3AO0A 1VQ4U 3ABRA 3J7ZX 3OW2T 2OTLU 1VQPU 1VQNU 1YI2U 1VQ9U 2JZ6A 1JJDA 1KC8V 3I56U 1VQLU 3CCVU 1JJ2T 1KQST 1W2BT 1YIJU 3CC2U 1N8RV 1Q7YV 3G6EU 2QA4U 4UY8X 3ANYA 3ABQA 3CXCT 1NJIV 1YJWU 3CCRU 1K9MV 1S72U 3ABOA 2QEXU 1YJ9U 3CCEU 1M1KV 3G4SU 3CCJU 1KD1V 1VQ8U 1VQ7U 1M90V 1QVFT 5H1SY 3CPWT 2QEZA 1VQ6U 1VQ5U 2OTJU 5MLCY 3G71U 1YJNU 3CCQU 3CD6U 5DM6U 1YITU 3CCMU
chains in the Genus database with same CATH topology
1S72U 3CMEU 3CCUU 1VQ4U 1YIJU 2QEXU 1YJ9U 1VQMU 1YHQU 3CCSU 3CCEU 1Q82V 1QVGT 3CC2U 1K8AV 1M1KV 1N8RV 3OW2T 3CCLU 1Q7YV 3G6EU 3G4SU 3I55U 2QA4U 2OTLU 3CC7U 3CCJU 1VQPU 1KD1V 1VQ8U 1VQNU 1VQOU 1VQ7U 1YI2U 1K73V 1M90V 5AN9G 1QVFT 3CPWT 1VQ9U 3CXCT 3CMAU 1JJDA 1NJIV 1KC8V 1YJWU 1VQKU 3I56U 1VQ6U 1VQ5U 2OTJU 3G71U 1YJNU 3CCQU 1VQLU 3CD6U 3CCRU 1Q81V 3CCVU 3CC4U 1K9MV 1JJ2T 1Q86V 1KQST 1YITU 1W2BT 3CCMU
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1S72 U;  3CME U;  3CCU U;  1VQ4 U;  1YIJ U;  2QEX U;  1YJ9 U;  1VQM U;  1YHQ U;  3CCS U;  3CCE U;  1Q82 V;  1QVG T;  3CC2 U;  1K8A V;  1M1K V;  1N8R V;  3OW2 T;  3CCL U;  1Q7Y V;  3G6E U;  3G4S U;  3I55 U;  2QA4 U;  2OTL U;  3CC7 U;  3CCJ U;  1VQP U;  1KD1 V;  1VQ8 U;  1VQN U;  1VQO U;  1VQ7 U;  1YI2 U;  1K73 V;  1M90 V;  5AN9 G;  1QVF T;  3CPW T;  1VQ9 U;  3CXC T;  3CMA U;  1NJI V;  1KC8 V;  1YJW U;  1VQK U;  3I56 U;  1VQ6 U;  1VQ5 U;  2OTJ U;  3G71 U;  1YJN U;  3CCQ U;  1VQL U;  3CD6 U;  3CCR U;  1Q81 V;  3CCV U;  3CC4 U;  1K9M V;  1JJ2 T;  1Q86 V;  1KQS T;  1YIT U;  1W2B T;  3CCM U; 
#chains in the Genus database with same CATH topology
 3CCU U;  3ABS A;  1VQM U;  1YHQ U;  3CCS U;  1Q82 V;  1QVG T;  1K8A V;  3CCL U;  3I55 U;  3CC7 U;  1VQO U;  1K73 V;  5AN9 G;  3CMA U;  1VQK U;  1Q81 V;  3CC4 U;  1Q86 V;  3CME U;  3AO0 A;  1VQ4 U;  3ABR A;  3J7Z X;  3OW2 T;  2OTL U;  1VQP U;  1VQN U;  1YI2 U;  1VQ9 U;  2JZ6 A;  1JJD A;  1KC8 V;  3I56 U;  1VQL U;  3CCV U;  1JJ2 T;  1KQS T;  1W2B T;  1YIJ U;  3CC2 U;  1N8R V;  1Q7Y V;  3G6E U;  2QA4 U;  4UY8 X;  3ANY A;  3ABQ A;  3CXC T;  1NJI V;  1YJW U;  3CCR U;  1K9M V;  1S72 U;  3ABO A;  2QEX U;  1YJ9 U;  3CCE U;  1M1K V;  3G4S U;  3CCJ U;  1KD1 V;  1VQ8 U;  1VQ7 U;  1M90 V;  1QVF T;  5H1S Y;  3CPW T;  2QEZ A;  1VQ6 U;  1VQ5 U;  2OTJ U;  5MLC Y;  3G71 U;  1YJN U;  3CCQ U;  3CD6 U;  5DM6 U;  1YIT U;  3CCM U; 
#chains in the Genus database with same CATH homology
 1S72 U;  3CME U;  3CCU U;  1VQ4 U;  1YIJ U;  2QEX U;  1YJ9 U;  1VQM U;  1YHQ U;  3CCS U;  3CCE U;  1Q82 V;  1QVG T;  3CC2 U;  1K8A V;  1M1K V;  1N8R V;  3OW2 T;  3CCL U;  1Q7Y V;  3G6E U;  3G4S U;  3I55 U;  2QA4 U;  2OTL U;  3CC7 U;  3CCJ U;  1VQP U;  1KD1 V;  1VQ8 U;  1VQN U;  1VQO U;  1VQ7 U;  1YI2 U;  1K73 V;  1M90 V;  5AN9 G;  1QVF T;  3CPW T;  1VQ9 U;  3CXC T;  3CMA U;  1JJD A;  1NJI V;  1KC8 V;  1YJW U;  1VQK U;  3I56 U;  1VQ6 U;  1VQ5 U;  2OTJ U;  3G71 U;  1YJN U;  3CCQ U;  1VQL U;  3CD6 U;  3CCR U;  1Q81 V;  3CCV U;  3CC4 U;  1K9M V;  1JJ2 T;  1Q86 V;  1KQS T;  1YIT U;  1W2B T;  3CCM U; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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