2CSCA

Structure of ternary complexes of citrate synthase with d-and l-malate: mechanistic implications
Total Genus 149
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
149
sequence length
433
structure length
429
Chain Sequence
ASSTNLKDVLAALIPKEQARIKTFRQQHGGTALGQITVDMSYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKGGGGEPLPEGLFWLLVTGQIPTGAQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGILRTKYWEMVYESAMDLIAKLPCVAAKIYRNLYRAGSSIGAIDSKLDWSHNFTNMLGYTDAQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLGWLAQLQKAAGADASLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPGDPMFKLVAQLYKIVPNVLLEQGAAANPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLIAL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title 1.9-A structures of ternary complexes of citrate synthase with D- and L-malate: mechanistic implications.
pubmed doi rcsb
molecule tags Lyase
source organism Gallus gallus
molecule keywords CITRATE SYNTHASE
total genus 149
structure length 429
sequence length 433
ec nomenclature ec 2.3.3.1: Citrate (Si)-synthase.
pdb deposition date 1990-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00285 Citrate_synt Citrate synthase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.230.10 Mainly Alpha Orthogonal Bundle Cytochrome p450-Terp; domain 2 Cytochrome P450-Terp, domain 2 2cscA02
1.10.580.10 Mainly Alpha Orthogonal Bundle Citrate Synthase; domain 1 Citrate Synthase, domain 1 2cscA01
2C6XA 2CTSA 1AJ8A 2IFCA 5CSCB 3ENJA 5CTSA 5CSCA 1AL6A 2P2WA 1AMZA 4CTSA 1CSRA 1OWBA 4TVMA 3TQGA 4JAGA 1CSCA 2H12A 3CSCA 3HWKA 4CSCA 1NXGA 1CSHA 2CSCA 2R26A 6CSCA 3O8JA 4YBOA 4JADA 2IBPA 3MSUA 1OWCA 1NXEA 1IXEA 1CSSA 1VGMA 4JAEA 1A59A 1CTSA 4JAFA 6CTSA 1IOMA 1CSIA 1O7XA 4G6BA 4E6YA 4XGHA 2R9EA 1VGPA
chains in the Genus database with same CATH superfamily
2C6XA 2CTSA 1AJ8A 2IFCA 5CSCB 3ENJA 5CTSA 5CSCA 1AL6A 2P2WA 1AMZA 4CTSA 1CSRA 1OWBA 4TVMA 3TQGA 4JAGA 1CSCA 2H12A 3CSCA 3HWKA 4CSCA 1NXGA 1CSHA 2CSCA 2R26A 6CSCA 3O8JA 4YBOA 4JADA 2IBPA 3MSUA 1OWCA 1NXEA 1IXEA 1CSSA 1VGMA 4JAEA 1A59A 1CTSA 4JAFA 6CTSA 1IOMA 1CSIA 1O7XA 4G6BA 4XGHA 4E6YA 2R9EA 1VGPA
chains in the Genus database with same CATH topology
2C6XA 2CTSA 1AJ8A 2IFCA 5CSCB 3ENJA 5CTSA 5CSCA 1AL6A 2P2WA 1AMZA 4CTSA 1CSRA 1OWBA 4TVMA 3TQGA 4JAGA 1CSCA 2H12A 3CSCA 3HWKA 4CSCA 1NXGA 1CSHA 2CSCA 2R26A 6CSCA 3O8JA 4YBOA 4JADA 2IBPA 3MSUA 1OWCA 1NXEA 1IXEA 1CSSA 1VGMA 4JAEA 1A59A 1CTSA 4JAFA 6CTSA 1IOMA 1CSIA 1O7XA 4G6BA 4E6YA 4XGHA 2R9EA 1VGPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2C6X A;  2CTS A;  1AJ8 A;  2IFC A;  5CSC B;  3ENJ A;  5CTS A;  5CSC A;  1AL6 A;  2P2W A;  1AMZ A;  4CTS A;  1CSR A;  1OWB A;  4TVM A;  3TQG A;  4JAG A;  1CSC A;  2H12 A;  3CSC A;  3HWK A;  4CSC A;  1NXG A;  1CSH A;  2CSC A;  2R26 A;  6CSC A;  3O8J A;  4YBO A;  4JAD A;  2IBP A;  3MSU A;  1OWC A;  1NXE A;  1IXE A;  1CSS A;  1VGM A;  4JAE A;  1A59 A;  1CTS A;  4JAF A;  6CTS A;  1IOM A;  1CSI A;  1O7X A;  4G6B A;  4E6Y A;  4XGH A;  2R9E A;  1VGP A; 
#chains in the Genus database with same CATH topology
 2C6X A;  2CTS A;  1AJ8 A;  2IFC A;  5CSC B;  3ENJ A;  5CTS A;  5CSC A;  1AL6 A;  2P2W A;  1AMZ A;  4CTS A;  1CSR A;  1OWB A;  4TVM A;  3TQG A;  4JAG A;  1CSC A;  2H12 A;  3CSC A;  3HWK A;  4CSC A;  1NXG A;  1CSH A;  2CSC A;  2R26 A;  6CSC A;  3O8J A;  4YBO A;  4JAD A;  2IBP A;  3MSU A;  1OWC A;  1NXE A;  1IXE A;  1CSS A;  1VGM A;  4JAE A;  1A59 A;  1CTS A;  4JAF A;  6CTS A;  1IOM A;  1CSI A;  1O7X A;  4G6B A;  4XGH A;  4E6Y A;  2R9E A;  1VGP A; 
#chains in the Genus database with same CATH homology
 2C6X A;  2CTS A;  1AJ8 A;  2IFC A;  5CSC B;  3ENJ A;  5CTS A;  5CSC A;  1AL6 A;  2P2W A;  1AMZ A;  4CTS A;  1CSR A;  1OWB A;  4TVM A;  3TQG A;  4JAG A;  1CSC A;  2H12 A;  3CSC A;  3HWK A;  4CSC A;  1NXG A;  1CSH A;  2CSC A;  2R26 A;  6CSC A;  3O8J A;  4YBO A;  4JAD A;  2IBP A;  3MSU A;  1OWC A;  1NXE A;  1IXE A;  1CSS A;  1VGM A;  4JAE A;  1A59 A;  1CTS A;  4JAF A;  6CTS A;  1IOM A;  1CSI A;  1O7X A;  4G6B A;  4E6Y A;  4XGH A;  2R9E A;  1VGP A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...