2CTS | Genus

Total Genus 153

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	153
sequence length	437
structure length	437
Chain Sequence	ASSTNLKDILADLIPKEQARIKTFRQQHGNTAVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGYSIPECQKMLPKAKGGEEPLPEGLFWLLVTGQIPTEEQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGIHRTKYWELIYEDCMDLIAKLPCVAAKIYRNLYREGSSIGAIDSKLDWSHNFTNMLGYTDAQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPHDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLIKLVDSK

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Oxo-acid-lyase
source organism	Sus scrofa
publication title	Crystallographic refinement and atomic models of two different forms of citrate synthase at 2.7 and 1.7 A resolution. pubmed doi rcsb
molecule keywords	CITRATE SYNTHASE
total genus	153
structure length	437
sequence length	437
ec nomenclature	ec 2.3.3.1: Citrate (Si)-synthase.
pdb deposition date	1984-01-27

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00285	Citrate_synt	Citrate synthase, C-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.230.10	Mainly Alpha	Orthogonal Bundle	Cytochrome p450-Terp; domain 2	Cytochrome P450-Terp, domain 2	2ctsA02
1.10.580.10	Mainly Alpha	Orthogonal Bundle	Citrate Synthase; domain 1	Citrate Synthase, domain 1	2ctsA01

4YBOA 2R26A 3HWKA 1IOMA 6CSCA 2H12A 1IXEA 3TQGA 2CSCA 2P2WA 1OWBA 1AL6A 1CSIA 4E6YA 4XGHA 2R9EA 2IFCA 4CSCA 1A59A 4CTSA 1CSSA 4JAGA 5CSCB 6CTSA 2IBPA 3CSCA 2CTSA 1VGMA 1CTSA 1O7XA 3O8JA 4G6BA 1CSRA 3MSUA 1NXEA 3ENJA 1VGPA 1AJ8A 5CSCA 4JAEA 4JADA 1CSHA 1AMZA 4TVMA 5CTSA 1NXGA 4JAFA 1CSCA 1OWCA 2C6XA
chains in the Genus database with same CATH superfamily

4YBOA 2R26A 3HWKA 1IOMA 6CSCA 2H12A 1IXEA 3TQGA 2CSCA 2P2WA 1OWBA 1AL6A 1CSIA 4XGHA 4E6YA 2R9EA 2IFCA 4CSCA 1A59A 4CTSA 1CSSA 4JAGA 5CSCB 6CTSA 2IBPA 3CSCA 2CTSA 1VGMA 1CTSA 1O7XA 3O8JA 4G6BA 1CSRA 3MSUA 1NXEA 3ENJA 1VGPA 1AJ8A 5CSCA 4JAEA 4JADA 1CSHA 1AMZA 4TVMA 5CTSA 1NXGA 4JAFA 1CSCA 1OWCA 2C6XA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4YBO A;  2R26 A;  3HWK A;  1IOM A;  6CSC A;  2H12 A;  1IXE A;  3TQG A;  2CSC A;  2P2W A;  1OWB A;  1AL6 A;  1CSI A;  4E6Y A;  4XGH A;  2R9E A;  2IFC A;  4CSC A;  1A59 A;  4CTS A;  1CSS A;  4JAG A;  5CSC B;  6CTS A;  2IBP A;  3CSC A;  2CTS A;  1VGM A;  1CTS A;  1O7X A;  3O8J A;  4G6B A;  1CSR A;  3MSU A;  1NXE A;  3ENJ A;  1VGP A;  1AJ8 A;  5CSC A;  4JAE A;  4JAD A;  1CSH A;  1AMZ A;  4TVM A;  5CTS A;  1NXG A;  4JAF A;  1CSC A;  1OWC A;  2C6X A; 
#chains in the Genus database with same CATH topology
 4YBO A;  2R26 A;  3HWK A;  1IOM A;  6CSC A;  2H12 A;  1IXE A;  3TQG A;  2CSC A;  2P2W A;  1OWB A;  1AL6 A;  1CSI A;  4XGH A;  4E6Y A;  2R9E A;  2IFC A;  4CSC A;  1A59 A;  4CTS A;  1CSS A;  4JAG A;  5CSC B;  6CTS A;  2IBP A;  3CSC A;  2CTS A;  1VGM A;  1CTS A;  1O7X A;  3O8J A;  4G6B A;  1CSR A;  3MSU A;  1NXE A;  3ENJ A;  1VGP A;  1AJ8 A;  5CSC A;  4JAE A;  4JAD A;  1CSH A;  1AMZ A;  4TVM A;  5CTS A;  1NXG A;  4JAF A;  1CSC A;  1OWC A;  2C6X A; 
#chains in the Genus database with same CATH homology
 4YBO A;  2R26 A;  3HWK A;  1IOM A;  6CSC A;  2H12 A;  1IXE A;  3TQG A;  2CSC A;  2P2W A;  1OWB A;  1AL6 A;  1CSI A;  4E6Y A;  4XGH A;  2R9E A;  2IFC A;  4CSC A;  1A59 A;  4CTS A;  1CSS A;  4JAG A;  5CSC B;  6CTS A;  2IBP A;  3CSC A;  2CTS A;  1VGM A;  1CTS A;  1O7X A;  3O8J A;  4G6B A;  1CSR A;  3MSU A;  1NXE A;  3ENJ A;  1VGP A;  1AJ8 A;  5CSC A;  4JAE A;  4JAD A;  1CSH A;  1AMZ A;  4TVM A;  5CTS A;  1NXG A;  4JAF A;  1CSC A;  1OWC A;  2C6X A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2CTSA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations