2EZWA

Solution structure of the docking and dimerization domain of the type i alpha regulatory subunit of protein kinase a (rialpha d/d)
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
50
structure length
50
Chain Sequence
SLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFEKLEKEEAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Related Protein-Protein Interaction Modules Present Drastically Different Surface Topographies Despite A Conserved Helical Platform
pubmed doi rcsb
molecule keywords cAMP-dependent protein kinase type I-alpha regulatory subuni
molecule tags Transferase
source organism Bos taurus
total genus 10
structure length 50
sequence length 50
chains with identical sequence B
ec nomenclature ec 2.7.1.37: Transferred entry: 2.7.11.1, 2.7.11.8, 2.7.11.9, 2.7.11.10, 2.7.11.11,
pdb deposition date 2005-11-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02197 RIIa Regulatory subunit of type II PKA R-subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.890.10 Mainly Alpha Up-down Bundle cAMP-dependent Protein Kinase, Chain A cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 2ezwA00
4RT4A 2DRNA 3G36A 4ZP3A 3IM3A 2H9RA 4F9KA 2KYGA 5HVZA 2EZWA 1L6EA 4RTAA 3IM4A 2IZYA 1R2AA 4RIQA
chains in the Genus database with same CATH superfamily
3QDEA 3G36A 3UFEA 3QG0A 2K9QA 3QFYA 2CQTA 3ACSA 1R2AA 4RIQA 3PMIA 3IM3A 2CB9A 2KYGA 3GWHA 3S4DA 2EZWA 5HVZA 3AFJA 3RSYA 3S4BA 4ZP3A 2KNGA 3QFZA 2CBGA 2CQSA 3S4AA 4RTAA 3ACTA 3IM4A 3RRSA 2IZYA 2OUTA 4RT4A 2RQYA 2DRNA 4F9KA 3S4CA 2H9RA 1L6EA 2I15A
chains in the Genus database with same CATH topology
4RT4A 2DRNA 3G36A 4ZP3A 3IM3A 2H9RA 4F9KA 2KYGA 5HVZA 2EZWA 1L6EA 4RTAA 3IM4A 2IZYA 1R2AA 4RIQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RT4 A;  2DRN A;  3G36 A;  4ZP3 A;  3IM3 A;  2H9R A;  4F9K A;  2KYG A;  5HVZ A;  2EZW A;  1L6E A;  4RTA A;  3IM4 A;  2IZY A;  1R2A A;  4RIQ A; 
#chains in the Genus database with same CATH topology
 3QDE A;  3G36 A;  3UFE A;  3QG0 A;  2K9Q A;  3QFY A;  2CQT A;  3ACS A;  1R2A A;  4RIQ A;  3PMI A;  3IM3 A;  2CB9 A;  2KYG A;  3GWH A;  3S4D A;  2EZW A;  5HVZ A;  3AFJ A;  3RSY A;  3S4B A;  4ZP3 A;  2KNG A;  3QFZ A;  2CBG A;  2CQS A;  3S4A A;  4RTA A;  3ACT A;  3IM4 A;  3RRS A;  2IZY A;  2OUT A;  4RT4 A;  2RQY A;  2DRN A;  4F9K A;  3S4C A;  2H9R A;  1L6E A;  2I15 A; 
#chains in the Genus database with same CATH homology
 4RT4 A;  2DRN A;  3G36 A;  4ZP3 A;  3IM3 A;  2H9R A;  4F9K A;  2KYG A;  5HVZ A;  2EZW A;  1L6E A;  4RTA A;  3IM4 A;  2IZY A;  1R2A A;  4RIQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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