2FMME

Crystal structure of emsy-hp1 complex
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
118
structure length
118
Chain Sequence
GPLDLSRDECKRILRKLELEAYAGVISALRAQGDLTKEKKDLLGELSKVLSISTERHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the HP1-EMSY complex reveals an unusual mode of HP1 binding.
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords Protein EMSY
total genus 39
structure length 118
sequence length 118
ec nomenclature
pdb deposition date 2006-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF03735 ENT ENT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1240.40 Mainly Alpha Orthogonal Bundle Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 2fmmE00
1UTUA 1UZ3A 2FMME
chains in the Genus database with same CATH superfamily
1SV1A 1UTUA 3BJDA 1UZ3A 3WHPA 4G86A 1BMTA 3L9TA 1SUYA 3IVAA 1K7YA 1SLYA 3BULA 1R8JA 5C8DA 1Q6BA 2I2XB 2FMME 2PBIA 3M1MA 3H20A 1QSAA 4X8QA 1K98A 2J70A 2J6YA 1QTEA 1V2ZA 4JGIA 1W53A 4HH3C 1R5QA 3IV9A 5C5EA 2J6ZA 4HEHA 4M0MA 3EZXA 1Q6AA
chains in the Genus database with same CATH topology
3M1MA 3H20A 3L9TA 1UTUA 4M0MA 4X8QA 1UZ3A 2FMME 2PBIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UTU A;  1UZ3 A;  2FMM E; 
#chains in the Genus database with same CATH topology
 1SV1 A;  1UTU A;  3BJD A;  1UZ3 A;  3WHP A;  4G86 A;  1BMT A;  3L9T A;  1SUY A;  3IVA A;  1K7Y A;  1SLY A;  3BUL A;  1R8J A;  5C8D A;  1Q6B A;  2I2X B;  2FMM E;  2PBI A;  3M1M A;  3H20 A;  1QSA A;  4X8Q A;  1K98 A;  2J70 A;  2J6Y A;  1QTE A;  1V2Z A;  4JGI A;  1W53 A;  4HH3 C;  1R5Q A;  3IV9 A;  5C5E A;  2J6Z A;  4HEH A;  4M0M A;  3EZX A;  1Q6A A; 
#chains in the Genus database with same CATH homology
 3M1M A;  3H20 A;  3L9T A;  1UTU A;  4M0M A;  4X8Q A;  1UZ3 A;  2FMM E;  2PBI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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