2H9RA

Docking and dimerization domain (d/d) of the regulatory subunit of the type ii-alpha camp-dependent protein kinase a associated with a peptide derived from an a-kinase anchoring protein (akap)
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
46
structure length
46
Chain Sequence
HMGHIQIPPGLTELLQGYTVEVLRQQPPDLVDFAVEYFTRLREARR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes.
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords cAMP-dependent protein kinase type II-alpha regulatory subun
total genus 11
structure length 46
sequence length 46
chains with identical sequence B
ec nomenclature ec 2.7.1.37: Transferred entry: 2.7.11.1, 2.7.11.8, 2.7.11.9, 2.7.11.10, 2.7.11.11,
pdb deposition date 2006-06-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02197 RIIa Regulatory subunit of type II PKA R-subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.890.10 Mainly Alpha Up-down Bundle cAMP-dependent Protein Kinase, Chain A cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 2h9rA00
1R2AA 2KYGA 4RT4A 4RIQA 5HVZA 4RTAA 2DRNA 4ZP3A 2EZWA 3IM4A 2IZYA 3G36A 4F9KA 1L6EA 2H9RA 3IM3A
chains in the Genus database with same CATH superfamily
2KYGA 2CQSA 2K9QA 3S4DA 3S4AA 1L6EA 3QFYA 4RT4A 2CQTA 2CBGA 2RQYA 3GWHA 3IM4A 3ACTA 4F9KA 3QDEA 3PMIA 3RRSA 4RIQA 4RTAA 3S4CA 2CB9A 3AFJA 2IZYA 3ACSA 2H9RA 3QG0A 3QFZA 2KNGA 3UFEA 5HVZA 3S4BA 2DRNA 4ZP3A 2OUTA 2EZWA 3G36A 2I15A 3RSYA 1R2AA 3IM3A
chains in the Genus database with same CATH topology
1R2AA 2KYGA 4RT4A 4RIQA 5HVZA 4RTAA 2DRNA 4ZP3A 2EZWA 3IM4A 2IZYA 3G36A 4F9KA 1L6EA 2H9RA 3IM3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R2A A;  2KYG A;  4RT4 A;  4RIQ A;  5HVZ A;  4RTA A;  2DRN A;  4ZP3 A;  2EZW A;  3IM4 A;  2IZY A;  3G36 A;  4F9K A;  1L6E A;  2H9R A;  3IM3 A; 
#chains in the Genus database with same CATH topology
 2KYG A;  2CQS A;  2K9Q A;  3S4D A;  3S4A A;  1L6E A;  3QFY A;  4RT4 A;  2CQT A;  2CBG A;  2RQY A;  3GWH A;  3IM4 A;  3ACT A;  4F9K A;  3QDE A;  3PMI A;  3RRS A;  4RIQ A;  4RTA A;  3S4C A;  2CB9 A;  3AFJ A;  2IZY A;  3ACS A;  2H9R A;  3QG0 A;  3QFZ A;  2KNG A;  3UFE A;  5HVZ A;  3S4B A;  2DRN A;  4ZP3 A;  2OUT A;  2EZW A;  3G36 A;  2I15 A;  3RSY A;  1R2A A;  3IM3 A; 
#chains in the Genus database with same CATH homology
 1R2A A;  2KYG A;  4RT4 A;  4RIQ A;  5HVZ A;  4RTA A;  2DRN A;  4ZP3 A;  2EZW A;  3IM4 A;  2IZY A;  3G36 A;  4F9K A;  1L6E A;  2H9R A;  3IM3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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