2IBPA

Crystal structure of citrate synthase from pyrobaculum aerophilum
Total Genus 153
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
153
sequence length
407
structure length
407
Chain Sequence
EQTVQVKTTGKILQSPCGPIIHGLEDVLIKSTSISDIDGEKGILWYRGYRIEELARLSTYEEVSYLILYGRLPTKRELEDYINRMKKYRELHPATVEVIRNLAKAHPMFALEAAVAAEGAYDEDNQKLIEALSVGRYKAEEKELAYRIAEKLVAKMPTIVAYHYRFSRGLEVVRPRDDLGHAANFLYMMFGREPDPLASRGIDLYLILHADHEVPASTFAAHVVASTLSDLYSSVAAAIAALKGPLHGGANEMAVRNYLEIGTPAKAKEIVEAATKPGGPKLMGVGHRVYKAYDPRAKIFKEFSRDYVAKFGDPQNLFAIASAIEQEVLSHPYFQQRKLYPNVDFWSGIAFYYMGIPYEYFTPIFAMSRVVGWVAHVLEYWENNRIFRPRACYIGPHDLQYIPLEQR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of a thermophilic protein complex stabilized by topologically interlinked chains.
pubmed doi rcsb
molecule tags Transferase
source organism Pyrobaculum aerophilum
molecule keywords Citrate synthase
total genus 153
structure length 407
sequence length 407
chains with identical sequence B
ec nomenclature ec 2.3.3.1: Citrate (Si)-synthase.
pdb deposition date 2006-09-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00285 Citrate_synt Citrate synthase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.230.10 Mainly Alpha Orthogonal Bundle Cytochrome p450-Terp; domain 2 Cytochrome P450-Terp, domain 2 2ibpA02
1.10.580.10 Mainly Alpha Orthogonal Bundle Citrate Synthase; domain 1 Citrate Synthase, domain 1 2ibpA01
4YBOA 4JAEA 1NXEA 3TQGA 2C6XA 1A59A 1OWBA 2IFCA 1VGPA 4JAFA 4E6YA 3MSUA 2CTSA 4XGHA 1AL6A 2H12A 4CTSA 5CSCA 1VGMA 1CSSA 3HWKA 1CSCA 4G6BA 1CSRA 2IBPA 5CTSA 2CSCA 5CSCB 1CSHA 2R26A 1AMZA 3ENJA 2R9EA 1CSIA 1IXEA 6CTSA 1IOMA 1NXGA 4CSCA 4TVMA 1CTSA 3O8JA 4JADA 4JAGA 1OWCA 3CSCA 2P2WA 1O7XA 1AJ8A 6CSCA
chains in the Genus database with same CATH superfamily
4YBOA 4JAEA 1NXEA 3TQGA 2C6XA 1A59A 1OWBA 2IFCA 1VGPA 4JAFA 4E6YA 3MSUA 2CTSA 4XGHA 1AL6A 2H12A 4CTSA 5CSCA 1VGMA 1CSSA 3HWKA 1CSCA 4G6BA 1CSRA 2IBPA 5CTSA 2CSCA 5CSCB 1CSHA 2R26A 1AMZA 3ENJA 2R9EA 1CSIA 1IXEA 6CTSA 1IOMA 1NXGA 4CSCA 4TVMA 1CTSA 3O8JA 4JADA 4JAGA 1OWCA 3CSCA 2P2WA 1O7XA 1AJ8A 6CSCA
chains in the Genus database with same CATH topology
4YBOA 4JAEA 1NXEA 3TQGA 2C6XA 1A59A 1OWBA 2IFCA 1VGPA 4JAFA 4E6YA 3MSUA 2CTSA 4XGHA 1AL6A 2H12A 4CTSA 5CSCA 1VGMA 1CSSA 3HWKA 1CSCA 4G6BA 1CSRA 2IBPA 5CTSA 2CSCA 5CSCB 1CSHA 2R26A 1AMZA 3ENJA 2R9EA 1CSIA 1IXEA 6CTSA 1IOMA 1NXGA 4CSCA 4TVMA 1CTSA 3O8JA 4JADA 4JAGA 1OWCA 3CSCA 2P2WA 1O7XA 1AJ8A 6CSCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YBO A;  4JAE A;  1NXE A;  3TQG A;  2C6X A;  1A59 A;  1OWB A;  2IFC A;  1VGP A;  4JAF A;  4E6Y A;  3MSU A;  2CTS A;  4XGH A;  1AL6 A;  2H12 A;  4CTS A;  5CSC A;  1VGM A;  1CSS A;  3HWK A;  1CSC A;  4G6B A;  1CSR A;  2IBP A;  5CTS A;  2CSC A;  5CSC B;  1CSH A;  2R26 A;  1AMZ A;  3ENJ A;  2R9E A;  1CSI A;  1IXE A;  6CTS A;  1IOM A;  1NXG A;  4CSC A;  4TVM A;  1CTS A;  3O8J A;  4JAD A;  4JAG A;  1OWC A;  3CSC A;  2P2W A;  1O7X A;  1AJ8 A;  6CSC A; 
#chains in the Genus database with same CATH topology
 4YBO A;  4JAE A;  1NXE A;  3TQG A;  2C6X A;  1A59 A;  1OWB A;  2IFC A;  1VGP A;  4JAF A;  4E6Y A;  3MSU A;  2CTS A;  4XGH A;  1AL6 A;  2H12 A;  4CTS A;  5CSC A;  1VGM A;  1CSS A;  3HWK A;  1CSC A;  4G6B A;  1CSR A;  2IBP A;  5CTS A;  2CSC A;  5CSC B;  1CSH A;  2R26 A;  1AMZ A;  3ENJ A;  2R9E A;  1CSI A;  1IXE A;  6CTS A;  1IOM A;  1NXG A;  4CSC A;  4TVM A;  1CTS A;  3O8J A;  4JAD A;  4JAG A;  1OWC A;  3CSC A;  2P2W A;  1O7X A;  1AJ8 A;  6CSC A; 
#chains in the Genus database with same CATH homology
 4YBO A;  4JAE A;  1NXE A;  3TQG A;  2C6X A;  1A59 A;  1OWB A;  2IFC A;  1VGP A;  4JAF A;  4E6Y A;  3MSU A;  2CTS A;  4XGH A;  1AL6 A;  2H12 A;  4CTS A;  5CSC A;  1VGM A;  1CSS A;  3HWK A;  1CSC A;  4G6B A;  1CSR A;  2IBP A;  5CTS A;  2CSC A;  5CSC B;  1CSH A;  2R26 A;  1AMZ A;  3ENJ A;  2R9E A;  1CSI A;  1IXE A;  6CTS A;  1IOM A;  1NXG A;  4CSC A;  4TVM A;  1CTS A;  3O8J A;  4JAD A;  4JAG A;  1OWC A;  3CSC A;  2P2W A;  1O7X A;  1AJ8 A;  6CSC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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