2KYGA

Structure of the aml1-eto nervy domain - pka(riia) complex and its contribution to aml1-eto activity
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
50
structure length
50
Chain Sequence
GAMGSMSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the AML1-ETO NHR3-PKA(RIIalpha) complex and its contribution to AML1-ETO activity.
pubmed doi rcsb
molecule keywords cAMP-dependent protein kinase type II-alpha regulatory subun
molecule tags Protein binding
source organism Homo sapiens
total genus 13
structure length 50
sequence length 50
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-05-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02197 RIIa Regulatory subunit of type II PKA R-subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.890.10 Mainly Alpha Up-down Bundle cAMP-dependent Protein Kinase, Chain A cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 2kygA00
5HVZA 4RIQA 2H9RA 2DRNA 2EZWA 4RTAA 3IM4A 4ZP3A 4F9KA 2KYGA 4RT4A 3IM3A 1R2AA 2IZYA 3G36A 1L6EA
chains in the Genus database with same CATH superfamily
4RIQA 2K9QA 3QDEA 2H9RA 3RRSA 3PMIA 2OUTA 4ZP3A 2KNGA 1R2AA 3QG0A 3G36A 3S4BA 4RTAA 2DRNA 2CB9A 3S4CA 2I15A 2IZYA 5HVZA 3QFZA 3IM4A 3QFYA 3ACSA 2KYGA 3RSYA 2CQSA 2CQTA 3IM3A 3S4AA 1L6EA 2RQYA 3S4DA 3AFJA 2EZWA 3ACTA 3UFEA 3GWHA 2CBGA 4RT4A 4F9KA
chains in the Genus database with same CATH topology
5HVZA 4RIQA 2H9RA 2DRNA 2EZWA 4RTAA 3IM4A 4ZP3A 4F9KA 2KYGA 4RT4A 3IM3A 1R2AA 2IZYA 3G36A 1L6EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HVZ A;  4RIQ A;  2H9R A;  2DRN A;  2EZW A;  4RTA A;  3IM4 A;  4ZP3 A;  4F9K A;  2KYG A;  4RT4 A;  3IM3 A;  1R2A A;  2IZY A;  3G36 A;  1L6E A; 
#chains in the Genus database with same CATH topology
 4RIQ A;  2K9Q A;  3QDE A;  2H9R A;  3RRS A;  3PMI A;  2OUT A;  4ZP3 A;  2KNG A;  1R2A A;  3QG0 A;  3G36 A;  3S4B A;  4RTA A;  2DRN A;  2CB9 A;  3S4C A;  2I15 A;  2IZY A;  5HVZ A;  3QFZ A;  3IM4 A;  3QFY A;  3ACS A;  2KYG A;  3RSY A;  2CQS A;  2CQT A;  3IM3 A;  3S4A A;  1L6E A;  2RQY A;  3S4D A;  3AFJ A;  2EZW A;  3ACT A;  3UFE A;  3GWH A;  2CBG A;  4RT4 A;  4F9K A; 
#chains in the Genus database with same CATH homology
 5HVZ A;  4RIQ A;  2H9R A;  2DRN A;  2EZW A;  4RTA A;  3IM4 A;  4ZP3 A;  4F9K A;  2KYG A;  4RT4 A;  3IM3 A;  1R2A A;  2IZY A;  3G36 A;  1L6E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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