2KYGA

Structure of the aml1-eto nervy domain - pka(riia) complex and its contribution to aml1-eto activity
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
50
structure length
50
Chain Sequence
GAMGSMSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the AML1-ETO NHR3-PKA(RIIalpha) complex and its contribution to AML1-ETO activity.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords cAMP-dependent protein kinase type II-alpha regulatory subun
total genus 13
structure length 50
sequence length 50
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-05-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02197 RIIa Regulatory subunit of type II PKA R-subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.890.10 Mainly Alpha Up-down Bundle cAMP-dependent Protein Kinase, Chain A cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 2kygA00
2H9RA 3G36A 4F9KA 4RT4A 2EZWA 1L6EA 5HVZA 2DRNA 4RIQA 2KYGA 1R2AA 3IM4A 4ZP3A 3IM3A 4RTAA 2IZYA
chains in the Genus database with same CATH superfamily
3ACTA 2H9RA 4F9KA 2RQYA 3QFYA 4RT4A 2CQSA 4RIQA 4ZP3A 3IM3A 3ACSA 2K9QA 3S4CA 3G36A 2KNGA 3QG0A 3RSYA 2EZWA 3S4AA 3UFEA 2CQTA 3GWHA 1L6EA 5HVZA 3AFJA 3PMIA 1R2AA 3IM4A 4RTAA 2IZYA 3S4BA 3RRSA 3QFZA 3QDEA 2DRNA 3S4DA 2CB9A 2CBGA 2KYGA 2I15A 2OUTA
chains in the Genus database with same CATH topology
2H9RA 3G36A 4F9KA 4RT4A 2EZWA 1L6EA 5HVZA 2DRNA 4RIQA 2KYGA 1R2AA 3IM4A 4ZP3A 3IM3A 4RTAA 2IZYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2H9R A;  3G36 A;  4F9K A;  4RT4 A;  2EZW A;  1L6E A;  5HVZ A;  2DRN A;  4RIQ A;  2KYG A;  1R2A A;  3IM4 A;  4ZP3 A;  3IM3 A;  4RTA A;  2IZY A; 
#chains in the Genus database with same CATH topology
 3ACT A;  2H9R A;  4F9K A;  2RQY A;  3QFY A;  4RT4 A;  2CQS A;  4RIQ A;  4ZP3 A;  3IM3 A;  3ACS A;  2K9Q A;  3S4C A;  3G36 A;  2KNG A;  3QG0 A;  3RSY A;  2EZW A;  3S4A A;  3UFE A;  2CQT A;  3GWH A;  1L6E A;  5HVZ A;  3AFJ A;  3PMI A;  1R2A A;  3IM4 A;  4RTA A;  2IZY A;  3S4B A;  3RRS A;  3QFZ A;  3QDE A;  2DRN A;  3S4D A;  2CB9 A;  2CBG A;  2KYG A;  2I15 A;  2OUT A; 
#chains in the Genus database with same CATH homology
 2H9R A;  3G36 A;  4F9K A;  4RT4 A;  2EZW A;  1L6E A;  5HVZ A;  2DRN A;  4RIQ A;  2KYG A;  1R2A A;  3IM4 A;  4ZP3 A;  3IM3 A;  4RTA A;  2IZY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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