2POLA

Three-dimensional structure of the beta subunit of escherichia coli dna polymerase iii holoenzyme: a sliding dna clamp
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
366
structure length
366
Chain Sequence
MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Three-dimensional structure of the beta subunit of E. coli DNA polymerase III holoenzyme: a sliding DNA clamp.
pubmed doi rcsb
molecule tags Nucleotidyltransferase
source organism Escherichia coli
molecule keywords DNA POLYMERASE III (BETA SUBUNIT)
total genus 84
structure length 366
sequence length 366
chains with identical sequence B
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 1992-11-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
A PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
A PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 2polA02
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 2polA03
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 2polA01
3T0PA 3L0WA 1MMIA 2AVTA 4TR7A 5FVEA 3D1FA 4K74A 5FRQA 4K3MA 5AH2A 4TSZA 4N98A 4K3LA 3Q4LA 3P16A 4MJPA 4TRTA 1JQJA 4OVFA 4RKIA 1OK7A 4OVHA 4K3PA 4MJRA 4N94A 4N95A 3PWEA 4N9AA 4PNUA 4TR6A 4MJQA 4N99A 4PNWA 5AGUA 4K3RA 3BEPA 4N97A 3QSBA 4PNVA 2XURA 3L10A 3Q4JA 3D1GA 1UNNA 4K3OA 2POLA 3QSBB 5AH4A 1JQLA 4OVGA 4K3SA 5AGVA 4K3KA 4K3QA 1VPKA 3Q4KA 3F1VA 3L0XA 4N96A 3D1EA 3PGEB 2AWAA 3RB9A 4TR8A 4S3IA
chains in the Genus database with same CATH superfamily
3T0PA 3L0WA 1MMIA 3RB9A 2AVTA 3PGEA 4TR7A 5FVEA 3D1FA 4K74A 5FRQA 4K3MA 5AH2A 4TSZA 4N98A 4K3LA 3Q4LA 3P16A 4MJPA 4TRTA 1JQJA 4OVFA 4RKIA 1OK7A 4OVHA 4K3PA 4MJRA 4N94A 4N95A 3L10B 3PWEA 4N9AA 4PNUA 4TR6A 4MJQA 4N99A 4PNWA 5AGUA 4K3RA 3BEPA 4N97A 3QSBA 4PNVA 2XURA 3L10A 3Q4JA 3D1GA 3L0XB 1UNNA 4K3OA 2POLA 3QSBB 5AH4A 1JQLA 4OVGA 4K3SA 5AGVA 4K3KA 4K3QA 1VPKA 3L0WB 3F1VA 3L0XA 3Q4KA 3D1EA 3PGEB 2AWAA 4N96A 4TR8A 4S3IA
chains in the Genus database with same CATH topology
3T0PA 3L0WA 1MMIA 2AVTA 4TR7A 5FVEA 3D1FA 4K74A 5FRQA 4K3MA 5AH2A 4TSZA 4N98A 4K3LA 3Q4LA 3P16A 4MJPA 4TRTA 1JQJA 4OVFA 4RKIA 1OK7A 4OVHA 4K3PA 4MJRA 4N94A 4N95A 3PWEA 4N9AA 4PNUA 4TR6A 4MJQA 4N99A 4PNWA 5AGUA 4K3RA 3BEPA 4N97A 3QSBA 4PNVA 2XURA 3L10A 3Q4JA 3D1GA 1UNNA 4K3OA 2POLA 3QSBB 5AH4A 1JQLA 4OVGA 4K3SA 5AGVA 4K3KA 4K3QA 1VPKA 3Q4KA 3F1VA 3L0XA 4N96A 3D1EA 3PGEB 2AWAA 3RB9A 4TR8A 4S3IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T0P A;  3L0W A;  1MMI A;  2AVT A;  4TR7 A;  5FVE A;  3D1F A;  4K74 A;  5FRQ A;  4K3M A;  5AH2 A;  4TSZ A;  4N98 A;  4K3L A;  3Q4L A;  3P16 A;  4MJP A;  4TRT A;  1JQJ A;  4OVF A;  4RKI A;  1OK7 A;  4OVH A;  4K3P A;  4MJR A;  4N94 A;  4N95 A;  3PWE A;  4N9A A;  4PNU A;  4TR6 A;  4MJQ A;  4N99 A;  4PNW A;  5AGU A;  4K3R A;  3BEP A;  4N97 A;  3QSB A;  4PNV A;  2XUR A;  3L10 A;  3Q4J A;  3D1G A;  1UNN A;  4K3O A;  2POL A;  3QSB B;  5AH4 A;  1JQL A;  4OVG A;  4K3S A;  5AGV A;  4K3K A;  4K3Q A;  1VPK A;  3Q4K A;  3F1V A;  3L0X A;  4N96 A;  3D1E A;  3PGE B;  2AWA A;  3RB9 A;  4TR8 A;  4S3I A; 
#chains in the Genus database with same CATH topology
 3T0P A;  3L0W A;  1MMI A;  3RB9 A;  2AVT A;  3PGE A;  4TR7 A;  5FVE A;  3D1F A;  4K74 A;  5FRQ A;  4K3M A;  5AH2 A;  4TSZ A;  4N98 A;  4K3L A;  3Q4L A;  3P16 A;  4MJP A;  4TRT A;  1JQJ A;  4OVF A;  4RKI A;  1OK7 A;  4OVH A;  4K3P A;  4MJR A;  4N94 A;  4N95 A;  3L10 B;  3PWE A;  4N9A A;  4PNU A;  4TR6 A;  4MJQ A;  4N99 A;  4PNW A;  5AGU A;  4K3R A;  3BEP A;  4N97 A;  3QSB A;  4PNV A;  2XUR A;  3L10 A;  3Q4J A;  3D1G A;  3L0X B;  1UNN A;  4K3O A;  2POL A;  3QSB B;  5AH4 A;  1JQL A;  4OVG A;  4K3S A;  5AGV A;  4K3K A;  4K3Q A;  1VPK A;  3L0W B;  3F1V A;  3L0X A;  3Q4K A;  3D1E A;  3PGE B;  2AWA A;  4N96 A;  4TR8 A;  4S3I A; 
#chains in the Genus database with same CATH homology
 3T0P A;  3L0W A;  1MMI A;  2AVT A;  4TR7 A;  5FVE A;  3D1F A;  4K74 A;  5FRQ A;  4K3M A;  5AH2 A;  4TSZ A;  4N98 A;  4K3L A;  3Q4L A;  3P16 A;  4MJP A;  4TRT A;  1JQJ A;  4OVF A;  4RKI A;  1OK7 A;  4OVH A;  4K3P A;  4MJR A;  4N94 A;  4N95 A;  3PWE A;  4N9A A;  4PNU A;  4TR6 A;  4MJQ A;  4N99 A;  4PNW A;  5AGU A;  4K3R A;  3BEP A;  4N97 A;  3QSB A;  4PNV A;  2XUR A;  3L10 A;  3Q4J A;  3D1G A;  1UNN A;  4K3O A;  2POL A;  3QSB B;  5AH4 A;  1JQL A;  4OVG A;  4K3S A;  5AGV A;  4K3K A;  4K3Q A;  1VPK A;  3Q4K A;  3F1V A;  3L0X A;  4N96 A;  3D1E A;  3PGE B;  2AWA A;  3RB9 A;  4TR8 A;  4S3I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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