2Y9XA

Crystal structure of ppo3, a tyrosinase from agaricus bisporus, in deoxy-form that contains additional unknown lectin-like subunit, with inhibitor tropolone
Total Genus 124
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
124
sequence length
391
structure length
391
Chain Sequence
SDKKSLMPLVGIPGEIKNRLNILDFVKNDKFFTLYVRALQVLQARDQSDYSSFFQLGGIHGLPYTEWAKAQPQLHLYKANYCTHGTVLFPTWHRAYESTWEQTLWEAAGTVAQRFTTSDQAEWIQAAKDLRQPFWDWGYWPNDPDFIGLPDQVIRDKQVEITDYNGTKIEVENPILHYKFHPIEPTFEGDFAQWQTTMRYPDVQKQENIEGMIAGIKAAAPGFREWTFNMLTKNYTWELFSNHGAVVGAHANSLEMVHNTVHFLIGRDPTLDPLVPGHMGSVPHAAFDPIFWMHHCNVDRLLALWQTMNYDVYVSEGMNREATMGLIPGQVLTEDSPLEPFYTKNQDPWQSDDLEDWETLGFSYPDFDPVKGKSKEEKSVYINDWVHKHYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal Structure of Agaricus Bisporus Mushroom Tyrosinase: Identity of the Tetramer Subunits and Interaction with Tropolone.
pubmed doi rcsb
molecule keywords POLYPHENOL OXIDASE
molecule tags Oxidoreductase
total genus 124
structure length 391
sequence length 391
chains with identical sequence B, C, D
ec nomenclature ec 1.14.18.1: Tyrosinase.
pdb deposition date 2011-02-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00264 Tyrosinase Common central domain of tyrosinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1280.10 Mainly Alpha Orthogonal Bundle di-copper center containing domain from catechol oxidase Di-copper center containing domain from catechol oxidase 2y9xA00
4HD4A 2AHKA 5I38A 3NQ1A 3AWWA 3NM8A 3AWUA 3AX0A 4P6TA 3HHSA 2ZMXA 4YZWA 3NQ5A 2ZMYA 2ZWEA 1LNLA 3WJMB 2ZWFA 2ZWDA 4J3QA 4Z0YA 4J3RA 3HHSB 3AWYA 3WKYA 3AWZA 3WJMA 5CE9A 4L37B 4J6VA 3W6QA 3W6WA 2Y9XA 4HD6A 2ZWGA 1JS8A 4L37A 3AWTA 3AWXA 5I3BA 4Z0ZA 3QJOA 1OXYA 4J6UA 5I3AA 2AHLA 1WX2A 1LLAA 1NOLA 4P6RA 2Y9WA 2ZMZA 3NTMA 1LL1A 1BT2A 4OUAB 1WXCA 3AWVA 4J3PA 4HD7A 4J6TA 1BT1A 3AWSA 1HCYA 1WX4A 4Z10A 2P3XA 4OUAA 4D87A 1HC1A 3NQ0A 4P6SA 1WX5A 1BUGA 1BT3A 3GWJA 3NPYA
chains in the Genus database with same CATH superfamily
4HD4A 2AHKA 5I38A 3NQ1A 3AWWA 3NM8A 3AWUA 3AX0A 4P6TA 3HHSA 2ZMXA 4YZWA 3NQ5A 2ZMYA 2ZWEA 1LNLA 3WJMB 2ZWFA 2ZWDA 4J3QA 4Z0YA 4J3RA 3HHSB 3AWYA 3WKYA 3AWZA 3WJMA 5CE9A 4L37B 4J6VA 3W6QA 3W6WA 2Y9XA 4HD6A 2ZWGA 1JS8A 4L37A 3AWTA 3AWXA 5I3BA 4Z0ZA 3QJOA 1OXYA 4J6UA 5I3AA 2AHLA 1WX2A 1LLAA 1NOLA 4P6RA 2Y9WA 2ZMZA 3NTMA 1LL1A 1BT2A 4OUAB 1WXCA 3AWVA 4J3PA 4HD7A 4J6TA 1BT1A 3AWSA 1HCYA 1WX4A 4Z10A 2P3XA 4OUAA 4D87A 1HC1A 3NQ0A 4P6SA 1WX5A 1BUGA 1BT3A 3GWJA 3NPYA
chains in the Genus database with same CATH topology
4HD4A 2AHKA 5I38A 3NQ1A 3AWWA 3NM8A 3AWUA 3AX0A 4P6TA 3HHSA 2ZMXA 4YZWA 3NQ5A 2ZMYA 2ZWEA 1LNLA 3WJMB 2ZWFA 2ZWDA 4J3QA 4Z0YA 4J3RA 3HHSB 3AWYA 3WKYA 3AWZA 3WJMA 5CE9A 4L37B 4J6VA 3W6QA 3W6WA 2Y9XA 4HD6A 2ZWGA 1JS8A 4L37A 3AWTA 3AWXA 5I3BA 4Z0ZA 3QJOA 1OXYA 4J6UA 5I3AA 2AHLA 1WX2A 1LLAA 1NOLA 4P6RA 2Y9WA 2ZMZA 3NTMA 1LL1A 1BT2A 4OUAB 1WXCA 3AWVA 4J3PA 4HD7A 4J6TA 1BT1A 3AWSA 1HCYA 1WX4A 4Z10A 2P3XA 4OUAA 4D87A 1HC1A 3NQ0A 4P6SA 1WX5A 1BUGA 1BT3A 3GWJA 3NPYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HD4 A;  2AHK A;  5I38 A;  3NQ1 A;  3AWW A;  3NM8 A;  3AWU A;  3AX0 A;  4P6T A;  3HHS A;  2ZMX A;  4YZW A;  3NQ5 A;  2ZMY A;  2ZWE A;  1LNL A;  3WJM B;  2ZWF A;  2ZWD A;  4J3Q A;  4Z0Y A;  4J3R A;  3HHS B;  3AWY A;  3WKY A;  3AWZ A;  3WJM A;  5CE9 A;  4L37 B;  4J6V A;  3W6Q A;  3W6W A;  2Y9X A;  4HD6 A;  2ZWG A;  1JS8 A;  4L37 A;  3AWT A;  3AWX A;  5I3B A;  4Z0Z A;  3QJO A;  1OXY A;  4J6U A;  5I3A A;  2AHL A;  1WX2 A;  1LLA A;  1NOL A;  4P6R A;  2Y9W A;  2ZMZ A;  3NTM A;  1LL1 A;  1BT2 A;  4OUA B;  1WXC A;  3AWV A;  4J3P A;  4HD7 A;  4J6T A;  1BT1 A;  3AWS A;  1HCY A;  1WX4 A;  4Z10 A;  2P3X A;  4OUA A;  4D87 A;  1HC1 A;  3NQ0 A;  4P6S A;  1WX5 A;  1BUG A;  1BT3 A;  3GWJ A;  3NPY A; 
#chains in the Genus database with same CATH topology
 4HD4 A;  2AHK A;  5I38 A;  3NQ1 A;  3AWW A;  3NM8 A;  3AWU A;  3AX0 A;  4P6T A;  3HHS A;  2ZMX A;  4YZW A;  3NQ5 A;  2ZMY A;  2ZWE A;  1LNL A;  3WJM B;  2ZWF A;  2ZWD A;  4J3Q A;  4Z0Y A;  4J3R A;  3HHS B;  3AWY A;  3WKY A;  3AWZ A;  3WJM A;  5CE9 A;  4L37 B;  4J6V A;  3W6Q A;  3W6W A;  2Y9X A;  4HD6 A;  2ZWG A;  1JS8 A;  4L37 A;  3AWT A;  3AWX A;  5I3B A;  4Z0Z A;  3QJO A;  1OXY A;  4J6U A;  5I3A A;  2AHL A;  1WX2 A;  1LLA A;  1NOL A;  4P6R A;  2Y9W A;  2ZMZ A;  3NTM A;  1LL1 A;  1BT2 A;  4OUA B;  1WXC A;  3AWV A;  4J3P A;  4HD7 A;  4J6T A;  1BT1 A;  3AWS A;  1HCY A;  1WX4 A;  4Z10 A;  2P3X A;  4OUA A;  4D87 A;  1HC1 A;  3NQ0 A;  4P6S A;  1WX5 A;  1BUG A;  1BT3 A;  3GWJ A;  3NPY A; 
#chains in the Genus database with same CATH homology
 4HD4 A;  2AHK A;  5I38 A;  3NQ1 A;  3AWW A;  3NM8 A;  3AWU A;  3AX0 A;  4P6T A;  3HHS A;  2ZMX A;  4YZW A;  3NQ5 A;  2ZMY A;  2ZWE A;  1LNL A;  3WJM B;  2ZWF A;  2ZWD A;  4J3Q A;  4Z0Y A;  4J3R A;  3HHS B;  3AWY A;  3WKY A;  3AWZ A;  3WJM A;  5CE9 A;  4L37 B;  4J6V A;  3W6Q A;  3W6W A;  2Y9X A;  4HD6 A;  2ZWG A;  1JS8 A;  4L37 A;  3AWT A;  3AWX A;  5I3B A;  4Z0Z A;  3QJO A;  1OXY A;  4J6U A;  5I3A A;  2AHL A;  1WX2 A;  1LLA A;  1NOL A;  4P6R A;  2Y9W A;  2ZMZ A;  3NTM A;  1LL1 A;  1BT2 A;  4OUA B;  1WXC A;  3AWV A;  4J3P A;  4HD7 A;  4J6T A;  1BT1 A;  3AWS A;  1HCY A;  1WX4 A;  4Z10 A;  2P3X A;  4OUA A;  4D87 A;  1HC1 A;  3NQ0 A;  4P6S A;  1WX5 A;  1BUG A;  1BT3 A;  3GWJ A;  3NPY A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...