2YZBA

Crystal structure of uricase from arthrobacter globiformis in complex with uric acid (substrate)
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
287
structure length
287
Chain Sequence
TKVVLGQNQYGKAEVRLVKVTRNTARHEIQDLNVTSQLRGDFEAAHTAGDNAHVVATDTQKNTVYAFARDGFATTEEFLLRLGKHFTEGFDWVTGGRWAAQQFFWDRINDHDHAFSRNKSEVRTAVLEISGSEQAIVAGIEGLTVLKSTGSEFHGFPRDKYTTLQETTDRILATDVSARWRYNTVEVDFDAVYASVRGLLLKAFAETHSLALQQTMYEMGRAVIETHPEIDEIKMSLPNKHHFLVDLQPFGQDNPNEVFYAADRPYGLIEATIQREGSRADHPIWSN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Uricase
publication title Trapping of the uric acid substrate in the crystal structure of urate oxidase from Arthrobacter globiformis
rcsb
total genus 75
structure length 287
sequence length 287
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 1.7.3.3: Factor independent urate hydroxylase.
pdb deposition date 2007-05-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01014 Uricase Uricase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.270.10 Alpha Beta Roll Urate Oxidase Urate Oxidase; 2yzbA00
3PKLA 4R8XA 3PKHA 4CW0A 2YZBA 3PLJA 4N3MA 1WS2A 3OBPA 2ZKBA 1XXJA 3LBGA 4MB8A 1R4SA 2R5RA 4OP6A 1WRRA 3BK8A 4N9MA 1R4UA 3LD4A 2IBAA 2YZCA 3PK4A 3WLVA 3F2MA 3P9OA 4D19A 4R99A 3PLMA 1J2GA 5AYJA 4CW3A 3PLIA 4POEA 4D13A 3P9FA 1XT4A 1VAYA 2YZDA 3PK8A 2ZKAA 4N9VA 4OQCA 3BJPA 3L9GA 4D12A 4OP9A 1WS3A 5K9GA 3PKUA 2IC0A 1XY3A 2FXLA 5LL1A 3PK6A 3CKSA 3PLEA 3PKGA 5K95A 3PJKA 2ICQA 4D17A 4CW2A 1R51A 3PK5A 5M98A 4PUVA 3PKTA 4FSKA 4CW6A 3CKUA 1VAXA 3L8WA 3PKFA 3PLGA 1R56A 2YZEA 2FUBA 3PKKA 4N9SA 3D2OA 2PESA 5FRCA 3PK3A 3PKSA 3GKOA 4XFPA 4PR8A 3PLHA
chains in the Genus database with same CATH superfamily
3PKLA 4R8XA 3PKHA 4CW0A 2YZBA 3PLJA 4N3MA 1WS2A 3OBPA 2ZKBA 1XXJA 3LBGA 4MB8A 1R4SA 2R5RA 4OP6A 1WRRA 3BK8A 4N9MA 1R4UA 3LD4A 2IBAA 2YZCA 3PK4A 3WLVA 3F2MA 3P9OA 4D19A 4R99A 3PLMA 1J2GA 5AYJA 4CW3A 3PLIA 4POEA 4D13A 3P9FA 1XT4A 1VAYA 2YZDA 3PK8A 2ZKAA 4N9VA 4OQCA 3BJPA 3L9GA 4D12A 4OP9A 1WS3A 5K9GA 3PKUA 2IC0A 1XY3A 2FXLA 5LL1A 3PK6A 3CKSA 3PLEA 3PKGA 5K95A 3PJKA 2ICQA 4D17A 4CW2A 1R51A 3PK5A 5M98A 4PUVA 3PKTA 4FSKA 4CW6A 3CKUA 1VAXA 3L8WA 3PKFA 3PLGA 1R56A 2YZEA 2FUBA 3PKKA 4N9SA 3D2OA 2PESA 5FRCA 3PK3A 3PKSA 3GKOA 4XFPA 4PR8A 3PLHA
chains in the Genus database with same CATH topology
3PKLA 4R8XA 3PKHA 4CW0A 2YZBA 3PLJA 4N3MA 1WS2A 3OBPA 2ZKBA 1XXJA 3LBGA 4MB8A 1R4SA 2R5RA 4OP6A 1WRRA 3BK8A 4N9MA 1R4UA 3LD4A 2IBAA 2YZCA 3PK4A 3WLVA 3F2MA 3P9OA 4D19A 4R99A 3PLMA 1J2GA 5AYJA 4CW3A 3PLIA 4POEA 4D13A 3P9FA 1XT4A 1VAYA 2YZDA 3PK8A 2ZKAA 4N9VA 4OQCA 3BJPA 3L9GA 4D12A 4OP9A 1WS3A 5K9GA 3PKUA 2IC0A 1XY3A 2FXLA 5LL1A 3PK6A 3CKSA 3PLEA 3PKGA 5K95A 3PJKA 2ICQA 4D17A 4CW2A 1R51A 3PK5A 5M98A 4PUVA 3PKTA 4FSKA 4CW6A 3CKUA 1VAXA 3L8WA 3PKFA 3PLGA 1R56A 2YZEA 2FUBA 3PKKA 4N9SA 3D2OA 2PESA 5FRCA 3PK3A 3PKSA 3GKOA 4XFPA 4PR8A 3PLHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PKL A;  4R8X A;  3PKH A;  4CW0 A;  2YZB A;  3PLJ A;  4N3M A;  1WS2 A;  3OBP A;  2ZKB A;  1XXJ A;  3LBG A;  4MB8 A;  1R4S A;  2R5R A;  4OP6 A;  1WRR A;  3BK8 A;  4N9M A;  1R4U A;  3LD4 A;  2IBA A;  2YZC A;  3PK4 A;  3WLV A;  3F2M A;  3P9O A;  4D19 A;  4R99 A;  3PLM A;  1J2G A;  5AYJ A;  4CW3 A;  3PLI A;  4POE A;  4D13 A;  3P9F A;  1XT4 A;  1VAY A;  2YZD A;  3PK8 A;  2ZKA A;  4N9V A;  4OQC A;  3BJP A;  3L9G A;  4D12 A;  4OP9 A;  1WS3 A;  5K9G A;  3PKU A;  2IC0 A;  1XY3 A;  2FXL A;  5LL1 A;  3PK6 A;  3CKS A;  3PLE A;  3PKG A;  5K95 A;  3PJK A;  2ICQ A;  4D17 A;  4CW2 A;  1R51 A;  3PK5 A;  5M98 A;  4PUV A;  3PKT A;  4FSK A;  4CW6 A;  3CKU A;  1VAX A;  3L8W A;  3PKF A;  3PLG A;  1R56 A;  2YZE A;  2FUB A;  3PKK A;  4N9S A;  3D2O A;  2PES A;  5FRC A;  3PK3 A;  3PKS A;  3GKO A;  4XFP A;  4PR8 A;  3PLH A; 
#chains in the Genus database with same CATH topology
 3PKL A;  4R8X A;  3PKH A;  4CW0 A;  2YZB A;  3PLJ A;  4N3M A;  1WS2 A;  3OBP A;  2ZKB A;  1XXJ A;  3LBG A;  4MB8 A;  1R4S A;  2R5R A;  4OP6 A;  1WRR A;  3BK8 A;  4N9M A;  1R4U A;  3LD4 A;  2IBA A;  2YZC A;  3PK4 A;  3WLV A;  3F2M A;  3P9O A;  4D19 A;  4R99 A;  3PLM A;  1J2G A;  5AYJ A;  4CW3 A;  3PLI A;  4POE A;  4D13 A;  3P9F A;  1XT4 A;  1VAY A;  2YZD A;  3PK8 A;  2ZKA A;  4N9V A;  4OQC A;  3BJP A;  3L9G A;  4D12 A;  4OP9 A;  1WS3 A;  5K9G A;  3PKU A;  2IC0 A;  1XY3 A;  2FXL A;  5LL1 A;  3PK6 A;  3CKS A;  3PLE A;  3PKG A;  5K95 A;  3PJK A;  2ICQ A;  4D17 A;  4CW2 A;  1R51 A;  3PK5 A;  5M98 A;  4PUV A;  3PKT A;  4FSK A;  4CW6 A;  3CKU A;  1VAX A;  3L8W A;  3PKF A;  3PLG A;  1R56 A;  2YZE A;  2FUB A;  3PKK A;  4N9S A;  3D2O A;  2PES A;  5FRC A;  3PK3 A;  3PKS A;  3GKO A;  4XFP A;  4PR8 A;  3PLH A; 
#chains in the Genus database with same CATH homology
 3PKL A;  4R8X A;  3PKH A;  4CW0 A;  2YZB A;  3PLJ A;  4N3M A;  1WS2 A;  3OBP A;  2ZKB A;  1XXJ A;  3LBG A;  4MB8 A;  1R4S A;  2R5R A;  4OP6 A;  1WRR A;  3BK8 A;  4N9M A;  1R4U A;  3LD4 A;  2IBA A;  2YZC A;  3PK4 A;  3WLV A;  3F2M A;  3P9O A;  4D19 A;  4R99 A;  3PLM A;  1J2G A;  5AYJ A;  4CW3 A;  3PLI A;  4POE A;  4D13 A;  3P9F A;  1XT4 A;  1VAY A;  2YZD A;  3PK8 A;  2ZKA A;  4N9V A;  4OQC A;  3BJP A;  3L9G A;  4D12 A;  4OP9 A;  1WS3 A;  5K9G A;  3PKU A;  2IC0 A;  1XY3 A;  2FXL A;  5LL1 A;  3PK6 A;  3CKS A;  3PLE A;  3PKG A;  5K95 A;  3PJK A;  2ICQ A;  4D17 A;  4CW2 A;  1R51 A;  3PK5 A;  5M98 A;  4PUV A;  3PKT A;  4FSK A;  4CW6 A;  3CKU A;  1VAX A;  3L8W A;  3PKF A;  3PLG A;  1R56 A;  2YZE A;  2FUB A;  3PKK A;  4N9S A;  3D2O A;  2PES A;  5FRC A;  3PK3 A;  3PKS A;  3GKO A;  4XFP A;  4PR8 A;  3PLH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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